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Biology and Biochemistry

D-Index
50
Citations
19097
World Ranking
17405
National Ranking
7152

Overview

Christina J. Sigurdson is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on biochemistry, genetics, molecular biology, medicine, and neuroscience. The subfields of study related to their work include molecular biology, neurology, physiology, cellular and molecular neuroscience, and biological psychiatry.

The main topics addressed in their publications encompass prion diseases and protein misfolding, neurological diseases and metabolism, Alzheimer's disease research and treatments, tryptophan and brain disorders, enzyme structure and function, trace elements in health, and cholinesterase and neurodegenerative diseases.

Frequent coauthors working alongside Christina J. Sigurdson are:

  • Katrin Soldau
  • Donald Pizzo
  • Patricia Aguilar-Calvo
  • Alejandro M. Sevillano
  • Timothy D. Kurt

Publications by Sigurdson appear in several recurring journals, including:

  • Journal of Biological Chemistry
  • Journal of Clinical Investigation
  • Journal of Neuropathology & Experimental Neurology
  • Neurobiology of Disease
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent papers include:

  • "Prion protein glycans reduce intracerebral fibril formation and spongiosis in prion disease," 2020, Journal of Clinical Investigation
  • "Scaling analysis reveals the mechanism and rates of prion replication in vivo," 2021, Nature Structural & Molecular Biology
  • "Distinct conformers of amyloid beta accumulate in the neocortex of patients with rapidly progressive Alzheimer's disease," 2021, Journal of Biological Chemistry
  • "Risk of Transmissibility From Neurodegenerative Disease-Associated Proteins: Experimental Knowns and Unknowns," 2020, Journal of Neuropathology & Experimental Neurology
  • "ARCAM-1 Facilitates Fluorescence Detection of Amyloid-Containing Deposits in the Retina," 2021, Translational Vision Science & Technology

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Infectious Prions in the Saliva and Blood of Deer with Chronic Wasting Disease

    Candace K. Mathiason;Jenny G. Powers;Sallie J. Dahmes;David A. Osborn

  • Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

    Mathias Heikenwalder;Magdalini Polymenidou;Tobias Junt;Christina Sigurdson

  • Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue.

    Marius Kollmer;William Close;Leonie Funk;Jay Rasmussen

  • Molecular mechanisms of prion pathogenesis

    Adriano Aguzzi;Christina Sigurdson;Mathias Heikenwaelder

  • Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus).

    Christina J. Sigurdson;Elizabeth S. Williams;Michael W. Miller;Terry R. Spraker

  • Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses

    Andreas Åslund;Christina J. Sigurdson;Therése Klingstedt;Stefan Grathwohl

  • Cell-to-cell transmission of non-prion protein aggregates.

    Seung-Jae Lee;Paula Desplats;Christina Sigurdson;Igor Tsigelny

  • Prion strain discrimination using luminescent conjugated polymers.

    Christina J Sigurdson;K Peter R Nilsson;Simone Hornemann;Giuseppe Manco

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Prions in skeletal muscles of deer with chronic wasting disease

    Rachel C. Angers;Shawn R. Browning;Tanya S. Seward;Christina J. Sigurdson

  • De novo generation of a transmissible spongiform encephalopathy by mouse transgenesis

    Christina J. Sigurdson;K. Peter R. Nilsson;Simone Hornemann;Mathias Heikenwalder

  • The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes.

    Magdalini Polymenidou;Rita Moos;Mike Scott;Christina Sigurdson

  • PrPSc in mammary glands of sheep affected by scrapie and mastitis.

    Ciriaco Ligios;Christina J Sigurdson;Cinzia Santucciu;Gabriella Carcassola

  • Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death

    Nobuhiko Hiramatsu;Wei-Chieh Chiang;Timothy D. Kurt;Christina J. Sigurdson

  • A prion disease of cervids: Chronic wasting disease

    Christina J Sigurdson

  • PrP CWD in the myenteric plexus, vagosympathetic trunk and endocrine glands of deer with chronic wasting disease

    Christina J. Sigurdson;Terry R. Spraker;Michael W. Miller;Bruno Oesch

  • A molecular switch controls interspecies prion disease transmission in mice

    Christina J. Sigurdson;K. Peter R. Nilsson;K. Peter R. Nilsson;Simone Hornemann;Simone Hornemann;Giuseppe Manco

  • Other animal prion diseases

    Christina J Sigurdson;Michael W Miller

Frequent Co-Authors

Adriano Aguzzi
Adriano Aguzzi University of Zurich
K. Peter R. Nilsson
K. Peter R. Nilsson Linköping University
Kurt Wüthrich
Kurt Wüthrich ETH Zurich
Eliezer Masliah
Eliezer Masliah National Institutes of Health
Terry R. Spraker
Terry R. Spraker Colorado State University
Markus Glatzel
Markus Glatzel Universität Hamburg
Edward A. Hoover
Edward A. Hoover Colorado State University
Petra Schwarz
Petra Schwarz University of Zurich
David Eisenberg
David Eisenberg Harvard University

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