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Immunology

D-Index
80
Citations
21405
World Ranking
1642
National Ranking
65

Overview

Ferry Ossendorp is affiliated with Leiden University Medical Center in the Netherlands, contributing extensively to research in immunology and medicine. Their work predominantly focuses on fields such as Immunology and Microbiology, with significant involvement in subfields including Immunology, Oncology, Molecular Biology, Biomedical Engineering, and Pulmonary and Respiratory Medicine.

The research topics covered by Ossendorp span a diverse array of subjects related to immune system function and cancer treatment. Key areas include Immunotherapy and Immune Responses, Cancer Immunotherapy and Biomarkers, Nanoplatforms for cancer theranostics, CAR-T cell therapy research, vaccines and immunoinformatics approaches, Immune Cell Function and Interaction, and Photodynamic Therapy Research Studies.

Ossendorp's recent publications demonstrate a focus on cancer immunotherapy and drug delivery systems. Notable papers include:

  • Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy, 2020, Science Translational Medicine
  • Liposome-Based Drug Delivery Systems in Cancer Immunotherapy, 2020, Pharmaceutics
  • Current Challenges and Opportunities of Photodynamic Therapy against Cancer, 2023, Pharmaceutics
  • Preclinical and Clinical Evidence of Immune Responses Triggered in Oncologic Photodynamic Therapy: Clinical Recommendations, 2020, Journal of Clinical Medicine
  • Thermosensitive hydrogels as sustained drug delivery system for CTLA-4 checkpoint blocking antibodies, 2020, Journal of Controlled Release

Frequent collaborators in their research include Marcel Camps, Luis J. Cruz, Ramon Arens, Martine J. Jager, and Sen Ma. These coauthors have contributed to multiple projects, reflecting ongoing scientific partnerships.

Ossendorp's work appears regularly in prominent journals and publication venues such as Pharmaceutics, Journal of Controlled Release, Investigative Ophthalmology & Visual Science, ChemBioChem, and Methods in Molecular Biology. These venues illustrate the interdisciplinary nature of their research spanning immunology, drug delivery, and molecular science.

Best Publications

  • Therapeutic cancer vaccines

    Cornelis J.M. Melief;Thorbald van Hall;Ramon Arens;Ferry Ossendorp

  • Specific T Helper Cell Requirement for Optimal Induction of Cytotoxic T Lymphocytes against Major Histocompatibility Complex Class II Negative Tumors

    Ferry Ossendorp;Erica Mengedé;Marcel Camps;Rian Filius

  • Vaccines for established cancer: overcoming the challenges posed by immune evasion.

    Sjoerd H. van der Burg;Ramon Arens;Ferry Ossendorp;Thorbald van Hall

  • Decreased tumor surveillance in perforin-deficient mice.

    M. F. Van Den Broek;D. Kagi;F. Ossendorp;R. Toes

  • CD4 T cells and their role in antitumor immune responses.

    René E.M. Toes;Ferry Ossendorp;Rienk Offringa;Cornelis J.M. Melief

  • Proteasome and peptidase function in MHC-class-I-mediated antigen presentation.

    Peter Michael Kloetzel;Ferry Ossendorp

  • CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope

    Ania Skowera;Richard J. Ellis;Ruben Varela-Calviño;Sefina Arif

  • MHC II In dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways

    Sonja I. Buschow;Esther N. M. Nolte‐‘t Hoen;Guillaume Van Niel;Maaike S. Pols

  • Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.

    Maud Mayoux;Andreas Roller;Vesna Pulko;Stefano Sammicheli

  • Tumor-draining lymph nodes are pivotal in PD-1/PD-L1 checkpoint therapy.

    Marieke F. Fransen;Mark Schoonderwoerd;Philipp Knopf;Marcel G.M. Camps

  • Efficient Identification of Novel HLA-A * 0201-presented Cytotoxic T Lymphocyte Epitopes in the Widely Expressed Tumor Antigen PRAME by Proteasome-mediated Digestion Analysis

    Jan H. Kessler;Nico J. Beekman;Sandra A. Bres-Vloemans;Pauline Verdijk

  • Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

    Monique Kleijmeer;Georg Ramm;Danita Schuurhuis;Janice Griffith

  • Autoreactive CD8 T cells associated with β cell destruction in type 1 diabetes

    Gabrielle G. M. Pinkse;Odette H. M. Tysma;Cees A. M. Bergen;Michel G. D. Kester

  • Antigen-Antibody Immune Complexes Empower Dendritic Cells to Efficiently Prime Specific CD8+ CTL Responses In Vivo

    Danita H. Schuurhuis;Andreea Ioan-Facsinay;Bas Nagelkerken;Jolien J. van Schip

  • Expression of the serpin serine protease inhibitor 6 protects dendritic cells from cytotoxic T lymphocyte-induced apoptosis: differential modulation by T helper type 1 and type 2 cells.

    Jan Paul Medema;Danita H. Schuurhuis;Delphine Rea;Joost van Tongeren

  • CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses.

    Rodney A. Rosalia;Luis J. Cruz;Suzanne van Duikeren;Angelino T. Tromp

  • Immature Dendritic Cells Acquire Cd8+Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli

    Danita H. Schuurhuis;Sandra Laban;René E.M. Toes;Paola Ricciardi-Castagnoli

  • PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity.

    A. L. Silva;P. C. Soema;B. Slütter;F. Ossendorp

  • Strategies for immunotherapy of cancer

    C J Melief;R E Toes;J P Medema;S H van der Burg

  • Dendritic cells process synthetic long peptides better than whole protein, improving antigen presentation and T-cell activation.

    Rodney A. Rosalia;Esther D. Quakkelaar;Anke Redeker;Selina Khan

  • Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination.

    Guillaume van Niel;Richard Wubbolts;Toine ten Broeke;Sonja I. Buschow

Frequent Co-Authors

Cornelis J. M. Melief
Cornelis J. M. Melief ISA Pharmaceuticals (Netherlands)
Jan W. Drijfhout
Jan W. Drijfhout Leiden University Medical Center
Thorbald van Hall
Thorbald van Hall Leiden University Medical Center
Sjoerd H. van der Burg
Sjoerd H. van der Burg Leiden University Medical Center
Ramon Arens
Ramon Arens Leiden University Medical Center
Rienk Offringa
Rienk Offringa German Cancer Research Center
Herman S. Overkleeft
Herman S. Overkleeft Leiden University
René E. M. Toes
René E. M. Toes Leiden University Medical Center
J. Sjef Verbeek
J. Sjef Verbeek Leiden University Medical Center
Wim Jiskoot
Wim Jiskoot Leiden University

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