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Immunology

D-Index
69
Citations
23764
World Ranking
2473
National Ranking
1182

Overview

Aravinda M. de Silva is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research primarily falls within the field of Medicine, with a focus on several subfields including Infectious Diseases, Public Health, Environmental and Occupational Health, Molecular Biology, Epidemiology, and Obstetrics and Gynecology.

The scientist's work covers a range of topics related to infectious diseases, with prominent areas including mosquito-borne diseases and control, viral infections and vectors, SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, viral infections and outbreaks research, vaccines and immunoinformatics approaches, and malaria research and control.

Aravinda M. de Silva has contributed to multiple recent papers, including:

  • Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals (2020, Cell)
  • The receptor-binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients (2020, Science Immunology)
  • Zika virus infection enhances future risk of severe dengue disease (2020, Science)
  • Severe Dengue Epidemic, Sri Lanka, 2017 (2020, Emerging infectious diseases)
  • A tetravalent live attenuated dengue virus vaccine stimulates balanced immunity to multiple serotypes in humans (2021, Nature Communications)

Their frequent collaborators include Ralph S. Baric, Lakshmanane Premkumar, Ramesh Jadi, Alena J. Markmann, and Yixuan J. Hou.

The main publication venues for this scientist's work feature a wide spectrum of respected platforms, such as UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), mSphere, PLoS ONE, and Emerging infectious diseases.

Best Publications

  • Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals.

    Alba Grifoni;Daniela Weiskopf;Sydney I. Ramirez;Sydney I. Ramirez;Jose Mateus

  • SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract.

    Yixuan J. Hou;Kenichi Okuda;Caitlin E. Edwards;David R. Martinez

  • Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans.

    Jose Mateus;Alba Grifoni;Alison Tarke;John Sidney

  • SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

    Yixuan J. Hou;Shiho Chiba;Peter Halfmann;Camille Ehre

  • The receptor binding domain of the viral spike protein is an immunodominant and highly specific target of antibodies in SARS-CoV-2 patients.

    Lakshmanane Premkumar;Bruno Segovia-Chumbez;Ramesh Jadi;David R. Martinez

  • The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

    Martina Beltramello;Katherine L. Williams;Cameron P. Simmons;Annalisa Macagno

  • Comprehensive analysis of dengue virus-specific responses supports an HLA-linked protective role for CD8+ T cells

    Daniela Weiskopf;Michael A. Angelo;Elzinandes L. de Azeredo;John Sidney

  • Emergence and Global Spread of a Dengue Serotype 3, Subtype III Virus

    William B. Messer;Duane J. Gubler;Eva Harris;Kamalanayani Sivananthan

  • Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine.

    A M de Silva;S R Telford;L R Brunet;S W Barthold

  • Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions.

    Ruklanthi De Alwis;Scott A. Smith;Nicholas P. Olivarez;William B. Messer

  • The Human Antibody Response to Dengue Virus Infection

    Wahala M. P. B. Wahala;Aravinda M. de Silva

  • Antigenic and genetic heterogeneity of Borrelia burgdorferi populations transmitted by ticks.

    Jun Ohnishi;Joseph Piesman;Aravinda M. de Silva

  • Growth and migration of Borrelia burgdorferi in Ixodes ticks during blood feeding

    A M De Silva;E Fikrig

  • Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody

    W.M. P. B. Wahala;Annette A. Kraus;Laura B. Haymore;Mary Ann Accavitti-Loper

  • Dengue virus infection elicits highly polarized CX3CR1+ cytotoxic CD4+ T cells associated with protective immunity.

    Daniela Weiskopf;Derek J. Bangs;John Sidney;Ravi V. Kolla

  • Attachment of Borrelia burgdorferi within Ixodes scapularis mediated by outer surface protein A.

    Utpal Pal;Aravinda M. de Silva;Ruth R. Montgomery;Durland Fish

  • Zika virus infection enhances future risk of severe dengue disease

    Leah C. Katzelnick;César Narvaez;Sonia Arguello;Brenda Lopez Mercado

  • Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers

    Guntur Fibriansah;Kristie D. Ibarra;Thiam-Seng Ng;Scott A. Smith

  • In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection.

    Ruklanthi de Alwis;Martina Beltramello;William B. Messer;Soila Sukupolvi-Petty

  • Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus

    Petraleigh Pantoja;Erick X. Pérez-Guzmán;Idia V. Rodríguez;Laura J. White

  • A highly potent human antibody neutralizes dengue virus serotype 3 by binding across three surface proteins

    Guntur Fibriansah;Joanne L. Tan;Scott A. Smith;Ruklanthi De Alwis

Frequent Co-Authors

Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill
Eva Harris
Eva Harris University of California, Berkeley
Alessandro Sette
Alessandro Sette La Jolla Institute For Allergy & Immunology
Daniela Weiskopf
Daniela Weiskopf La Jolla Institute For Allergy & Immunology
James E. Crowe
James E. Crowe Vanderbilt University Medical Center
Boyd Yount
Boyd Yount University of North Carolina at Chapel Hill
Bjoern Peters
Bjoern Peters La Jolla Institute For Allergy & Immunology
Anna P. Durbin
Anna P. Durbin Johns Hopkins University
Benjamin J. Doranz
Benjamin J. Doranz University of Pennsylvania
John Sidney
John Sidney La Jolla Institute For Allergy & Immunology

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