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D-Index & Metrics

Microbiology

D-Index
56
Citations
15913
World Ranking
3660
National Ranking
1437

Overview

Roman Dziarski is a researcher affiliated with Indiana University in the United States. Their work primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broader disciplines, their subfield focus includes Molecular Biology, Immunology, Genetics, Microbiology, and Epidemiology.

The scientist's research addresses topics such as Bacterial Genetics and Biotechnology, Protein Structure and Dynamics, Immune Response and Inflammation, Bacterial Infections and Vaccines, Gut Microbiota and Health, Immune Cells in Cancer, and Adipokines, Inflammation, and Metabolic Diseases.

Roman Dziarski has published in several journals, most notably in Scientific Reports (3 publications) and Trends in Molecular Medicine (1 publication). Their recent papers include:

  • Bacterial Peptidoglycan as a Driver of Chronic Brain Inflammation, 2020, Trends in Molecular Medicine
  • Nod2 protects mice from inflammation and obesity-dependent liver cancer, 2020, Scientific Reports
  • Formate dehydrogenase, ubiquinone, and cytochrome bd-I are required for peptidoglycan recognition protein-induced oxidative stress and killing in Escherichia coli, 2020, Scientific Reports
  • Respiratory chain components are required for peptidoglycan recognition protein-induced thiol depletion and killing in Bacillus subtilis and Escherichia coli, 2021, Scientific Reports

Their collaboration network features frequent co-authors including Dipika Gupta, Des R. Kashyap, Dominik A. Kowalczyk, Chun-Kai Yang, and Jon D. Laman.

In addition to journal articles, Roman Dziarski has contributed to book publications such as How We Outwitted and Survived the Nazis, published in 2023 by Academic Studies Press eBooks.

Best Publications

  • Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2

    Ralf Schwandner;Roman Dziarski;Holger Wesche;Mike Rothe

  • Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2

    Atsutoshi Yoshimura;Egil Lien;Robin R. Ingalls;Elaine Tuomanen

  • Peptidoglycan recognition proteins (PGRPs)

    Roman Dziarski

  • Peptidoglycan recognition proteins: a novel family of four human innate immunity pattern recognition molecules.

    Chao Liu;Zhaojun Xu;Dipika Gupta;Roman Dziarski

  • The peptidoglycan recognition proteins (PGRPs)

    Roman Dziarski;Dipika Gupta

  • Peptidoglycan recognition proteins: pleiotropic sensors and effectors of antimicrobial defences

    Julien Royet;Roman Dziarski

  • A Subset of Toll-Like Receptor Ligands Induces Cross-presentation by Bone Marrow-Derived Dendritic Cells

    Sandip K. Datta;Vanessa Redecke;Kiley R. Prilliman;Kenji Takabayashi

  • Peptidoglycan recognition proteins are a new class of human bactericidal proteins.

    Xiaofeng Lu;Minhui Wang;Jin Qi;Haitao Wang

  • Pglyrp-Regulated Gut Microflora Prevotella falsenii, Parabacteroides distasonis and Bacteroides eggerthii Enhance and Alistipes finegoldii Attenuates Colitis in Mice

    Roman Dziarski;Shin Yong Park;Des Raj Kashyap;Scot E. Dowd

  • Peptidoglycan recognition proteins: modulators of the microbiome and inflammation

    Julien Royet;Dipika Gupta;Roman Dziarski

  • Binding of bacterial peptidoglycan to CD14

    Roman Dziarski;Richard I. Tapping;Peter S. Tobias

  • Staphylococcus aureus peptidoglycan is a toll-like receptor 2 activator: a reevaluation.

    Roman Dziarski;Dipika Gupta

  • Mammalian peptidoglycan recognition protein binds peptidoglycan with high affinity, is expressed in neutrophils, and inhibits bacterial growth.

    Chao Liu;Eva Gelius;Gang Liu;Håkan Steiner

  • MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to gram-positive and gram-negative bacteria and their cell wall components

    Roman Dziarski;Qiuling Wang;Kensuke Miyake;Carsten J. Kirschning

  • Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine Amidase

    Zheng-Ming Wang;Xinna Li;Ross R. Cocklin;Minhui Wang

  • CD14 Is a Cell-activating Receptor for Bacterial Peptidoglycan

    Dipika Gupta;Theo N. Kirkland;Suganya Viriyakosol;Roman Dziarski

  • Chemokines are the main proinflammatory mediators in human monocytes activated by Staphylococcus aureus, peptidoglycan, and endotoxin.

    Zheng Ming Wang;Chao Liu;Roman Dziarski

  • Defect in neutrophil killing and increased susceptibility to infection with nonpathogenic gram-positive bacteria in peptidoglycan recognition protein-S (PGRP-S)-deficient mice

    Roman Dziarski;Kenneth A. Platt;Eva Gelius;Håkan Steiner

  • Recognition of bacterial peptidoglycan by the innate immune system.

    R. Dziarski

  • Review: Mammalian peptidoglycan recognition proteins (PGRPs) in innate immunity:

    Roman Dziarski;Dipika Gupta

  • Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures.

    B Weidemann;H Brade;E T Rietschel;R Dziarski

Frequent Co-Authors

Hans-Dieter Flad
Hans-Dieter Flad Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Ernst Th. Rietschel
Ernst Th. Rietschel Institute for Advanced Sustainability Studies
Artur J. Ulmer
Artur J. Ulmer University of Freiburg
Shoichi Kusumoto
Shoichi Kusumoto Osaka University
Mu Wang
Mu Wang Indiana University
Gabriel Núñez
Gabriel Núñez University of Michigan–Ann Arbor
Helmut Brade
Helmut Brade BOKU University
Elaine I. Tuomanen
Elaine I. Tuomanen St. Jude Children's Research Hospital
Jon D. Laman
Jon D. Laman University Medical Center Groningen
Douglas T. Golenbock
Douglas T. Golenbock University of Massachusetts Chan Medical School

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