World's Best Scientists 2026 revealed!

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Immunology

D-Index
130
Citations
68571
World Ranking
229
National Ranking
150

Medicine

D-Index
130
Citations
68808
World Ranking
2481
National Ranking
1399

Overview

Arthur M. Krieg is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research primarily focuses on the fields of Medicine and Immunology and Microbiology, with significant contributions to Oncology, Immunology, and Molecular Biology.

The main topics addressed in their work include Cancer Immunotherapy and Biomarkers, CAR-T cell therapy research, Immunotherapy and Immune Responses, Immune Response and Inflammation, RNA Interference and Gene Delivery, CRISPR and Genetic Engineering, and DNA and Nucleic Acid Chemistry.

The scientist has an extensive publication record in several venues. Frequent publication venues include:

  • Regular and Young Investigator Award Abstracts
  • Cancer Research
  • Nucleic Acid Therapeutics
  • Cancer Cell
  • The Journal of Immunology

Frequent coauthors who have collaborated with Arthur M. Krieg are:

  • James E. Wooldridge
  • Diwakar Davar
  • Riyue Bao
  • Dmitri Bobilev
  • Jason J. Luke

Selected recent papers by Arthur M. Krieg include:

  • Considerations in the Preclinical Assessment of the Safety of Antisense Oligonucleotides, 2022, Nucleic Acid Therapeutics
  • Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization, 2020, The Journal of Immunology
  • Neoadjuvant vidutolimod and nivolumab in high-risk resectable melanoma: A prospective phase II trial, 2024, Cancer Cell
  • Intratumoral injection of CMP-001, a toll-like receptor 9 (TLR9) agonist, in combination with pembrolizumab reversed programmed death receptor 1 (PD-1) blockade resistance in advanced melanoma, 2020, Regular and Young Investigator Award Abstracts
  • Durable responses in anti-PD-1 refractory melanoma following intratumoral injection of a toll-like receptor 9 (TLR9) agonist, CMP-001, in combination with pembrolizumab, 2020, Oral Presentations

Best Publications

  • CPG MOTIFS IN BACTERIAL DNA TRIGGER DIRECT B-CELL ACTIVATION

    Arthur M. Krieg;Ae-Kyung Yi;Sara Matson;Thomas J. Waldschmidt

  • CpG Motifs in Bacterial DNA and Their Immune Effects

    Arthur M Krieg

  • Therapeutic potential of Toll-like receptor 9 activation

    Arthur M. Krieg

  • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

    Dennis M. Klinman;Ae-Kyung Yi;Serge L. Beaucage;Jacqueline Conover

  • CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.

    Rose S. Chu;Oleg S. Targoni;Arthur M. Krieg;Paul V. Lehmann

  • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

    Marion Jurk;Florian Heil;Jörg Vollmer;Christian Schetter

  • Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells

    Anne Krug;Simon Rothenfusser;Veit Hornung;Bernd Jahrsdörfer

  • Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.

    Z K Ballas;W L Rasmussen;A M Krieg

  • Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.

    Anne Krug;Andreas Towarowski;Stefanie Britsch;Simon Rothenfusser

  • CpG DNA Is a Potent Enhancer of Specific Immunity in Mice Immunized with Recombinant Hepatitis B Surface Antigen

    Heather L. Davis;Risini Weeranta;Thomas J. Waldschmidt;Lorraine Tygrett

  • CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells.

    G. Hartmann;G. J. Weiner;A. M. Krieg

  • Mechanism and Function of a Newly Identified CpG DNA Motif in Human Primary B Cells

    Gunther Hartmann;Arthur M. Krieg;Arthur M. Krieg

  • Delineation of a CpG Phosphorothioate Oligodeoxynucleotide for Activating Primate Immune Responses In Vitro and In Vivo

    Gunther Hartmann;Risini D. Weeratna;Zuhair K. Ballas;Zuhair K. Ballas;Paul Payette

  • Human Plasmacytoid Dendritic Cells Activated by CpG Oligodeoxynucleotides Induce the Generation of CD4+CD25+ Regulatory T Cells

    E. Ashley Moseman;Xueqing Liang;Amanda J. Dawson;Angela Panoskaltsis-Mortari

  • Immunostimulatory nucleic acid molecules

    Arthur M. Krieg;Joel N. Kline;Dennis Klinman;Alfred D. Steinberg

  • Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists.

    Jörg Vollmer;Arthur M. Krieg

  • Rapid and strong human CD8 + T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909

    Daniel E. Speiser;Danielle Liénard;Nathalie Rufer;Verena Rubio-Godoy

  • Characterization of three CpG oligodeoxynucleotide classes with distinct immunostimulatory activities

    Jörg Vollmer;Risini Weeratna;Paul Payette;Marion Jurk

  • Cutting Edge: Modulation of Airway Inflammation by CpG Oligodeoxynucleotides in a Murine Model of Asthma

    Joel N. Kline;Thomas J. Waldschmidt;Thomas R. Businga;Jennifer E. Lemish

  • Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

    George J. Weiner;Hsin-Ming Liu;James E. Wooldridge;Christopher E. Dahle

Frequent Co-Authors

Heather L. Davis
Heather L. Davis Sanofi (France)
George J. Weiner
George J. Weiner University of Iowa
Alfred D. Steinberg
Alfred D. Steinberg Mitre (United States)
Gunther Hartmann
Gunther Hartmann University Hospital Bonn
Grayson B. Lipford
Grayson B. Lipford Janus Biotherapeutics (United States)
Zuhair K. Ballas
Zuhair K. Ballas University of Iowa
Lorne A. Babiuk
Lorne A. Babiuk University of Alberta
George Mutwiri
George Mutwiri University of Saskatchewan
John M. Kirkwood
John M. Kirkwood University of Pittsburgh
Bruce R. Blazar
Bruce R. Blazar University of Minnesota

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