What is he best known for?
The fields of study he is best known for:
His scientific interests lie mostly in Genetics, Gene, Genome, Human genome and Chromatin.
His work on Computational biology expands to the thematically related Genetics.
His research integrates issues of GENCODE and ENCODE in his study of Computational biology.
The Genomics research Yijun Ruan does as part of his general Genome study is frequently linked to other disciplines of science, such as Microbial metabolism and Microbial ecology, therefore creating a link between diverse domains of science.
His Human genome study combines topics from a wide range of disciplines, such as Histone H3, Histone, Cellular differentiation, H3K4me3 and Histone methylation.
His ChIA-PET research is multidisciplinary, relying on both ChIP-sequencing, Bivalent chromatin, Chromosome conformation capture, RNA polymerase II and Scaffold/matrix attachment region.
His most cited work include:
- Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project (4297 citations)
- Landscape of transcription in human cells (3260 citations)
- The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression. (3150 citations)
What are the main themes of his work throughout his whole career to date?
Yijun Ruan mostly deals with Genetics, Chromatin, Computational biology, Genome and Gene.
As part of his studies on Genetics, he often connects relevant subjects like Cell biology.
The various areas that Yijun Ruan examines in his Chromatin study include Enhancer, Chromosome conformation capture and Chromatin immunoprecipitation.
Yijun Ruan has included themes like Multiplex, ENCODE, DNA, Reference genome and Interactome in his Computational biology study.
He works mostly in the field of Genome, limiting it down to concerns involving genomic DNA and, occasionally, Insert.
His Human genome research is multidisciplinary, relying on both Evolutionary biology and RNA polymerase II.
He most often published in these fields:
- Genetics (67.01%)
- Chromatin (57.36%)
- Computational biology (52.28%)
What were the highlights of his more recent work (between 2019-2021)?
- Chromatin (57.36%)
- Genome (46.19%)
- Cell biology (12.69%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Chromatin, Genome, Cell biology, ChIA-PET and Biophysics.
His Chromatin study introduces a deeper knowledge of Gene.
When carried out as part of a general Genome research project, his work on Human genome is frequently linked to work in Random forest, therefore connecting diverse disciplines of study.
His Human genome research is multidisciplinary, incorporating elements of Structural variation, DNA sequencing, Reference genome and 1000 Genomes Project.
His Cell biology study integrates concerns from other disciplines, such as Inflammation and Gene expression.
His research investigates the connection with Biophysics and areas like Ultrastructure which intersect with concerns in Folding and In situ hybridization.
Between 2019 and 2021, his most popular works were:
- Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells (9 citations)
- Graph embedding and unsupervised learning predict genomic sub-compartments from HiC chromatin interaction data. (7 citations)
- A supervised learning framework for chromatin loop detection in genome-wide contact maps. (5 citations)
In his most recent research, the most cited papers focused on:
Yijun Ruan spends much of his time researching Chromatin, Genome, Cell biology, Ultrastructure and Human genome.
His Chromatin study frequently links to other fields, such as Epigenome.
His study connects Chromatin Loop and Genome.
Yijun Ruan interconnects Tumor necrosis factor alpha, CTCF, DNA, Zinc finger and Gene in the investigation of issues within Cell biology.
The concepts of his Ultrastructure study are interwoven with issues in Folding, Biophysics and In situ hybridization.
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