His primary areas of investigation include Genetics, Molecular biology, Cell biology, Proteomics and Histone methyltransferase. Michael P. Washburn interconnects G2-M DNA damage checkpoint, Cyclin A2, Histone acetyltransferase, Cyclin A and Cyclin D in the investigation of issues within Molecular biology. The various areas that Michael P. Washburn examines in his Cell biology study include Ubiquitin, Spindle pole body, Saccharomyces cerevisiae and Cell growth.
His work deals with themes such as Proteome, Bottom-up proteomics, Computational biology and Functional genomics, which intersect with Proteomics. His studies deal with areas such as Mass spectrometry and Shotgun proteomics as well as Computational biology. His work focuses on many connections between Histone methyltransferase and other disciplines, such as Histone H2A, that overlap with his field of interest in Histone octamer.
The scientist’s investigation covers issues in Cell biology, Genetics, Computational biology, Histone and Proteomics. His research integrates issues of Protein subunit, Ubiquitin ligase, Transcription factor, Molecular biology and Transcription in his study of Cell biology. His Molecular biology research is multidisciplinary, incorporating perspectives in Histone acetyltransferase, RNA polymerase II, Signal transduction and Histone H2A.
His Computational biology study combines topics in areas such as Protein–protein interaction, Quantitative proteomics, HEK 293 cells, Interactome and Acetyltransferase. His studies in Histone integrate themes in fields like Chromatin, Regulation of gene expression and Acetylation. His Proteomics research incorporates themes from Proteome, Bioinformatics and Mass spectrometry.
His main research concerns Cell biology, Computational biology, Histone, Chromatin and Proteomics. His research in Cell biology intersects with topics in Ubiquitin ligase and Transformation. The Computational biology study combines topics in areas such as Acetyltransferase, Proteome, Interaction network and Protein–protein interaction.
His biological study spans a wide range of topics, including Acetylation, Protein subunit, Yeast, Function and Mediator. Many of his research projects under Proteomics are closely connected to Topology with Topology, tying the diverse disciplines of science together. He combines subjects such as Chromatography and Orbitrap with his study of Quantitative proteomics.
His scientific interests lie mostly in Cell biology, Protein subunit, Histone, Kinase and Transcription factor. His Cell biology study combines topics from a wide range of disciplines, such as Gene expression, SPOP, Ubiquitin ligase and Systemic inflammation. As part of one scientific family, he deals mainly with the area of Protein subunit, narrowing it down to issues related to the SAGA complex, and often WAVE regulatory complex, Actin, Actin cytoskeleton and Nucleosome.
His Histone research includes themes of Biophysics, DSIF, Cajal body, Small nuclear RNA and Mediator. Michael P. Washburn has researched Kinase in several fields, including Cytoplasm, Nuclear localization sequence, Nucleus, Wild type and Nuclear transport. His Transcription factor research is multidisciplinary, incorporating elements of Cancer research, Ubiquitin and Cereblon.
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Large-scale analysis of the yeast proteome by multidimensional protein identification technology.
Michael P. Washburn;Dirk Wolters;John R. Yates;John R. Yates.
Nature Biotechnology (2001)
An Automated Multidimensional Protein Identification Technology for Shotgun Proteomics
Dirk A. Wolters;Michael P. Washburn;John R. Yates.
Analytical Chemistry (2001)
A proteomic view of the Plasmodium falciparum life cycle
Laurence Florens;Michael P. Washburn;J. Dale Raine;Robert M. Anthony.
Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription.
Michael J. Carrozza;Bing Li;Laurence Florens;Tamaki Suganuma.
Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein
Kasia Hrecka;Caili Hao;Magda Gierszewska;Selene K. Swanson.
The CRAPome: a contaminant repository for affinity purification–mass spectrometry data
Dattatreya Mellacheruvu;Zachary Wright;Amber L. Couzens;Jean Philippe Lambert.
Nature Methods (2013)
Statistical Analysis of Membrane Proteome Expression Changes in Saccharomyces cerevisiae
Boris Zybailov;Amber L. Mosley;Mihaela E. Sardiu;Michael K. Coleman.
Journal of Proteome Research (2006)
Acetylation by Tip60 Is Required for Selective Histone Variant Exchange at DNA Lesions
Thomas Kusch;Laurence Florens;W. Hayes MacDonald;Selene K. Swanson.
Shotgun identification of protein modifications from protein complexes and lens tissue
Michael J. MacCoss;W. Hayes McDonald;Anita Saraf;Rovshan Sadygov.
Proceedings of the National Academy of Sciences of the United States of America (2002)
Analysis of quantitative proteomic data generated via multidimensional protein identification technology.
Michael P. Washburn;Ryan Ulaszek;Cosmin Deciu;and David M. Schieltz.
Analytical Chemistry (2002)
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