Koichi Fukase

Overview

Best Publications

• Host Recognition of Bacterial Muramyl Dipeptide Mediated through NOD2 IMPLICATIONS FOR CROHN′S DISEASE

  Naohiro Inohara;Yasunori Ogura;Ana Fontalba;Olga Gutierrez

  2142
  Citations

• An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid.

  Mathias Chamaillard;Masahito Hashimoto;Yasuo Horie;Junya Masumoto

  1632
  Citations

• Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide

  Egil Lien;Terry K. Means;Holger Heine;Atsutoshi Yoshimura

  943
  Citations

• A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-κB activation

  Mizuho Hasegawa;Yukari Fujimoto;Peter C Lucas;Hiroyasu Nakano

  606
  Citations

• Monomeric and Polymeric Gram-Negative Peptidoglycan but Not Purified LPS Stimulate the Drosophila IMD Pathway

  Takashi Kaneko;Takashi Kaneko;William E. Goldman;Peter Mellroth;Hakan Steiner

  554
  Citations

• Crystal structures of human MD-2 and its complex with antiendotoxic lipid IVa.

  Umeharu Ohto;Koichi Fukase;Kensuke Miyake;Yoshinori Satow

  543
  Citations

• Lipopolysaccharide Interaction with Cell Surface Toll-like Receptor 4-MD-2 Higher Affinity than That with MD-2 or CD14

  Sachiko Akashi;Shin-ichiroh Saitoh;Yasutaka Wakabayashi;Takane Kikuchi

  514
  Citations

• Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response

  Sara W. Montminy;Naseema N. Khan;Sara C. McGrath;Mitchell J. Walkowicz

  482
  Citations

• Autophagic control of listeria through intracellular innate immune recognition in drosophila.

  Tamaki Yano;Shizuka Mita;Hiroko Ohmori;Yoshiteru Oshima

  445
  Citations

• Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines

  Akiko Uehara;Yukari Fujimoto;Koichi Fukase;Haruhiko Takada

  427
  Citations

• Structural basis of species-specific endotoxin sensing by innate immune receptor TLR4/MD-2

  Umeharu Ohto;Koichi Fukase;Kensuke Miyake;Toshiyuki Shimizu

  412
  Citations

• Human MD-2 confers on mouse Toll-like receptor 4 species-specific lipopolysaccharide recognition.

  Sachiko Akashi;Yoshinori Nagai;Hirotaka Ogata;Masato Oikawa

  310
  Citations

• Lipid A antagonist, lipid IVa, is distinct from lipid A in interaction with Toll-like receptor 4 (TLR4)-MD-2 and ligand-induced TLR4 oligomerization.

  Shin-ichiroh Saitoh;Sachiko Akashi;Takenao Yamada;Natsuko Tanimura

  305
  Citations

• Muramyldipeptide and diaminopimelic acid-containing desmuramylpeptides in combination with chemically synthesized Toll-like receptor agonists synergistically induced production of interleukin-8 in a NOD2- and NOD1-dependent manner, respectively, in human monocytic cells in culture.

  A. Uehara;S. Yang;Y. Fujimoto;K. Fukase

  304
  Citations

• Aggregates are the biologically active units of endotoxin.

  Mareike Mueller;Buko Lindner;Shoichi Kusumoto;Koichi Fukase

  297
  Citations

• Human Peptidoglycan Recognition Protein-L Is an N-Acetylmuramoyl-L-alanine Amidase

  Zheng-Ming Wang;Xinna Li;Ross R. Cocklin;Minhui Wang

  289
  Citations

• Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo.

  Junya Masumoto;Kangkang Yang;Sooryanarayana Varambally;Mizuho Hasegawa

  279
  Citations

• The NLRP6 Inflammasome Recognizes Lipoteichoic Acid and Regulates Gram-Positive Pathogen Infection

  Hideki Hara;Sergey S. Seregin;Dahai Yang;Koichi Fukase

  275
  Citations

• Intrinsic conformation of lipid A is responsible for agonistic and antagonistic activity.

  Ulrich Seydel;Masato Oikawa;Koichi Fukase;Shoichi Kusumoto

  266
  Citations

• Molecular basis for bacterial peptidoglycan recognition by LysM domains.

  Stéphane Mesnage;Mariano Dellarole;Nicola J. Baxter;Jean Baptiste Rouget

  238
  Citations

• Differential release and distribution of Nod1 and Nod2 immunostimulatory molecules among bacterial species and environments.

  Mizuho Hasegawa;Kangkang Yang;Masahito Hashimoto;Jong Hwan Park

  224
  Citations