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K. Peter R. Nilsson

K. Peter R. Nilsson

D-Index & Metrics

Chemistry

D-Index
50
Citations
8497
World Ranking
14423
National Ranking
215

Overview

K. Peter R. Nilsson is affiliated with Linköping University in Sweden and has a research focus that spans several areas within medicine and biochemistry. Their work encompasses physiology, neurology, molecular biology, pharmacology, and cellular and molecular neuroscience.

The main topics studied by Nilsson include:

  • Alzheimer's disease research and treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cholinesterase and Neurodegenerative Diseases
  • Prion Diseases and Protein Misfolding
  • Computational Drug Discovery Methods
  • Parkinson's Disease Mechanisms and Treatments
  • Neuroscience and Neuropharmacology Research

Among the recent papers authored or co-authored by Nilsson are:

  • "Discriminating α-synuclein strains in Parkinson's disease and multiple system atrophy," 2020, Nature
  • "Cellulose from the green macroalgae Ulva lactuca: isolation, characterization, optotracing, and production of cellulose nanofibrils," 2020, Cellulose
  • "Medin co-aggregates with vascular amyloid-β in Alzheimer's disease," 2022, Nature
  • "Multiscale optical and optoacoustic imaging of amyloid-β deposits in mice," 2022, Nature Biomedical Engineering
  • "Cellular localization of p-tau217 in brain and its association with p-tau217 plasma levels," 2022, Acta Neuropathologica Communications

The frequent co-authors working with Nilsson include:

  • Hamid Shirani (20 collaborations)
  • Therése Klingstedt (18 collaborations)
  • Mikaël Lindgren (13 collaborations)
  • Per Hammarström (12 collaborations)
  • Rubén Vidal (9 collaborations)

Nilsson regularly publishes in several scientific venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory) with 13 publications
  • Acta Neuropathologica Communications with 4 publications
  • ChemBioChem with 4 publications
  • Chemistry - A European Journal with 3 publications
  • ChemPhotoChem with 3 publications

Their research contributions predominantly lie at the intersection of neurodegenerative disease mechanisms and molecular biology techniques. This focus is evident in the exploration of protein misfolding, amyloid formation, and associated neurological pathologies in both Alzheimer's and Parkinson's disease contexts.

Best Publications

  • Chip and solution detection of DNA hybridization using a luminescent zwitterionic polythiophene derivative.

    K. Peter R. Nilsson;Olle Inganäs

  • Novel pentameric thiophene derivatives for in vitro and in vivo optical imaging of a plethora of protein aggregates in cerebral amyloidoses

    Andreas Åslund;Christina J. Sigurdson;Therése Klingstedt;Stefan Grathwohl

  • ApoE facilitates the microglial response to amyloid plaque pathology

    Jason D. Ulrich;Tyler K. Ulland;Thomas E. Mahan;Sofie Nyström

  • Prion strain discrimination using luminescent conjugated polymers.

    Christina J Sigurdson;K Peter R Nilsson;Simone Hornemann;Giuseppe Manco

  • Self-assembly of synthetic peptides control conformation and optical properties of a zwitterionic polythiophene derivative

    K. Peter R. Nilsson;Johan Rydberg;Lars Baltzer;Olle Inganäs

  • Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer’s disease

    Jay Rasmussen;Jay Rasmussen;Jasmin Mahler;Natalie Beschorner;Stephan A. Kaeser;Stephan A. Kaeser

  • Conjugated Polyelectrolytes: Conformation-Sensitive Optical Probes for Detection of Amyloid Fibril Formation†

    K. Peter R. Nilsson;Anna Herland;Per Hammarström;Olle Inganäs

  • Imaging distinct conformational states of amyloid-β fibrils in Alzheimer's disease using novel luminescent probes

    K. Peter R. Nilsson;Andreas Åslund;Ina Berg;Sofie Nyström

  • Synthesis of a library of oligothiophenes and their utilization as fluorescent ligands for spectral assignment of protein aggregates

    Therése Klingstedt;Andreas Åslund;Rozalyn A. Simon;Leif B. G. Johansson

  • Synthesis of a regioregular zwitterionic conjugated oligoelectrolyte, usable as an optical probe for detection of amyloid fibril formation at acidic pH

    Anna Herland;K Peter R Nilsson;Johan D M Olsson;Per Hammarström

  • A molecular switch controls interspecies prion disease transmission in mice

    Christina J. Sigurdson;K. Peter R. Nilsson;K. Peter R. Nilsson;Simone Hornemann;Simone Hornemann;Giuseppe Manco

  • Seeded strain-like transmission of β-amyloid morphotypes in APP transgenic mice.

    Götz Heilbronner;Götz Heilbronner;Yvonne S Eisele;Yvonne S Eisele;Franziska Langer;Franziska Langer;Stephan A Kaeser;Stephan A Kaeser

  • Conjugated polyelectrolytes--conformation-sensitive optical probes for staining and characterization of amyloid deposits.

    K. Peter R. Nilsson;K. Peter R. Nilsson;Per Hammarström;Fredrik Ahlgren;Anna Herland

  • Cellulose from the green macroalgae Ulva lactuca: isolation, characterization, optotracing, and production of cellulose nanofibrils

    Niklas Wahlström;Ulrica Edlund;Henrik Pavia;Gunilla Toth

  • Structure-based drug design identifies polythiophenes as antiprion compounds

    Uli S. Herrmann;Anne K. Schütz;Hamid Shirani;Danzhi Huang

  • Twisting macromolecular chains: self-assembly of a chiral supermolecule from nonchiral polythiophene polyanions and random-coil synthetic peptides.

    K. Peter R. Nilsson;Johan Rydberg;Lars Baltzer;Olle Inganäs

  • The Structural Basis for Optimal Performance of Oligothiophene‐Based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates

    Therése Klingstedt;Hamid Shirani;K. O. Andreas Åslund;Nigel J. Cairns

  • Small organic probes as amyloid specific ligands--past and recent molecular scaffolds.

    K. Peter R. Nilsson

  • Precisely Defined Conjugated Oligoelectrolytes for Biosensing and Therapeutics

    Bing Wang;Bridget N. Queenan;Shu Wang;K. Peter R. Nilsson

  • Evidence for age-dependent in vivo conformational rearrangement within Aβ amyloid deposits.

    Sofie Nyström;Katarzyna M. Psonka-Antonczyk;Pål Gunnar Ellingsen;Leif B. G. Johansson

  • A Fluorescent Pentameric Thiophene Derivative Detects in Vitro-Formed Prefibrillar Protein Aggregates

    Per Hammarström;Rozalyn Simon;Sofie Nyström;Peter Konradsson

Frequent Co-Authors

Christina J. Sigurdson
Christina J. Sigurdson University of California, San Diego
Olle Inganäs
Olle Inganäs Linköping University
Adriano Aguzzi
Adriano Aguzzi University of Zurich
Kaj Blennow
Kaj Blennow University of Gothenburg
Gunilla T. Westermark
Gunilla T. Westermark Uppsala University
Kurt Wüthrich
Kurt Wüthrich ETH Zurich
Matthias Staufenbiel
Matthias Staufenbiel University of Tübingen
Erik Portelius
Erik Portelius Sahlgrenska University Hospital

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