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Biology and Biochemistry

D-Index
93
Citations
31993
World Ranking
2103
National Ranking
148

Overview

Ernst Th. Rietschel is affiliated with the Institute for Advanced Sustainability Studies in Germany. Their research focuses predominantly within the field of Medicine, with extensive work in Pulmonary and Respiratory Medicine as well as Immunology and Allergy. Other notable subfields include Physiology, Pharmacology, and Epidemiology.

The scientist's research encompasses several main topics, including Food Allergy and Anaphylaxis Research, Asthma and respiratory diseases, Allergic Rhinitis and Sensitization, Cystic Fibrosis Research Advances, Respiratory and Cough-Related Research, Neonatal Respiratory Health Research, and Drug-Induced Adverse Reactions.

Their recent publications demonstrate active contributions to these areas. Key papers include:

  • Guideline (S2k) on acute therapy and management of anaphylaxis: 2021 update (2021), published in Allergo Journal International
  • T2-high asthma phenotypes across lifespan (2022), published in European Respiratory Journal
  • Impact of elexacaftor/tezacaftor/ivacaftor on lung function, nutritional status, pulmonary exacerbation frequency and sweat chloride in people with cystic fibrosis: real-world evidence from the German CF Registry (2023), published in The Lancet Regional Health - Europe
  • Leitlinie zu Akuttherapie und Management der Anaphylaxie - Update 2021 (2021), published in Allergo Journal
  • Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa (2023), published in Cell

Frequent collaborators in their work include Johannes Ring, Matthias Kopp, Silke van Koningsbruggen-Rietschel, Kirsten Beyer, and Ludger Klimek. The scientist has also published multiple papers in prominent venues such as:

  • Allergo Journal
  • Allergo Journal International
  • Research Square
  • European Respiratory Journal
  • Pneumologie

Best Publications

  • Bacterial endotoxin: molecular relationships of structure to activity and function.

    E T Rietschel;T Kirikae;F U Schade;U Mamat

  • Innate immune sensing and its roots: the story of endotoxin

    Bruce A Beutler;Ernst Th Rietschel

  • Bacterial lipopolysaccharides and innate immunity

    Christian Alexander;Ernst Th. Rietschel

  • Synthetic and natural Escherichia coli free lipid A express identical endotoxic activities

    Chris Galanos;Otto Lüderitz;Ernst Th. Rietschel;Otto Westphal

  • Bacterial endotoxin: Chemical constitution, biological recognition, host response, and immunological detoxification.

    E. T. Rietschel;H. Brade;O. Holst;L. Brade

  • Lipopolysaccharides of Gram-Negative Bacteria

    Otto Lüderitz;Marina A. Freudenberg;Chris Galanos;Volker Lehmann

  • Molecular mechanisms of endotoxin activity

    Jens Schletter;Holger Heine;Artur J. Ulmer;Ernst T. Rietschel

  • Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion

    Andra B. Schromm;Klaus Brandenburg;Harald Loppnow;Anthony P. Moran

  • A CFTR corrector (lumacaftor) and a CFTR potentiator (ivacaftor) for treatment of patients with cystic fibrosis who have a phe508del CFTR mutation: a phase 2 randomised controlled trial

    Michael P Boyle;Scott C Bell;Michael W Konstan;Susanna A McColley

  • Lipid A: chemical structure and biological activity.

    Otto Lüderitz;Chris Galanos;Volker Lehmann;Marjatta Nurminen

  • Allergy testing in children: why, who, when and how?

    A Høst;S Andrae;S Charkin;C Diaz-Vázquez

  • IL-1 induction-capacity of defined lipopolysaccharide partial structures.

    H Loppnow;H Brade;I Dürrbaum;C A Dinarello

  • Ataluren for the treatment of nonsense-mutation cystic fibrosis: a randomised, double-blind, placebo-controlled phase 3 trial

    Eitan Kerem;Michael W Konstan;Kris De Boeck;Frank J Accurso

  • Nature and linkages of the fatty acids present in the lipid-A component of Salmonella lipopolysaccharides.

    Ernst Th. Rietschel;Horst Gotter;Otto Lüderitz;Otto Westphal

  • Interaction of Lipopolysaccharides and Lipid A with Complement

    Chris Galanos;Ernst Th. Rietschel;Otto Lüderitz;Otto Westphal

  • The chemical structure of bacterial endotoxin in relation to bioactivity.

    Ernst Th. Rietschel;Teruo Kirikae;F. Ulrich Schade;Artur J. Ulmer

  • Molecular structure of lipid A, the endotoxic center of bacterial lipopolysaccharides.

    U Zähringer;B Lindner;E T Rietschel

  • Chemical structure of the lipopolysaccharide of Haemophilus influenzae strain I-69 Rd-/b+. Description of a novel deep-rough chemotype.

    Ilkka M. Helander;Buko Lindner;Helmut Brade;Klaus Altmann

  • Biological Activities of Lipid A Complexed with Bovine‐Serum Albumin

    Chris Galanos;Ernst T. Rietschel;Otto Lüderitz;Otto Westphal

  • Biochemistry and cell biology of bacterial endotoxins.

    Otto Holst;Artur J. Ulmer;Helmut Brade;Hans-Dieter Flad

Frequent Co-Authors

Ulrich Zähringer
Ulrich Zähringer Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Shoichi Kusumoto
Shoichi Kusumoto Osaka University
Helmut Brade
Helmut Brade BOKU University
Klaus Brandenburg
Klaus Brandenburg Leibniz Institute for Neurobiology
Hans-Dieter Flad
Hans-Dieter Flad Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Artur J. Ulmer
Artur J. Ulmer University of Freiburg
Chris Galanos
Chris Galanos Max Planck Society
Otto Westphal
Otto Westphal Max Planck Society
Ulrich Seydel
Ulrich Seydel Research Center Borstel - Leibniz-Center for Medicine and Biosciences
Tetsuo Shiba
Tetsuo Shiba Osaka University

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