D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 123 Citations 53,534 276 World Ranking 104 National Ranking 72
Medicine D-index 128 Citations 58,904 310 World Ranking 1080 National Ranking 647

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cancer

His primary scientific interests are in CpG site, CpG Oligodeoxynucleotide, Immune system, Molecular biology and Immunology. His CpG site study incorporates themes from In vitro, Oligonucleotide, DNA, Adjuvant and DNA vaccination. His work deals with themes such as Toll-Like Receptor 9, T cell, B cell, TLR9 and Cytokine secretion, which intersect with CpG Oligodeoxynucleotide.

His work investigates the relationship between Immune system and topics such as Cancer research that intersect with problems in Cancer immunotherapy. Arthur M. Krieg combines subjects such as Cytokine, Interleukin 12, Lytic cycle, Kinase and In vivo with his study of Molecular biology. His Immunology study integrates concerns from other disciplines, such as Cytotoxic T cell, DNA methylation and Virology.

His most cited work include:

  • CPG MOTIFS IN BACTERIAL DNA TRIGGER DIRECT B-CELL ACTIVATION (3415 citations)
  • CpG Motifs in Bacterial DNA and Their Immune Effects (2260 citations)
  • CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma (1479 citations)

What are the main themes of his work throughout his whole career to date?

Arthur M. Krieg mainly focuses on CpG site, Immune system, Immunology, CpG Oligodeoxynucleotide and Molecular biology. Arthur M. Krieg has researched CpG site in several fields, including Nucleic acid, Oligonucleotide, DNA, Adjuvant and Innate immune system. His research integrates issues of Cancer research, Cytokine, Antigen and Cell biology in his study of Immune system.

Arthur M. Krieg interconnects TLR9 and Virology in the investigation of issues within Immunology. His study in CpG Oligodeoxynucleotide is interdisciplinary in nature, drawing from both Toll-Like Receptor 9, Immunity, Peripheral blood mononuclear cell, Cytokine secretion and Cytotoxic T cell. His research investigates the link between Molecular biology and topics such as In vivo that cross with problems in In vitro.

He most often published in these fields:

  • CpG site (73.04%)
  • Immune system (51.80%)
  • Immunology (44.80%)

What were the highlights of his more recent work (between 2008-2021)?

  • Immunology (44.80%)
  • Immune system (51.80%)
  • CpG site (73.04%)

In recent papers he was focusing on the following fields of study:

Arthur M. Krieg focuses on Immunology, Immune system, CpG site, CpG Oligodeoxynucleotide and Oligonucleotide. His studies deal with areas such as Cancer and Virology as well as Immunology. His Immune system study combines topics in areas such as Adjuvant, Cancer research and In vivo.

In his study, Potency is inextricably linked to Nucleic acid, which falls within the broad field of CpG site. His CpG Oligodeoxynucleotide research also works with subjects such as

  • TLR9 which intersects with area such as Toll-Like Receptor 9, Agonist and Immunity,
  • Receptor that connect with fields like Cell biology. His research in Cell biology tackles topics such as TLR7 which are related to areas like Molecular biology.

Between 2008 and 2021, his most popular works were:

  • Immunotherapeutic applications of CpG oligodeoxynucleotide TLR9 agonists. (411 citations)
  • Cancer and inflammation: Promise for biologic therapy (253 citations)
  • FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga. (170 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

Arthur M. Krieg spends much of his time researching Immunology, CpG Oligodeoxynucleotide, Immune system, Innate immune system and Cytokine. His research investigates the connection with Immunology and areas like Virology which intersect with concerns in Bacterial vaccine, Sepsis, Burkholderia pseudomallei, Biodefense and Melioidosis. His CpG Oligodeoxynucleotide research includes themes of Vaccination and CpG site.

His study focuses on the intersection of CpG site and fields such as Receptor with connections in the field of Cell biology, Cytosol and Intracellular parasite. His biological study spans a wide range of topics, including Human leukocyte antigen and In vivo. The concepts of his Innate immune system study are interwoven with issues in Inflammation, TLR9 and Toll-Like Receptor 9.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

CPG MOTIFS IN BACTERIAL DNA TRIGGER DIRECT B-CELL ACTIVATION

Arthur M. Krieg;Ae-Kyung Yi;Sara Matson;Thomas J. Waldschmidt.
Nature (1995)

4464 Citations

CpG Motifs in Bacterial DNA and Their Immune Effects

Arthur M Krieg.
Annual Review of Immunology (2002)

3085 Citations

CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gamma

Dennis M. Klinman;Ae-Kyung Yi;Serge L. Beaucage;Jacqueline Conover.
Proceedings of the National Academy of Sciences of the United States of America (1996)

1930 Citations

Therapeutic potential of Toll-like receptor 9 activation

Arthur M. Krieg.
Nature Reviews Drug Discovery (2006)

1779 Citations

CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.

Rose S. Chu;Oleg S. Targoni;Arthur M. Krieg;Paul V. Lehmann.
Journal of Experimental Medicine (1997)

1267 Citations

Immunostimulatory nucleic acid molecules

Arthur M. Krieg;Joel N. Kline;Dennis Klinman;Alfred D. Steinberg.
(2004)

1226 Citations

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Marion Jurk;Florian Heil;Jörg Vollmer;Christian Schetter.
Nature Immunology (2002)

1160 Citations

Identification of CpG oligonucleotide sequences with high induction of IFN‐α/β in plasmacytoid dendritic cells

Anne Krug;Simon Rothenfusser;Veit Hornung;Bernd Jahrsdörfer.
European Journal of Immunology (2001)

1079 Citations

Induction of NK activity in murine and human cells by CpG motifs in oligodeoxynucleotides and bacterial DNA.

Z K Ballas;W L Rasmussen;A M Krieg.
Journal of Immunology (1996)

1027 Citations

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12.

Anne Krug;Andreas Towarowski;Stefanie Britsch;Simon Rothenfusser.
European Journal of Immunology (2001)

998 Citations

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