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Genetics

D-Index
89
Citations
33968
World Ranking
1110
National Ranking
533

Research.com Recognitions

  • 2013 - Member of the National Academy of Sciences
  • 2010 - Fellow of the American Academy of Arts and Sciences
  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Fred Winston is affiliated with Harvard University in the United States and specializes in the field of Biochemistry, Genetics and Molecular Biology, with a focus on Molecular Biology and Pharmacology as subfields. Their research primarily covers topics related to Genomics and Chromatin Dynamics, RNA and protein synthesis mechanisms, RNA Research and Splicing, DNA Repair Mechanisms, RNA modifications and cancer, Microbial Natural Products and Biosynthesis, and Fungal and yeast genetics research.

Recent publications by Fred Winston include:

  • The role of FACT in managing chromatin: disruption, assembly, or repair? (2020, Nucleic Acids Research)
  • The biochemical and genetic discovery of the SAGA complex (2020, Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms)
  • Essential histone chaperones collaborate to regulate transcription and chromatin integrity (2021, Genes & Development)
  • The conserved elongation factor Spn1 is required for normal transcription, histone modifications, and splicing in Saccharomyces cerevisiae (2020, Nucleic Acids Research)
  • Insights into Spt6: a histone chaperone that functions in transcription, DNA replication, and genome stability (2023, Trends in Genetics)

Frequent coauthors associated with Fred Winston include James Chuang, Dhawal Jain, Natalia I. Reim, Peter J. Park, and Francheska López-Rivera.

Typical publication venues for Fred Winston's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nucleic Acids Research
  • Trends in Genetics
  • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
  • Genes & Development

Fred Winston has been recognized with multiple professional honors, including being named Member of the National Academy of Sciences in 2013, Fellow of the American Academy of Arts and Sciences in 2010, and Fellow of the American Association for the Advancement of Science (AAAS) in 2003.

Best Publications

  • Methods in Yeast Genetics: A Laboratory Course Manual

    Mark D. Rose;Fred Winston;Philip Hieter

  • A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformation of Escherichia coli.

    Charles S. Hoffman;Fred Winston

  • Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: characterization of an Ada complex and the SAGA (Spt/Ada) complex.

    P A Grant;L Duggan;J Côté;S M Roberts

  • Construction of a set of convenient Saccharomyces cerevisiae strains that are isogenic to S288C.

    Fred Winston;Catherine Dollard;Stephanie L. Ricupero-Hovasse

  • DSIF, A NOVEL TRANSCRIPTION ELONGATION FACTOR THAT REGULATES RNA POLYMERASE II PROCESSIVITY, IS COMPOSED OF HUMAN SPT4 AND SPT5 HOMOLOGS

    Tadashi Wada;Toshiyuki Takagi;Yuki Yamaguchi;Anwarul Ferdous

  • Yeast SNF/SWI transcriptional activators and the SPT/SIN chromatin connection.

    Fred Winston;Marian Carlson

  • Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae

    Scott D. Briggs;Mary Bryk;Brian D. Strahl;Wang L. Cheung

  • Intergenic transcription is required to repress the Saccharomyces cerevisiae SER3 gene

    Joseph A. Martens;Lisa Laprade;Fred Winston

  • Evidence that SNF2/SWI2 and SNF5 activate transcription in yeast by altering chromatin structure.

    Joel N. Hirschhorn;Steven A. Brown;Chris D. Clark;Fred Winston

  • Transcription Elongation Factors Repress Transcription Initiation from Cryptic Sites

    Craig D. Kaplan;Lisa Laprade;Fred Winston

  • Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.

    Grant A. Hartzog;Tadashi Wada;Hiroshi Handa;Fred Winston

  • Whole-genome expression analysis of snf/swi mutants of Saccharomyces cerevisiae.

    Priya Sudarsanam;Vishwanath R. Iyer;Patrick O. Brown;Fred Winston

  • The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins

    Susan R. Haynes;Catherine Dollard;Fred Winston;Stephan Beck

  • The Swi/Snf family nucleosome-remodeling complexes and transcriptional control.

    Priya Sudarsanam;Fred Winston

  • Recent advances in understanding chromatin remodeling by Swi/Snf complexes.

    Joseph A Martens;Fred Winston

  • Redundant roles for the TFIID and SAGA complexes in global transcription

    Tong Ihn Lee;Helen C. Causton;Frank C. P. Holstege;Frank C. P. Holstege;Wu-Cheng Shen

  • Evidence That Spt6p Controls Chromatin Structure by a Direct Interaction with Histones

    Alex Bortvin;Fred Winston

  • Functional Organization of the Yeast SAGA Complex: Distinct Components Involved in Structural Integrity, Nucleosome Acetylation, and TATA-Binding Protein Interaction

    David E. Sterner;Patrick A. Grant;Shannon M. Roberts;Laura J. Duggan

  • Mutations affecting Ty-mediated expression of the HIS4 gene of Saccharomyces cerevisiae.

    Fred Winston;Deborah T. Chaleff;Barbara Valent;Gerald R. Fink

  • The bromodomain: a chromatin-targeting module?

    F Winston;C D Allis

Frequent Co-Authors

Peter J. Park
Peter J. Park Harvard University
Bradley R. Cairns
Bradley R. Cairns University of Utah
Jürg Bähler
Jürg Bähler University College London
David Botstein
David Botstein Princeton University
Judit Villén
Judit Villén University of Washington
Joel N. Hirschhorn
Joel N. Hirschhorn Boston Children's Hospital
Shelley L. Berger
Shelley L. Berger University of Pennsylvania
Frank C. P. Holstege
Frank C. P. Holstege Utrecht University
Steven P. Gygi
Steven P. Gygi Harvard University

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