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Neuroscience

D-Index
61
Citations
15174
World Ranking
3649
National Ranking
1679

Overview

Gregory J. Brewer is affiliated with the University of California, Irvine in the United States. Their research contributions span neuroscience and medicine, with particular emphasis on cognitive and cellular neuroscience, physiology, epidemiology, and biological psychiatry.

The scientist's work covers multiple topics including neural dynamics and brain function, neuroscience and neural engineering, autophagy in disease and therapy, Alzheimer's disease research and treatments, neuroscience and neuropharmacology research, tryptophan and brain disorders, and advanced memory and neural computing.

Frequent publication venues for Brewer include:

  • GeroScience
  • Frontiers in Neural Circuits
  • Zenodo (CERN European Organization for Nuclear Research)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Alzheimer s Disease

They often collaborate with several researchers, including:

  • William C. Tang
  • Yash S. Vakilna
  • Ricardo A. Santana-Martínez
  • Bruce C. Wheeler
  • Joshua McWhirt

Notable recent papers authored or co-authored by Gregory J. Brewer include:

  • "GTP energy dependence of endocytosis and autophagy in the aging brain and Alzheimer's disease," 2023, published in GeroScience
  • "The Flow of Axonal Information Among Hippocampal Subregions: 1. Feed-Forward and Feedback Network Spatial Dynamics Underpinning Emergent Information Processing," 2021, published in Frontiers in Neural Circuits
  • "Age-Related Oxidative Redox and Metabolic Changes Precede Intraneuronal Amyloid-β Accumulation and Plaque Deposition in a Transgenic Alzheimer's Disease Mouse Model," 2022, published in Journal of Alzheimer s Disease
  • "Hippocampal network axons respond to patterned theta burst stimulation with lower activity of initially higher spike train similarity from EC to DG and later similarity of axons from CA1 to EC," 2023, published in Journal of Neural Engineering
  • "Pharmacokinetic and pharmacodynamic assessment of oral nicotinamide in the NEAT clinical trial for early Alzheimer's disease," 2025, published in Alzheimer s Research & Therapy

Best Publications

  • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination

    G. J. Brewer;J. R. Torricelli;E. K. Evege;P. J. Price

  • Serum-free B27/neurobasal medium supports differentiated growth of neurons from the striatum, substantia nigra, septum, cerebral cortex, cerebellum, and dentate gyrus

    G. J. Brewer

  • Isolation and culture of adult rat hippocampal neurons

    Gregory J Brewer

  • Isolation and culture of adult neurons and neurospheres

    Gregory J Brewer;John R Torricelli

  • Survival and growth of hippocampal neurons in defined medium at low density: advantages of a sandwich culture technique or low oxygen

    Gregory J. Brewer;Carl W. Cotman

  • Protective Effect of the Energy Precursor Creatine Against Toxicity of Glutamate and β-Amyloid in Rat Hippocampal Neurons

    Gregory J. Brewer;Theo W. Wallimann

  • Amyloid-β as a modulator of synaptic plasticity.

    Mordhwaj S. Parihar;Gregory J. Brewer

  • NMDA receptor regulation of neuronal morphology in cultured hippocampal neurons.

    G.J. Brewer;C.W. Cotman

  • Long-term stability of grafted polyethylene glycol surfaces for use with microstamped substrates in neuronal cell culture.

    Darren W. Branch;Bruce C. Wheeler;Gregory J. Brewer;Deborah E. Leckband

  • Increased regional brain concentrations of ceruloplasmin in neurodegenerative disorders.

    D.A. Loeffler;P.A. LeWitt;P.L. Juneau;A.A.F. Sima

  • Microcontact printing for precise control of nerve cell growth in culture.

    B. C. Wheeler;J. M. Corey;G. J. Brewer;D. W. Branch

  • Compliance of hippocampal neurons to patterned substrate networks

    J. M. Corey;B. C. Wheeler;G. J. Brewer

  • Long-term maintenance of patterns of hippocampal pyramidal cells on substrates of polyethylene glycol and microstamped polylysine

    D.W. Branch;B.C. Wheeler;G.J. Brewer;D.E. Leckband

  • Microstamp patterns of biomolecules for high-resolution neuronal networks

    D. W. Branch;J. M. Corey;J. A. Weyhenmeyer;G. J. Brewer

  • Modulation of neural network activity by patterning.

    John C. Chang;Gregory J. Brewer;Bruce C. Wheeler

  • Apolipoprotein E4 inhibits, and apolipoprotein E3 promotes neurite outgrowth in cultured adult mouse cortical neurons through the low-density lipoprotein receptor-related protein.

    Britto P. Nathan;Yanwen Jiang;Gene K. Wong;Fei Shen

  • Mitoenergetic failure in Alzheimer disease.

    Mordhwaj S Parihar;Gregory J. Brewer

  • A modified microstamping technique enhances polylysine transfer and neuronal cell patterning.

    John C. Chang;Gregory J. Brewer;Bruce C. Wheeler

  • Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture.

    Gregory J. Brewer

  • Designing Neural Networks in Culture

    B.C. Wheeler;G.J. Brewer

Frequent Co-Authors

Carl W. Cotman
Carl W. Cotman University of California, Irvine
Robert G. Struble
Robert G. Struble Southern Illinois University School of Medicine
James A. Joseph
James A. Joseph Tufts University
Andreas Offenhäusser
Andreas Offenhäusser Forschungszentrum Jülich
Rachael L. Neve
Rachael L. Neve Harvard University
Stephen P. DeWeerth
Stephen P. DeWeerth Lehigh University
Xiao-Xin Yan
Xiao-Xin Yan Central South University
Roberta Diaz Brinton
Roberta Diaz Brinton University of Arizona
Mark G. Allen
Mark G. Allen University of Pennsylvania
Wolfgang Knoll
Wolfgang Knoll Austrian Institute of Technology

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