World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
26021
World Ranking
2246
National Ranking
1206

Research.com Recognitions

  • 2010 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

G. Stanley McKnight is affiliated with the University of Washington in the United States. Their research spans multiple fields including biochemistry, genetics and molecular biology, medicine, and neuroscience. Within these broad areas, they focus on molecular biology, cell biology, sensory systems, endocrinology, diabetes and metabolism, and reproductive medicine.

The scientist's recent publications address a variety of topics related to cellular and molecular processes alongside neuroendocrinology. Notable papers include "Molecular and anatomical characterization of parabrachial neurons and their axonal projections" (2022, eLife), "Mislocalization of protein kinase A drives pathology in Cushing's syndrome" (2022, Cell Reports), and an earlier version of the first paper published in 2022 in bioRxiv (Cold Spring Harbor Laboratory). Other publications include work on the activation of hypothalamic neurons influencing testosterone synthesis in adult male mice (2020, bioRxiv) and investigation into protein kinase A mislocalization related to Cushing's syndrome (2022, SSRN Electronic Journal).

Areas of study in which McKnight has contributed include:

  • Single-cell and spatial transcriptomics
  • Olfactory and sensory function studies
  • Hippo pathway signaling and YAP/TAZ
  • Pituitary gland disorders and treatments
  • Biochemical analysis and sensing techniques
  • Cellular mechanics and interactions
  • Neuroinflammation and neurodegeneration mechanisms

Frequent coauthors collaborating with McKnight include Elisenda Sanz, Richard D. Palmiter, Mitchell H. Omar, Dominic P. Byrne, and Kiana N. Jones.

McKnight's work has been published across various venues, with repeated contributions to bioRxiv (Cold Spring Harbor Laboratory), as well as publications in eLife, Cell Reports, SSRN Electronic Journal, and UNC Libraries.

McKnight's research encompasses both fundamental molecular pathways and clinical implications, particularly in relation to endocrine disorders and neuronal function. The diversity of topics covered reflects a multidisciplinary approach integrating molecular techniques with physiological contexts.

In 2010, G. Stanley McKnight was recognized as a Fellow of the American Association for the Advancement of Science (AAAS), marking a professional milestone.

Best Publications

  • Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy

    Frank H Yu;Massimo Mantegazza;Ruth E Westenbroek;Carol A Robbins

  • Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

    G S McKnight;R D Palmiter

  • Cell-type-specific isolation of ribosome-associated mRNA from complex tissues

    Elisenda Sanz;Linghai Yang;Thomas Su;David R. Morris

  • Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression.

    R. P. Matthews;C. R. Guthrie;L. M. Wailes;Xinyu Zhao

  • Genetically lean mice result from targeted disruption of the RIIβ subunit of protein kinase A

    David E. Cummings;Eugene P. Brandon;Josep V. Planas;Kouros Motamed

  • Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice.

    Susan E. Hamilton;Michael D. Loose;Ming Qi;Allan I. Levey

  • Psychosis pathways converge via D2high dopamine receptors.

    Philip Seeman;Johannes Schwarz;Jiang Fan Chen;Henry Szechtman

  • A genetic test of the effects of mutations in PKA on mossy fiber ltp and its relation to spatial and contextual learning

    Yan You Huang;Eric R. Kandel;Lauren Varshavsky;Eugene P. Brandont

  • Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity.

    Srikanth Nagalla;Chad Shaw;Chad Shaw;Xianguo Kong;Altaf A. Kondkar

  • Distinct patterns of cAMP-dependent protein kinase gene expression in mouse brain.

    Gary Cadd;G. Stanley McKnight

  • Sperm-specific protein kinase A catalytic subunit Cα2 orchestrates cAMP signaling for male fertility

    Michael A. Nolan;Donner F. Babcock;Gunther Wennemuth;William Brown

  • Regulation of transcription by cyclic AMP-dependent protein kinase.

    P L Mellon;C H Clegg;L A Correll;G S McKnight

  • Diminished Inflammation and Nociceptive Pain with Preservation of Neuropathic Pain in Mice with a Targeted Mutation of the Type I Regulatory Subunit of cAMP-Dependent Protein Kinase

    Annika B. Malmberg;Eugene P. Brandon;Rejean L. Idzerda;Hantao Liu

  • Compensatory Regulation of RIα Protein Levels in Protein Kinase A Mutant Mice

    Paul S. Amieux;David E. Cummings;Kouros Motamed;Eugene P. Brandon

  • Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4.

    J. Y. Wu;T. J. Ribar;D. E. Cummings;K. A. Burton

  • Hippocampal Long-Term Depression and Depotentiation Are Defective in Mice Carrying a Targeted Disruption of the Gene Encoding the RI Beta Subunit of cAMP-dependent Protein Kinase

    E. P. Brandon;Min Zhuo;Yan-You Huang;Ming Qi

  • The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.

    J D Scott;M B Glaccum;M J Zoller;M D Uhler

  • PKA isoforms, neural pathways, and behaviour: making the connection

    Eugene P Brandon;Rejean L Idzerda;G Stanley McKnight

  • Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1 beta action.

    B T Gjertsen;G Mellgren;A Otten;E Maronde

  • The induction of ovalbumin and conalbumin mRNA by estrogen and progesterone in chick oviduct explant cultures

    G. Stanley McKnight

Frequent Co-Authors

Johannes W. Hell
Johannes W. Hell University of California, Davis
John D. Scott
John D. Scott University of Washington
David E. Cummings
David E. Cummings University of Washington
Richard D. Palmiter
Richard D. Palmiter University of Washington
Ruth E. Westenbroek
Ruth E. Westenbroek University of Washington
Colleen M. Niswender
Colleen M. Niswender Vanderbilt University
Luis F. Santana
Luis F. Santana University of California, Davis
Chad A. Shaw
Chad A. Shaw Baylor College of Medicine
Suzanne M. Leal
Suzanne M. Leal Columbia University Medical Center
Evan E. Eichler
Evan E. Eichler University of Washington

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