D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 55 Citations 21,287 83 World Ranking 2661 National Ranking 1080

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • DNA
  • Enzyme

Molecular biology, TLR7, Immune system, Receptor and TLR8 are his primary areas of study. His Molecular biology research incorporates themes from Tumor necrosis factor alpha and Cytotoxic T cell. To a larger extent, Grayson B. Lipford studies Innate immune system with the aim of understanding TLR7.

Grayson B. Lipford has researched Immune system in several fields, including Adjuvant, In vitro and In vivo. His TLR8 research includes themes of Resiquimod and Virology. His studies deal with areas such as Dendritic cell and Cell biology as well as Toll-like receptor.

His most cited work include:

  • Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8 (3182 citations)
  • Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition (1331 citations)
  • Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848 (873 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Immune system, Molecular biology, Immunology, CpG site and Antigen. His Innate immune system and TLR7 investigations are all subjects of Immune system research. His Innate immune system study incorporates themes from Acquired immune system, Dendritic cell and CD14.

His Molecular biology study integrates concerns from other disciplines, such as Cytotoxic T cell, MHC class I, CD40, Oligonucleotide and Peptide. His Antigen study combines topics in areas such as Polynucleotide and Pharmacology. In general Receptor, his work in TLR8 is often linked to TLR9 linking many areas of study.

He most often published in these fields:

  • Immune system (29.27%)
  • Molecular biology (28.46%)
  • Immunology (21.95%)

What were the highlights of his more recent work (between 2008-2018)?

  • Nanocarriers (13.01%)
  • Immune system (29.27%)
  • Pharmacology (8.13%)

In recent papers he was focusing on the following fields of study:

Grayson B. Lipford mostly deals with Nanocarriers, Immune system, Pharmacology, Biochemistry and Antigen. His research in Immune system tackles topics such as Quinoline which are related to areas like Salt. His study in the field of Oligonucleotide, Antigen-presenting cell and Protein biosynthesis also crosses realms of Cellular transcription.

The various areas that Grayson B. Lipford examines in his Virology study include Conjugated system and Peptide. TLR7 and TLR8 are fields of study that intersect with his CpG Oligodeoxynucleotide research. Grayson B. Lipford integrates TLR7 with TLR9 in his research.

Between 2008 and 2018, his most popular works were:

  • Nanocarriers possessing components with different rates of release (55 citations)
  • Nanocarrier compositions with uncoupled adjuvant (46 citations)
  • Immunonanotherapeutics providing a th1-biased response (36 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • DNA
  • Enzyme

His main research concerns Nanocarriers, Biochemistry, Virology, Pharmacology and Antigen. His Nanocarriers investigation overlaps with other disciplines such as Adjuvant, Cancer research, Population, Nanotechnology and Engineering. Specifically, his work in Biochemistry is concerned with the study of Antigen-presenting cell.

His Virology study combines topics from a wide range of disciplines, such as Peptide and Microbiology. Grayson B. Lipford interconnects TLR7, Toll-like receptor, TLR8 and Immune system in the investigation of issues within Pharmacology. The study incorporates disciplines such as Receptor and Pyrimidine in addition to Antigen.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Species-Specific Recognition of Single-Stranded RNA via Toll-like Receptor 7 and 8

Florian Heil;Hiroaki Hemmi;Hubertus Hochrein;Franziska Ampenberger.
Science (2004)

4654 Citations

Human TLR9 confers responsiveness to bacterial DNA via species-specific CpG motif recognition

Stefan Bauer;Carsten J. Kirschning;Hans Häcker;Vanessa Redecke.
Proceedings of the National Academy of Sciences of the United States of America (2001)

1851 Citations

Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848

Marion Jurk;Florian Heil;Jörg Vollmer;Christian Schetter.
Nature Immunology (2002)

1235 Citations

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells

Tim Sparwasser;Eva Sophie Koch;Ramunas M. Vabulas;Klaus Heeg.
European Journal of Immunology (1998)

1017 Citations

CpG-DNA-specific activation of antigen-presenting cells requires stress kinase activity and is preceded by non-specific endocytosis and endosomal maturation.

Hans Häcker;Harald Mischak;Thomas Miethke;Susanne Liptay.
The EMBO Journal (1998)

868 Citations

CpG oligodeoxynucleotides trigger protective and curative Th1 responses in lethal murine leishmaniasis.

Stefan Zimmermann;Oliver Egeter;Susanne Hausmann;Grayson B. Lipford.
Journal of Immunology (1998)

727 Citations

The Toll-like receptor 7 (TLR7)-specific stimulus loxoribine uncovers a strong relationship within the TLR7, 8 and 9 subfamily.

Florian Heil;Parviz Ahmad-Nejad;Hiroaki Hemmi;Hubertus Hochrein.
European Journal of Immunology (2003)

708 Citations

Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner

Mark Rutz;Jochen Metzger;Tanja Gellert;Peter Luppa.
European Journal of Immunology (2004)

647 Citations

Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

Sander Zwaveling;Sandra C. Ferreira Mota;Jan Nouta;Mark Johnson.
Journal of Immunology (2002)

564 Citations

Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor-alpha-mediated shock.

Tim Sparwasser;Thomas Miethke;Grayson Lipford;Andreas Erdmann.
European Journal of Immunology (1997)

545 Citations

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