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Microbiology

D-Index
45
Citations
9200
World Ranking
4976
National Ranking
1929

Overview

Alexander N. Freiberg is affiliated with The University of Texas Medical Branch at Galveston in the United States. Their research primarily focuses on medicine, with a significant emphasis on infectious diseases, epidemiology, immunology, public health, environmental and occupational health, and molecular biology.

Their work extensively covers topics including:

  • Viral Infections and Vectors
  • Virology and Viral Diseases
  • Viral Infections and Outbreaks Research
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Interferon and Immune Responses
  • Mosquito-borne Diseases and Control

Alexander N. Freiberg has contributed to several recent research papers, including:

  • Spike mutation D614G alters SARS-CoV-2 fitness, 2020, Nature
  • Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis, 2021, Nature
  • SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species, 2020, Emerging Microbes & Infections
  • Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility, 2020, bioRxiv (Cold Spring Harbor Laboratory)

Frequent co-authors collaborating with Freiberg include:

  • Terry L. Juelich
  • Birte Kalveram
  • Benhur Lee
  • Lihong Zhang
  • Pei-Yong Shi

Alexander N. Freiberg's studies have appeared regularly in diverse publication venues such as:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Viruses
  • Antiviral Research
  • Nature

Best Publications

  • Spike mutation D614G alters SARS-CoV-2 fitness.

    Jessica A. Plante;Yang Liu;Jianying Liu;Hongjie Xia

  • Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.

    Su Yang Liu;Roghiyh Aliyari;Kelechi Chikere;Guangming Li

  • Loss of furin cleavage site attenuates SARS-CoV-2 pathogenesis.

    Bryan A. Johnson;Xuping Xie;Adam L. Bailey;Birte Kalveram

  • SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.

    Mehdi Moustaqil;Emma Ollivier;Hsin Ping Chiu;Sarah Van Tol

  • Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus

    Mohammad F. Saeed;Andrey A. Kolokoltsov;Alexander N. Freiberg;Michael R. Holbrook

  • Furin Cleavage Site Is Key to SARS-CoV-2 Pathogenesis

    Bryan A. Johnson;Xuping Xie;Birte Kalveram;Kumari G. Lokugamage

  • Evidence for henipavirus spillover into human populations in Africa.

    Olivier Pernet;Bradley S. Schneider;Shannon M. Beaty;Matthew Lebreton

  • ISG15 deficiency and increased viral resistance in humans but not mice.

    Scott D. Speer;Zhi Li;Sofija Buta;Béatrice Payelle-Brogard

  • Ubiquitin-Regulated Nuclear-Cytoplasmic Trafficking of the Nipah Virus Matrix Protein Is Important for Viral Budding

    Yao E. Wang;Arnold Park;Michael Lake;Mickey Pentecost

  • Favipiravir (T-705) protects against Nipah virus infection in the hamster model.

    Brian E. Dawes;Birte Kalveram;Tetsuro Ikegami;Terry Juelich

  • Three-Dimensional Organization of Rift Valley Fever Virus Revealed by Cryoelectron Tomography

    Alexander N. Freiberg;Michael B. Sherman;Marc C. Morais;Michael R. Holbrook

  • Combined chloroquine and ribavirin treatment does not prevent death in a hamster model of Nipah and Hendra virus infection.

    Alexander N. Freiberg;Melissa N. Worthy;Benhur Lee;Benhur Lee;Michael R. Holbrook

  • T-705 (Favipiravir) Inhibition of Arenavirus Replication in Cell Culture

    Michelle Mendenhall;Andrew Russell;Terry Juelich;Emily L. Messina

  • Single-particle cryo-electron microscopy of Rift Valley fever virus.

    Michael B. Sherman;Alexander N. Freiberg;Michael R. Holbrook;Stanley J. Watowich

  • A Mechanistic Paradigm for Broad-Spectrum Antivirals that Target Virus-Cell Fusion

    Frederic Vigant;Jihye Lee;Axel Hollmann;Lukas B. Tanner

  • An Intersubunit Active Site between Supercoiled Parallel Beta Helices in the Trimeric Tailspike Endorhamnosidase of Shigella Flexneri Phage Sf6.

    Jürgen J. Müller;Stefanie Barbirz;Karolin Heinle;Alexander Freiberg

  • The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response.

    Preeti Bharaj;Yao E. Wang;Brian E. Dawes;Tatyana E. Yun

  • The Lack of Maturation of Ebola Virus-Infected Dendritic Cells Results from the Cooperative Effect of at Least Two Viral Domains

    Ndongala M. Lubaki;Philipp Ilinykh;Philipp Ilinykh;Colette Pietzsch;Colette Pietzsch;Bersabeh Tigabu;Bersabeh Tigabu

  • Inactivated or Live-Attenuated Bivalent Vaccines That Confer Protection against Rabies and Ebola Viruses

    Joseph E. Blaney;Christoph Wirblich;Amy B. Papaneri;Reed F. Johnson

  • The Host E3-Ubiquitin Ligase TRIM6 Ubiquitinates the Ebola Virus VP35 Protein and Promotes Virus Replication.

    Preeti Bharaj;Colm Atkins;Priya Luthra;Maria Isabel Giraldo

  • A Replication-incompetent Rift Valley Fever Vaccine: Chimeric Virus-like Particles Protect Mice and Rats Against Lethal Challenge

    Robert B. Mandell;Ramesh Koukuntla;Laura J.K. Mogler;Andrea K. Carzoli

  • Spike mutation D614G alters SARS-CoV-2 fitness and neutralization susceptibility.

    Jessica A Plante;Yang Liu;Jianying Liu;Hongjie Xia

Frequent Co-Authors

Benhur Lee
Benhur Lee Icahn School of Medicine at Mount Sinai
Michael R. Holbrook
Michael R. Holbrook National Institutes of Health
Vineet D. Menachery
Vineet D. Menachery The University of Texas Medical Branch at Galveston
Scott C. Weaver
Scott C. Weaver The University of Texas Medical Branch at Galveston
Alexander Bukreyev
Alexander Bukreyev The University of Texas Medical Branch at Galveston
Jing Zou
Jing Zou The University of Texas Medical Branch at Galveston
Xuping Xie
Xuping Xie The University of Texas Medical Branch at Galveston
Pei-Yong Shi
Pei-Yong Shi GlaxoSmithKline (United Kingdom)
Ayato Takada
Ayato Takada Hokkaido University
Zhiqiang An
Zhiqiang An The University of Texas Health Science Center at Houston

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