World's Best Scientists 2026 revealed!

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Microbiology

D-Index
85
Citations
25241
World Ranking
879
National Ranking
406

Overview

Benhur Lee is affiliated with the Icahn School of Medicine at Mount Sinai in the United States and has contributed extensively to research in the field of medicine, with a particular focus on infectious diseases and epidemiology. Their work encompasses molecular biology, immunology, and genetics, with a strong emphasis on viral infections and respiratory diseases.

The scientist's research topics include:

  • SARS-CoV-2 and COVID-19 Research
  • Virology and Viral Diseases
  • COVID-19 Clinical Research Studies
  • Viral Infections and Vectors
  • Respiratory viral infections research
  • Animal Virus Infections Studies
  • Mosquito-borne diseases and control

Benhur Lee has published numerous papers in top-tier journals and preprint platforms. Some recent notable publications include:

  • Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis, 2021, Nature
  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection, 2020, Cell
  • SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species, 2020, Emerging Microbes & Infections
  • Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • The Impact of Evolving SARS-CoV-2 Mutations and Variants on COVID-19 Vaccines, 2022, mBio

The scientist frequently collaborates with several coauthors, including:

  • Christian S. Stevens
  • Kasopefoluwa Y. Oguntuyo
  • Shreyas Kowdle
  • Chuan-Tien Hung
  • Satoshi Ikegame

Benhur Lee is a regular contributor to multiple publication venues, highlighting a broad publishing record in the scientific community. Key venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Virology
  • mBio
  • PLoS Pathogens
  • Nature Microbiology

Their expertise is grounded in extensive experience in infectious diseases and the molecular mechanisms underlying viral pathogenesis, which informs ongoing studies in SARS-CoV-2 biology and related fields. This work contributes to understanding viral infection mechanisms, host-pathogen interactions, and implications for vaccine development and disease management.

Best Publications

  • Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages.

    Benhur Lee;Matthew Sharron;Luis J. Montaner;Drew Weissman

  • Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.

    Su Yang Liu;Roghiyh Aliyari;Kelechi Chikere;Guangming Li

  • Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.

    Bryan A. Johnson;Xuping Xie;Adam L. Bailey;Birte Kalveram

  • EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus.

    Oscar A. Negrete;Ernest L. Levroney;Hector C. Aguilar;Andrea Bertolotti-Ciarlet

  • Constitutive and induced expression of DC-SIGN on dendritic cell and macrophage subpopulations in situ and in vitro.

    Elizabeth J. Soilleux;Lesley S. Morris;George Leslie;Jihed Chehimi

  • GENETIC ACCELERATION OF AIDS PROGRESSION BY A PROMOTER VARIANT OF CCR5

    Maureen P. Martin;Michael Dean;Michael W. Smith;Cheryl Winkler

  • The Three-Dimensional Structure of Ribonuclease-S INTERPRETATION OF AN ELECTRON DENSITY MAP AT A NOMINAL RESOLUTION OF 2 A

    H.W. Wyckoff;D. Tsernoglou;A.W. Hanson;J.R. Knox

  • Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.

    Jin Wei;Mia Madel Alfajaro;Peter C. DeWeirdt;Ruth E. Hanna

  • Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function.

    Benhur Lee;Benhur Lee;Matthew Sharron;Cedric Blanpain;Benjamin J. Doranz

  • DC-SIGNR, a DC-SIGN homologue expressed in endothelial cells, binds to human and simian immunodeficiency viruses and activates infection in trans.

    Stefan Pöhlmann;Elizabeth J. Soilleux;Frédéric Baribaud;George J. Leslie

  • Utilization of chemokine receptors, orphan receptors, and herpesvirus-encoded receptors by diverse human and simian immunodeficiency viruses.

    Joseph Rucker;Aimee L. Edinger;Matthew Sharron;Michel Samson

  • Taxonomy of the order Mononegavirales: update 2018

    Gaya K. Amarasinghe;Nidia G. Aréchiga Ceballos;Ashley C. Banyard;Christopher F. Basler

  • ICTV Virus Taxonomy Profile: Pneumoviridae.

    Bert Rima;Peter Collins;Andrew Easton;Ron Fouchier

  • Two key residues in ephrinB3 are critical for its use as an alternative receptor for Nipah virus.

    Oscar A Negrete;Mike C Wolf;Hector C. Aguilar;Sven G. Enterlein

  • MicroRNA profiling identifies miR-34a and miR-21 and their target genes JAG1 and WNT1 in the coordinate regulation of dendritic cell differentiation

    Sara T. Hashimi;Jennifer A. Fulcher;Margaret H. Chang;Lanny Gov

  • Microglia Express CCR5, CXCR4, and CCR3, but of These, CCR5 Is the Principal Coreceptor for Human Immunodeficiency Virus Type 1 Dementia Isolates

    Andrew V. Albright;Joseph T. C. Shieh;Takayuki Itoh;Benhur Lee

  • CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist.

    Cédric Blanpain;Isabelle Migeotte;Isabelle Migeotte;Benhur Lee;Benhur Lee;Jalal Vakili;Jalal Vakili

  • Taxonomy of the order Mononegavirales: update 2019.

    Gaya K. Amarasinghe;María A. Ayllón;Yīmíng Bào;Christopher F. Basler

  • CD4-independent, CCR5-dependent infection of brain capillary endothelial cells by a neurovirulent simian immunodeficiency virus strain

    Aimee L. Edinger;Joseph L. Mankowski;Benjamin J. Doranz;Barry J. Margulies

  • ICTV Virus Taxonomy Profile: Paramyxoviridae.

    Bert Rima;Anne Balkema-Buschmann;William G Dundon;Paul Duprex

  • DC-SIGN Interactions with Human Immunodeficiency Virus Type 1 and 2 and Simian Immunodeficiency Virus

    Stefan Pöhlmann;Frédéric Baribaud;Benhur Lee;George J. Leslie

  • Taxonomy of the order Mononegavirales: update 2017

    Gaya K. Amarasinghe;Yīmíng Bào;Christopher F. Basler;Sina Bavari

Frequent Co-Authors

Robert W. Doms
Robert W. Doms Children's Hospital of Philadelphia
Paul R. Gorry
Paul R. Gorry RMIT University
Alexander N. Freiberg
Alexander N. Freiberg The University of Texas Medical Branch at Galveston
Sharon R. Lewin
Sharon R. Lewin University of Melbourne
Lin-Fa Wang
Lin-Fa Wang Duke NUS Graduate Medical School
Norbert Nowotny
Norbert Nowotny University of Veterinary Medicine Vienna
Linda G. Baum
Linda G. Baum University of California, Los Angeles
Marc Parmentier
Marc Parmentier Université Libre de Bruxelles
Michael E. Jung
Michael E. Jung University of California, Los Angeles
Andrew J. Easton
Andrew J. Easton University of Warwick

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