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Immunology

D-Index
67
Citations
16843
World Ranking
2662
National Ranking
1272

Overview

George J. Weiner is affiliated with the University of Iowa in the United States and has contributed extensively to the fields of medicine and immunology and microbiology. Their research primarily focuses on immunology, oncology, molecular biology, cancer research, and radiology, nuclear medicine, and imaging.

Their work covers a variety of topics including cancer immunotherapy and biomarkers, immunotherapy and immune responses, immune cell function and interaction, CAR-T cell therapy research, cancer genomics and diagnostics, immune response and inflammation, and monoclonal and polyclonal antibodies research.

George J. Weiner has authored multiple publications in leading scientific venues. Frequent publication venues for their work include:

  • Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Journal of Clinical Oncology
  • Journal for ImmunoTherapy of Cancer
  • Cancer Immunology Research

They have collaborated regularly with several co-authors, including:

  • Ahmad A. Tarhini
  • Caitlin D. Lemke
  • Martin D. McCarter
  • Igor Puzanov
  • Susanne M. Arnold

Notable recent publications include:

  • "Obesity diminishes response to PD-1-based immunotherapies in renal cancer," 2020, Journal for ImmunoTherapy of Cancer
  • "Insights from immuno-oncology: the Society for Immunotherapy of Cancer Statement on access to IL-6-targeting therapies for COVID-19," 2020, Journal for ImmunoTherapy of Cancer
  • "Prospective correlation between the patient microbiome with response to and development of immune-mediated adverse effects to immunotherapy in lung cancer," 2021, BMC Cancer
  • "Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization," 2020, The Journal of Immunology
  • "In situ immunization of a TLR9 agonist virus-like particle enhances anti-PD1 therapy," 2020, Journal for ImmunoTherapy of Cancer

The body of work established by George J. Weiner engages deeply with the mechanisms of immune response within oncology contexts. Their research spans both basic and clinical studies, emphasizing the interaction between immunotherapy agents and the body's immune function against cancer.

Best Publications

  • Rituximab: mechanism of action.

    George J. Weiner

  • CpG DNA: a potent signal for growth, activation, and maturation of human dendritic cells.

    G. Hartmann;G. J. Weiner;A. M. Krieg

  • Building better monoclonal antibody-based therapeutics.

    George J. Weiner

  • Immunostimulatory oligodeoxynucleotides containing the CpG motif are effective as immune adjuvants in tumor antigen immunization

    George J. Weiner;Hsin-Ming Liu;James E. Wooldridge;Christopher E. Dahle

  • Cancer immunotherapy comes of age.

    Suzanne L. Topalian;George J. Weiner;Drew M. Pardoll

  • Cancer and inflammation: Promise for biologic therapy

    Sandra Demaria;Eli Pikarsky;Michael Karin;Lisa M. Coussens

  • METHOD OF STIMULATING IMMUNOSYSTEM USING IMMUNOTHERAPEUTIC OLIGONUCLEOTIDE AND CYTOKINE, AND PRODUCT

    Krieg Arthur M;Weiner George

  • Randomized study of prophylactic platelet transfusion threshold during induction therapy for adult acute leukemia: 10,000/microL versus 20,000/microL.

    K D Heckman;G J Weiner;C S Davis;R G Strauss

  • Cancer Immunotherapy and Breaking Immune Tolerance: New Approaches to an Old Challenge

    Amani Makkouk;George J. Weiner

  • Divergent Therapeutic and Immunologic Effects of Oligodeoxynucleotides with Distinct CpG Motifs

    Zuhair K. Ballas;Arthur M. Krieg;Arthur M. Krieg;Arthur M. Krieg;Thomas Warren;Wendy Rasmussen;Wendy Rasmussen

  • Immunostimulatory oligodeoxynucleotides containing CpG motifs enhance the efficacy of monoclonal antibody therapy of lymphoma

    James E. Wooldridge;Zuhair Ballas;Arthur M. Krieg;George J. Weiner

  • Vitamin D Insufficiency and Prognosis in Non-Hodgkin's Lymphoma

    Matthew T. Drake;Matthew J. Maurer;Brian K. Link;Thomas M. Habermann

  • Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab

    Julie A. Bowles;Siao-Yi Wang;Brian K. Link;Barrett Allan

  • Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia

    Sonja I. Berndt;Christine F. Skibola;Christine F. Skibola;Vijai Joseph;Nicola J. Camp

  • Early event status informs subsequent outcome in newly diagnosed follicular lymphoma.

    Matthew J. Maurer;Emmanuel Bachy;Hervé Ghesquières;Stephen M. Ansell

  • NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement

    Siao Yi Wang;Emilian Racila;Ronald P. Taylor;George J. Weiner

  • Bispecific antibodies in cancer therapy.

    David M Segal;George J Weiner;Louis M Weiner

  • Uses of granulocyte-macrophage colony-stimulating factor in vaccine development.

    Thomas L. Warren;George J. Weiner

  • Granzyme B produced by human plasmacytoid dendritic cells suppresses T-cell expansion

    Bernd Jahrsdörfer;Angelika Vollmer;Sue E. Blackwell;Julia Maier

  • Oligodeoxynucleotide CpG 7909 delivered as intravenous infusion demonstrates immunologic modulation in patients with previously treated non-Hodgkin lymphoma.

    Brian K. Link;Zuhair K. Ballas;Daniel Weisdorf;James E. Wooldridge

Frequent Co-Authors

Thomas E. Witzig
Thomas E. Witzig Mayo Clinic
James R. Cerhan
James R. Cerhan Mayo Clinic
Susan L. Slager
Susan L. Slager Mayo Clinic
Arthur M. Krieg
Arthur M. Krieg University of Massachusetts Chan Medical School
Anne J. Novak
Anne J. Novak Mayo Clinic
Angela Brooks-Wilson
Angela Brooks-Wilson Simon Fraser University
David J. Inwards
David J. Inwards Mayo Clinic

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