What is he best known for?
The fields of study he is best known for:
Roman Jerala focuses on Biochemistry, Protein structure, TLR4, Peptide and Protein secondary structure.
His work in Binding site, Enzyme, Antibacterial agent, Ectodomain and DNA gyrase is related to Biochemistry.
His Protein structure research integrates issues from Crystallography and Structural biology.
Roman Jerala interconnects Innate immune system, Toll-like receptor, Lipid A and Immunity in the investigation of issues within TLR4.
His Peptide research incorporates elements of Lactoferrin, Lipopeptide, Antimicrobial and Polymyxin B.
The various areas that Roman Jerala examines in his Protein secondary structure study include Protein tertiary structure, Circular dichroism and Protein folding.
His most cited work include:
- The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction. (417 citations)
- Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines (383 citations)
- Structural biology of the LPS recognition (226 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Biochemistry, Cell biology, Receptor, Stereochemistry and Peptide.
As a part of the same scientific study, Roman Jerala usually deals with the Biochemistry, concentrating on Lipid A and frequently concerns with Plasma protein binding.
Roman Jerala works mostly in the field of Cell biology, limiting it down to topics relating to HEK 293 cells and, in certain cases, Molecular biology, as a part of the same area of interest.
His Stereochemistry research includes elements of Residue and Molecule.
His Peptide research is multidisciplinary, incorporating elements of Lactoferrin and Lipopeptide.
The Innate immune system study combines topics in areas such as Microbiology and TLR4.
He most often published in these fields:
- Biochemistry (33.46%)
- Cell biology (18.11%)
- Receptor (13.39%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (18.11%)
- Coiled coil (5.91%)
- Computational biology (4.72%)
In recent papers he was focusing on the following fields of study:
His main research concerns Cell biology, Coiled coil, Computational biology, Modular design and Protein design.
His Cell biology study combines topics from a wide range of disciplines, such as HEK 293 cells, Receptor, Innate immune system and Cell fusion.
His Coiled coil research includes themes of Self-assembly, Dimer, Protein structure, Tetrahedron and Peptide.
His work in the fields of Synthetic biology overlaps with other areas such as CpG site.
In his work, Crystallography is strongly intertwined with Structural biology, which is a subfield of Protein design.
He works on Biochemistry which deals in particular with DNA.
Between 2017 and 2021, his most popular works were:
- Design of fast proteolysis-based signaling and logic circuits in mammalian cells. (55 citations)
- DNA-Free Genome Editing of Brassica oleracea and B. rapa Protoplasts Using CRISPR-Cas9 Ribonucleoprotein Complexes. (41 citations)
- NLRP3 lacking the leucine-rich repeat domain can be fully activated via the canonical inflammasome pathway. (31 citations)
In his most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cell biology, Peptide, Innate immune system, Coiled coil and Transcriptional regulation.
Roman Jerala works in the field of Cell biology, focusing on Signal transduction in particular.
His biological study spans a wide range of topics, including Conformational change, Nanotechnology and Synthetic biology.
His Innate immune system research is under the purview of Receptor.
His Coiled coil study also includes
- Protein design which is related to area like Metalloprotein, Biophysics, Molecular machine, Self-assembly and Dimer,
- Computational biology that intertwine with fields like DNA nanotechnology, Protein secondary structure, Structural biology and Protein structure.
His Flagellin research focuses on Toll-like receptor and how it connects with Binding site.
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