What is she best known for?
The fields of study she is best known for:
- Biochemistry
- Genetics
- Amino acid
Christina J. Sigurdson mainly investigates Virology, Chronic wasting disease, Prion protein, Immunology and Neurodegeneration.
Christina J. Sigurdson combines subjects such as Scrapie, Transmissible spongiform encephalopathy, Pathogenesis, Bovine spongiform encephalopathy and Disease with her study of Virology.
Christina J. Sigurdson interconnects Transmission, Myenteric plexus and Sciatic nerve in the investigation of issues within Chronic wasting disease.
The Prion strain research she does as part of her general Prion protein study is frequently linked to other disciplines of science, such as Conjugated system, therefore creating a link between diverse domains of science.
In the subject of general Immunology, her work in Germinal center is often linked to TLR9, thereby combining diverse domains of study.
Her work deals with themes such as Ex vivo, In vivo and Biochemistry, which intersect with Amyloid.
Her most cited work include:
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
- Infectious Prions in the Saliva and Blood of Deer with Chronic Wasting Disease (403 citations)
- Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration (401 citations)
What are the main themes of her work throughout her whole career to date?
Christina J. Sigurdson mainly focuses on Virology, Amyloid, Chronic wasting disease, Cell biology and Neurodegeneration.
Her Virology study combines topics from a wide range of disciplines, such as Scrapie, Bovine spongiform encephalopathy, Disease and Prion protein.
The concepts of her Amyloid study are interwoven with issues in In vitro, Protein aggregation, Pathogenesis, Biophysics and PrPSc Proteins.
The various areas that she examines in her Chronic wasting disease study include Immunohistochemistry, Immunology and Transmissible spongiform encephalopathy.
Her Cell biology research includes elements of Fibril, Secretory protein and Protein structure.
Her Neurodegeneration research is multidisciplinary, incorporating elements of Heparan sulfate, Spleen, Endoplasmic reticulum and Central nervous system.
She most often published in these fields:
- Virology (47.41%)
- Amyloid (41.38%)
- Chronic wasting disease (25.86%)
What were the highlights of her more recent work (between 2018-2021)?
- Neurodegeneration (25.00%)
- Cell biology (27.59%)
- Fibril (17.24%)
In recent papers she was focusing on the following fields of study:
Her scientific interests lie mostly in Neurodegeneration, Cell biology, Fibril, Heparan sulfate and In vitro.
Her Neurodegeneration study incorporates themes from Virology, Bovine spongiform encephalopathy, Signal transduction, Chronic wasting disease and Amyloid.
Her Amyloid research incorporates themes from Gliosis, Glycosylation, Kuru and Protein folding.
Her work on Lipid raft and Cell signaling as part of general Cell biology research is often related to Neural cell adhesion molecule and LRP1, thus linking different fields of science.
Her studies deal with areas such as Molecular biology, Orders of magnitude and Tauopathy as well as Fibril.
Her In vitro study also includes fields such as
- In vivo together with Glycosaminoglycan and Prion protein,
- Biophysics and related Protein aggregation, Peptide and Neuropathology.
Between 2018 and 2021, her most popular works were:
- Cryo-EM structure and polymorphism of Aβ amyloid fibrils purified from Alzheimer's brain tissue. (110 citations)
- Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease. (41 citations)
- Cellular and Molecular Mechanisms of Prion Disease. (20 citations)
In her most recent research, the most cited papers focused on:
- Biochemistry
- Genetics
- Amino acid
Her primary scientific interests are in Neurodegeneration, Fibril, Heparan sulfate, Cell biology and In vitro.
She has researched Neurodegeneration in several fields, including Gliosis, Chronic wasting disease, Kuru and Amyloid.
Her Fibril research is multidisciplinary, relying on both Alzheimer's disease, Molecular biology and Tauopathy.
Her Heparan sulfate study combines topics in areas such as Extracellular, In vivo and Spongiosis.
In her study, Christina J. Sigurdson carries out multidisciplinary Cell biology and ADAM10 research.
Her research integrates issues of Biophysics, Aβ amyloid, Cerebral amyloid angiopathy, Neuropathology and Peptide in her study of In vitro.
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