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Ekambar R. Kandimalla

Ekambar R. Kandimalla

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
8008
World Ranking
15302
National Ranking
6382

Overview

Ekambar R. Kandimalla is affiliated with Takeda in the United States. Their research focuses primarily on Medicine and Engineering, with specific attention to Oncology, Biomedical Engineering, and Radiology, Nuclear Medicine and Imaging as subfields of study.

Their scholarly work centers on topics including Cancer Immunotherapy and Biomarkers, Nanoplatforms for cancer theranostics, and Radiopharmaceutical Chemistry and Applications.

Ekambar R. Kandimalla has published at least one paper titled Abstract 1706: Hydrogel encapsulated TLR9 agonists show sustained tumor growth inhibition and prolong survival of CT26 tumor-bearing mice in 2021, appearing in the journal Cancer Research.

  • Jun Jiang
  • Lokendrakumar C. Bengani
  • Xinyu Huang
  • Jason Zhang

  • Cancer Research

Best Publications

  • Antisense therapeutics: is it as simple as complementary base recognition?

    Sudhir Agrawal;Ekambar R Kandimalla

  • Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics.

    Dan C McManus;Charles A Lefebvre;Gabriele Cherton-Horvat;Martine St-Jean

  • Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles

    Ekambar R. Kandimalla;Lakshmi Bhagat;Daqing Wang;Dong Yu

  • Modulation of Immunostimulatory Properties of Oligonucleotide-Based Compounds by Optimal Presentation of 5' Ends

    Sudhir Agrawal;Ekambar R. Kandimalla;Dong Yu;Lakshmi Bhagat

  • Immunomodulatory oligonucleotides containing a cytosine-phosphate-2′-deoxy-7-deazaguanosine motif as potent Toll-like receptor 9 agonists

    Ekambar R. Kandimalla;Lakshmi Bhagat;Yukui Li;Dong Yu

  • Preclinical Characterization of AEG35156/GEM 640, a Second-Generation Antisense Oligonucleotide Targeting X-Linked Inhibitor of Apoptosis

    Eric C. LaCasse;Gabriele G. Cherton-Horvat;Kimberley E. Hewitt;Lori J. Jerome

  • Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships.

    Ekambar R Kandimalla;Dong Yu;Qiuyan Zhao;Sudhir Agrawal

  • Antisense and siRNA as agonists of Toll-like receptors

    Sudhir Agrawal;Ekambar R Kandimalla

  • Inhibition of 14q32 MicroRNAs miR-329, miR-487b, miR-494 and miR-495 Increases Neovascularization and Blood Flow Recovery after Ischemia

    Sabine M.J. Welten;Antonius J.N.M. Bastiaansen;Rob C.M. de Jong;Margreet R. de Vries

  • Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways.

    Sai Latha Shankar;Sridhar Mani;Kathleen Norman O'Guin;Ekambar R. Kandimalla

  • Conjugation of ligands at the 5'-end of CpG DNA affects immunostimulatory activity.

    Ekambar R Kandimalla;Lakshmi Bhagat;Dong Yu;Yan-Ping Cong

  • Medicinal chemistry and therapeutic potential of CpG DNA

    Sudhir Agrawal;Ekambar R Kandimalla

  • Accessible 5'-end of CpG-containing phosphorothioate oligodeoxynucleotides is essential for immunostimulatory activity.

    Dong Yu;Qiuyan Zhao;Ekambar R Kandimalla;Sudhir Agrawal

  • Antisense and/or immunostimulatory oligonucleotide therapeutics.

    S Agrawal;E R Kandimalla

  • Secondary structures in CpG oligonucleotides affect immunostimulatory activity.

    Ekambar R Kandimalla;Lakshmi Bhagat;Yan-Ping Cong;Rajendra K Pandey

  • CpG penta- and hexadeoxyribonucleotides as potent immunomodulatory agents.

    Lakshmi Bhagat;Fu Gang Zhu;Dong Yu;Jimmy Tang

  • Design, synthesis and biological evaluation of novel antagonist compounds of Toll-like receptors 7, 8 and 9

    Ekambar R. Kandimalla;Lakshmi Bhagat;Daqing Wang;Dong Yu

  • Pseudo-cyclic oligonucleobases

    Sudhir Agrawal;Ekambar R. Kandimalla

  • Stereo-enriched phosphorothioate oligodeoxynucleotides: synthesis, biophysical and biological properties.

    Dong Yu;Ekambar R. Kandimalla;Allysen Roskey;Qiuyan Zhao

  • Mixed backbone antisense oligonucleotides containing 2'-5'-ribonucleotide- and 3'-5'-deoxyribonucleotides segments

    Ekambar R. Kandimalla;Sudhir Agrawal

Frequent Co-Authors

Sudhir Agrawal
Sudhir Agrawal University of Massachusetts Chan Medical School
Hui Wang
Hui Wang Chinese Academy of Sciences
Paul H.A. Quax
Paul H.A. Quax Leiden University Medical Center
Johan Kuiper
Johan Kuiper Leiden University
Devendra K. Agrawal
Devendra K. Agrawal Western University of Health Sciences
Giampaolo Tortora
Giampaolo Tortora University of Verona
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Markus H. Heim
Markus H. Heim University Hospital of Basel
Gennaro Ciliberto
Gennaro Ciliberto Magna Graecia University
Danilo R. Casimiro
Danilo R. Casimiro United States Military Academy

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