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Gabriele Missale

Gabriele Missale

D-Index & Metrics

Microbiology

D-Index
69
Citations
18102
World Ranking
2030
National Ranking
50

Overview

Gabriele Missale is affiliated with the University of Parma in Italy and has contributed extensively to the field of medicine, with a particular focus on hepatology and immunology. Their research portfolio encompasses a broad range of topics within liver disease diagnosis and treatment, hepatocellular carcinoma, immune cell function, and viral hepatitis.

The scientist's main fields of study include medicine, epidemiology, hepatology, immunology, oncology, and infectious diseases. These fields reflect the interdisciplinary nature of their research, bridging clinical and immunological approaches to liver-related diseases.

Gabriele Missale has published numerous papers in notable venues. The frequent publication venues include:

  • Digestive and Liver Disease
  • Journal of Hepatology
  • Frontiers in Oncology
  • Gut
  • Frontiers in Immunology

Some of their recent papers are:

  • "Epidemiological trends and trajectories of MAFLD-associated hepatocellular carcinoma 2002-2033: the ITA.LI.CA database," 2021, Gut
  • "Pathogenetic Mechanisms of T Cell Dysfunction in Chronic HBV Infection and Related Therapeutic Approaches," 2020, Frontiers in Immunology
  • "The changing scenario of hepatocellular carcinoma in Italy: an update," 2020, Liver International
  • "Soluble PD-L1 and Circulating CD8+PD-1+ and NK Cells Enclose a Prognostic and Predictive Immune Effector Score in Immunotherapy Treated NSCLC patients," 2020, Lung Cancer
  • "Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection," 2020, Nature Communications

Gabriele Missale collaborates frequently with several coauthors, including:

  • Carlo Ferrari
  • Paola Fisicaro
  • Carolina Boni
  • Andrea Vecchi
  • Edoardo G. Giannini

The scientist's main research topics span:

  • Liver Disease Diagnosis and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Immune Cell Function and Interaction
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Cancer Immunotherapy and Biomarkers
  • SARS-CoV-2 and COVID-19 Research

Best Publications

  • Immunoglobulin G Fragment C Receptor Polymorphisms and Clinical Efficacy of Trastuzumab-Based Therapy in Patients With HER-2/neu–Positive Metastatic Breast Cancer

    Antonino Musolino;Nadia Naldi;Beatrice Bortesi;Debora Pezzuolo

  • Characterization of hepatitis B virus (HBV)-specific T-cell dysfunction in chronic HBV infection.

    Carolina Boni;Paola Fisicaro;Caterina Valdatta;Barbara Amadei

  • Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.

    Gabriele Missale;Roberto Bertoni;Vincenzo Lamonaca;Antonietta Valli

  • PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion

    Simona Urbani;Barbara Amadei;Daniela Tola;Marco Massari

  • Hepatitis B virus maintains its pro-oncogenic properties in the case of Occult HBV infection

    Teresa Pollicino;Giovanni Squadrito;Giovanni Cerenzia;Irene Cacciola

  • Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B.

    Paola Fisicaro;Caterina Valdatta;Marco Massari;Elisabetta Loggi

  • Different cytokine profiles of intraphepatic T cells in chronic hepatitis B and hepatitis C virus infections

    A Bertoletti;MM D'Elios;C Boni;M De Carli

  • Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen.

    A Penna;F V Chisari;A Bertoletti;G Missale

  • HLA A2 restricted cytotoxic T lymphocyte responses to multiple hepatitis B surface antigen epitopes during hepatitis B virus infection.

    R Nayersina;P Fowler;S Guilhot;G Missale

  • Restored function of HBV-specific T cells after long-term effective therapy with nucleos(t)ide analogues.

    Carolina Boni;Diletta Laccabue;Pietro Lampertico;Tiziana Giuberti

  • Dysfunction and functional restoration of HCV-specific CD8 responses in chronic hepatitis C virus infection.

    Amalia Penna;Massimo Pilli;Alessandro Zerbini;Alessandra Orlandini

  • Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen

    C Ferrari;A Bertoletti;A Penna;A Cavalli

  • Early kinetics of innate and adaptive immune responses during hepatitis B virus infection

    Paola Fisicaro;Caterina Valdatta;Carolina Boni;Marco Massari

  • Targeting mitochondrial dysfunction can restore antiviral activity of exhausted HBV-specific CD8 T cells in chronic hepatitis B

    Paola Fisicaro;Valeria Barili;Barbara Montanini;Greta Acerbi

  • Radiofrequency Thermal Ablation of Hepatocellular Carcinoma Liver Nodules Can Activate and Enhance Tumor-Specific T-Cell Responses

    Alessandro Zerbini;Massimo Pilli;Amalia Penna;Guido Pelosi

  • HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis.

    G Missale;A Redeker;P Fowler

  • Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B

    Carolina Boni;Amalia Penna;Antonio Bertoletti;Vincenzo Lamonaca

  • Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses.

    Simona Urbani;Barbara Amadei;Paola Fisicaro;Daniela Tola

  • Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo.

    Kazuki Ando;Luca G. Guidotti;Susanne Wirth;Tetsuya Ishikawa

  • IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection.

    Martin Lagging;Ana I. Romero;Johan Westin;Gunnar Norkrans

Frequent Co-Authors

Carlo Ferrari
Carlo Ferrari University of Parma
Fabio Farinati
Fabio Farinati University of Padua
Antonio Bertoletti
Antonio Bertoletti Duke NUS Graduate Medical School
Antonio Gasbarrini
Antonio Gasbarrini Catholic University of the Sacred Heart
Avidan U. Neumann
Avidan U. Neumann Bar-Ilan University
Fabio Piscaglia
Fabio Piscaglia University of Bologna
Marco Zoli
Marco Zoli University of Bologna
Francesco Negro
Francesco Negro University of Geneva

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