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Antonella Caccamo

Antonella Caccamo

D-Index & Metrics

Neuroscience

D-Index
39
Citations
15613
World Ranking
8196
National Ranking
447

Overview

Antonella Caccamo is affiliated with the University of Messina in Italy and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans multiple subfields, including Molecular Biology, Neurology, Physiology, Epidemiology, and Biological Psychiatry.

Their work primarily focuses on the following topics:

  • Alzheimer's disease research and treatments
  • Amyotrophic Lateral Sclerosis Research
  • Autophagy in Disease and Therapy
  • Tryptophan and brain disorders
  • Bacteriophages and microbial interactions
  • CRISPR and Genetic Engineering
  • Parkinson's Disease Mechanisms and Treatments

Antonella Caccamo's frequent co-authors include:

  • Salvatore Oddo
  • Laura Maria De Plano
  • Sabrina Conoci
  • Andrea Magrì
  • Francesca Guarino

They have published research in several recurrent scientific venues, with multiple contributions to:

  • Cells
  • Biomolecules
  • International Journal of Molecular Sciences
  • Biology
  • Journal of Alzheimer's Disease

Some of the recent papers associated with their work are:

  • The Role of the Transcription Factor Nrf2 in Alzheimer's Disease: Therapeutic Opportunities (2023), Biomolecules
  • Applications of CRISPR-Cas9 in Alzheimer's Disease and Related Disorders (2022), International Journal of Molecular Sciences
  • Epigenetic Changes in Alzheimer's Disease: DNA Methylation and Histone Modification (2024), Cells
  • ERK1/2-dependent TSPO overactivation associates with the loss of mitophagy and mitochondrial respiration in ALS (2023), Cell Death and Disease
  • Small Hexokinase 1 Peptide against Toxic SOD1 G93A Mitochondrial Accumulation in ALS Rescues the ATP-Related Respiration (2021), Biomedicines

Best Publications

  • Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles: Intracellular Aβ and Synaptic Dysfunction

    Salvatore Oddo;Antonella Caccamo;Jason D. Shepherd;M. Paul Murphy

  • Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.

    Salvatore Oddo;Antonella Caccamo;Masashi Kitazawa;Bertrand P. Tseng

  • Molecular Interplay between Mammalian Target of Rapamycin (mTOR), Amyloid-β, and Tau EFFECTS ON COGNITIVE IMPAIRMENTS

    Antonella Caccamo;Smita Majumder;Arlan Richardson;Arlan Richardson;Randy Strong;Randy Strong

  • Temporal profile of amyloid-β (Aβ) oligomerization in an in vivo model of Alzheimer disease: A link between Aβ and tau pathology

    Salvatore Oddo;Antonella Caccamo;Levina Tran;Mary P. Lambert

  • M1 Receptors Play a Central Role in Modulating AD-like Pathology in Transgenic Mice

    Antonella Caccamo;Salvatore Oddo;Lauren M. Billings;Kim N. Green

  • Necroptosis activation in Alzheimer's disease

    Antonella Caccamo;Caterina Branca;Ignazio S. Piras;Eric Ferreira

  • mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.

    Antonella Caccamo;Andrea Magrì;David X. Medina;Elena V. Wisely

  • Reduction of Soluble Aβ and Tau, but Not Soluble Aβ Alone, Ameliorates Cognitive Decline in Transgenic Mice with Plaques and Tangles

    Salvatore Oddo;Vitaly Vasilevko;Antonella Caccamo;Masashi Kitazawa

  • Age- and region-dependent alterations in Aβ-degrading enzymes: implications for Aβ-induced disorders

    Antonella Caccamo;Salvatore Oddo;Michael C. Sugarman;Yama Akbari

  • Dysregulated IP3 Signaling in Cortical Neurons of Knock-In Mice Expressing an Alzheimer's-Linked Mutation in Presenilin1 Results in Exaggerated Ca2+ Signals and Altered Membrane Excitability

    Grace E. Stutzmann;Antonella Caccamo;Frank M. LaFerla;Ian Parker

  • Enhanced ryanodine receptor recruitment contributes to Ca2+ disruptions in young, adult, and aged Alzheimer's disease mice.

    Grace E. Stutzmann;Grace E. Stutzmann;Ian Smith;Antonella Caccamo;Salvatore Oddo

  • Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice.

    Lani K. Clinton;Lauren M. Billings;Kim N. Green;Antonella Caccamo

  • A Dynamic Relationship between Intracellular and Extracellular Pools of Aβ

    Salvatore Oddo;Antonella Caccamo;Ian F. Smith;Kim N. Green

  • Temporal and regional progression of Alzheimer's disease-like pathology in 3xTg-AD mice.

    Ramona Belfiore;Ramona Belfiore;Alexis Rodin;Eric Ferreira;Ramon Velazquez

  • CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

    Antonella Caccamo;Monica A. Maldonado;Alex F. Bokov;Smita Majumder

  • Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease

    Salvatore Oddo;Antonella Caccamo;Kim N. Green;Kevin Liang

  • Methylene Blue Reduces Aβ Levels and Rescues Early Cognitive Deficit by Increasing Proteasome Activity

    David X. Medina;Antonella Caccamo;Salvatore Oddo

  • Lithium Reduces Tau Phosphorylation but Not Aβ or Working Memory Deficits in a Transgenic Model with Both Plaques and Tangles

    Antonella Caccamo;Salvatore Oddo;Lana X. Tran;Frank M. LaFerla

  • Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling.

    Smita Majumder;Antonella Caccamo;David X. Medina;Adriana D. Benavides

  • Naturally Secreted Amyloid-β Increases Mammalian Target of Rapamycin (mTOR) Activity via a PRAS40-mediated Mechanism

    Antonella Caccamo;Monica A. Maldonado;Smita Majumder;David X. Medina

  • CBP gene transfer increases BDNF levels and ameliorates learning and memory deficits in a mouse model of Alzheimer's disease

    Antonella Caccamo;Salvatore Oddo

Frequent Co-Authors

Salvatore Oddo
Salvatore Oddo Arizona State University
Kim N. Green
Kim N. Green University of California, Irvine
Abraham Fisher
Abraham Fisher Israel Institute for Biological Research
James L. McGaugh
James L. McGaugh University of California, Irvine
Frances M. Leslie
Frances M. Leslie University of California, Irvine
Mark P. Mattson
Mark P. Mattson Johns Hopkins University
Raju Metherate
Raju Metherate University of California, Irvine
William L. Klein
William L. Klein Northwestern University
Todd E. Golde
Todd E. Golde Emory University
Alcino J. Silva
Alcino J. Silva University of California, Los Angeles

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