World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
65
Citations
14378
World Ranking
9193
National Ranking
7

Research.com Recognitions

  • 2017 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Roman Jerala is affiliated with the National Institute of Chemistry in Slovenia and has contributed extensively to the field of Biochemistry, Genetics, and Molecular Biology. Their research spans 154 publications, with a strong focus on Molecular Biology, Immunology, Infectious Diseases, Biomedical Engineering, and Oncology.

The scientist's main topics of work include:

  • CRISPR and Genetic Engineering
  • Advanced biosensing and bioanalysis techniques
  • RNA and protein synthesis mechanisms
  • Viral Infectious Diseases and Gene Expression in Insects
  • Monoclonal and Polyclonal Antibodies Research
  • CAR-T cell therapy research
  • Bacteriophages and microbial interactions

Roman Jerala's frequent coauthors reflect a collaborative research environment and include:

  • Duško Lainšček (27 joint publications)
  • Mojca Benčina (23 joint publications)
  • Jana Aupič (14 joint publications)
  • Iva Hafner-Bratkovič (13 joint publications)
  • Žiga Strmšek (13 joint publications)

The scientist has published frequently in the following venues:

  • Nature Communications (12 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (12 publications)
  • ACS Synthetic Biology (4 publications)
  • Methods in Molecular Biology (3 publications)
  • Nature Chemical Biology (2 publications)

Recent papers by Roman Jerala include:

  • "A tunable orthogonal coiled-coil interaction toolbox for engineering mammalian cells" (2020, Nature Chemical Biology)
  • "Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage" (2022, Nature Communications)
  • "Disruption of disulfides within RBD of SARS-CoV-2 spike protein prevents fusion and represents a target for viral entry inhibition by registered drugs" (2021, The FASEB Journal)
  • "Self-assembly and regulation of protein cages from pre-organised coiled-coil modules" (2021, Nature Communications)
  • "Correlation between Phenotype and Genotype in CTNNB1 Syndrome: A Systematic Review of the Literature" (2022, International Journal of Molecular Sciences)

Roman Jerala has been recognized with memberships in scientific organizations, including:

  • Member of Academia Europaea (2017)
  • Member of the European Molecular Biology Organization (EMBO)

Best Publications

  • The refined 2.4 A X-ray crystal structure of recombinant human stefin B in complex with the cysteine proteinase papain: a novel type of proteinase inhibitor interaction.

    M T Stubbs;B Laber;W Bode;R Huber

  • Mechanism of Endosomal TLR Inhibition by Antimalarial Drugs and Imidazoquinolines

    Alenka Kužnik;Mojca Benčina;Urban Švajger;Matjaž Jeras

  • Structural biology of the LPS recognition

    Roman Jerala

  • Characterization of quercetin binding site on DNA gyrase.

    Andreja Plaper;Mojca Golob;Iva Hafner;Marko Oblak

  • Design of a single-chain polypeptide tetrahedron assembled from coiled-coil segments

    Helena Gradišar;Sabina Božič;Tibor Doles;Damjan Vengust

  • Green Tea Catechins Inhibit Bacterial DNA Gyrase by Interaction with Its ATP Binding Site

    Helena Gradišar;Primož Pristovšek;and Andreja Plaper;Roman Jerala

  • DNA-guided assembly of biosynthetic pathways promotes improved catalytic efficiency

    Robert J. Conrado;Gabriel C. Wu;Jason T. Boock;Hansen Xu

  • Similarities and Specificities of Fungal Keratinolytic Proteases: Comparison of Keratinases of Paecilomyces marquandii and Doratomyces microsporus to Some Known Proteases

    Helena Gradisar;Jozica Friedrich;Igor Krizaj;Roman Jerala

  • Three-dimensional domain swapping in the folded and molten-globule states of cystatins, an amyloid-forming structural superfamily.

    Rosemary A. Staniforth;Silva Giannini;Lee D. Higgins;Matthew J. Conroy

  • Chemistry of Lipid A: At the Heart of Innate Immunity

    Antonio Molinaro;Otto Holst;Flaviana Di Lorenzo;Maire Callaghan

  • Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo.

    Ajasja Ljubetič;Fabio Lapenta;Helena Gradišar;Igor Drobnak

  • The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes.

    Magdalini Polymenidou;Rita Moos;Mike Scott;Christina Sigurdson

  • Primary structure of a new cysteine proteinase inhibitor from pig leucocytes

    Anka Ritonja;Majda Kopitar;Roman Jerala;Vito Turk

  • Toll-Like Receptor 4 Activation in Cancer Progression and Therapy

    Alja Oblak;Roman Jerala

  • Design of fast proteolysis-based signaling and logic circuits in mammalian cells

    Tina Fink;Jan Lonzarić;Arne Praznik;Tjaša Plaper

  • MD-2 as the target of curcumin in the inhibition of response to LPS

    Helena Gradišar;Mateja Manček Keber;Primož Pristovšek;Roman Jerala

  • Structural Model of MD-2 and Functional Role of Its Basic Amino Acid Clusters Involved in Cellular Lipopolysaccharide Recognition *

    Anton Gruber;Mateja Manček;Hermann Wagner;Carsten J. Kirschning

  • DNA-Free Genome Editing of Brassica oleracea and B. rapa Protoplasts Using CRISPR-Cas9 Ribonucleoprotein Complexes.

    Jana Murovec;Katja Guček;Borut Bohanec;Monika Avbelj

  • De novo design of orthogonal peptide pairs forming parallel coiled-coil heterodimers.

    Helena Gradišar;Roman Jerala

  • Curcumin binds to the α‐helical intermediate and to the amyloid form of prion protein – a new mechanism for the inhibition of PrPSc accumulation

    Iva Hafner-Bratkovič;Jernej Gašperšič;Lojze M. Šmid;Mara Bresjanac

Frequent Co-Authors

Vito Turk
Vito Turk Jožef Stefan Institute
Karl Lohner
Karl Lohner University of Graz
Jonathan P. Waltho
Jonathan P. Waltho University of Sheffield
Ignacio Moriyón
Ignacio Moriyón University of Navarra
Gregor Anderluh
Gregor Anderluh University of Ljubljana
Klaus Brandenburg
Klaus Brandenburg Leibniz Institute for Neurobiology
Jerrold Weiss
Jerrold Weiss University of Iowa
Rudi Beyaert
Rudi Beyaert Ghent University

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