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Chemistry

D-Index
57
Citations
10296
World Ranking
11217
National Ranking
3056

Overview

Rangaramanujam M. Kannan is affiliated with Johns Hopkins University School of Medicine in the United States. Their research spans multiple fields, including Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience, with a particular focus on molecular biology and neurology within these domains.

The scientist's work prominently addresses topics such as neuroinflammation and neurodegeneration mechanisms, RNA interference and gene delivery, and dendrimers and hyperbranched polymers. Additional research interests include retinal diseases and treatments, immune cells in cancer, advanced biosensing and bioanalysis techniques, as well as Alzheimer's disease research and treatments.

Among their recent publications are:

  • Dendrimer mediated targeted delivery of sinomenine for the treatment of acute neuroinflammation in traumatic brain injury, 2020, Journal of Controlled Release
  • Glycosylation of PAMAM dendrimers significantly improves tumor macrophage targeting and specificity in glioblastoma, 2021, Journal of Controlled Release
  • Dense hydroxyl polyethylene glycol dendrimer targets activated glia in multiple CNS disorders, 2020, Science Advances
  • Dendrimer size effects on the selective brain tumor targeting in orthotopic tumor models upon systemic administration, 2020, Bioengineering & Translational Medicine
  • Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity, 2022, Autophagy

Frequent co-authors in their body of work include Sujatha Kannan, Anjali Sharma, Rishi Sharma, Wathsala Liyanage, and Siva P. Kambhampati.

The researcher has published extensively in several scientific venues, notably the Journal of Controlled Release, Bioengineering & Translational Medicine, Biomacromolecules, bioRxiv (Cold Spring Harbor Laboratory), and Pharmaceutics.

Best Publications

  • Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications

    Anupa R. Menjoge;Rangaramanujam M. Kannan;Rangaramanujam M. Kannan;Donald A. Tomalia

  • Drug complexation, in vitro release and cellular entry of dendrimers and hyperbranched polymers

    Parag Kolhe;Ekta Misra;Rangaramanujam M. Kannan;Sujatha Kannan

  • The effect of surface functionality on cellular trafficking of dendrimers.

    Omathanu P. Perumal;Rajyalakshmi Inapagolla;Sujatha Kannan;Rangaramanujam M. Kannan

  • Improvement in ductility of chitosan through blending and copolymerization with PEG: FTIR investigation of molecular interactions

    Parag Kolhe;Rangaramanujam M. Kannan

  • Poly(amidoamine) dendrimer-drug conjugates with disulfide linkages for intracellular drug delivery.

    Yunus E. Kurtoglu;Raghavendra S. Navath;Raghavendra S. Navath;Bing Wang;Bing Wang;Sujatha Kannan;Sujatha Kannan

  • Preparation, cellular transport, and activity of polyamidoamine-based dendritic nanodevices with a high drug payload.

    Parag Kolhe;Jayant Khandare;Omathanu Pillai;Sujatha Kannan

  • Activity of dendrimer-methotrexate conjugates on methotrexate-sensitive and -resistant cell lines.

    Sezen Gurdag;Jayant Khandare;Sarah Stapels;Larry H. Matherly

  • Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration.

    Raymond Iezzi;Raymond Iezzi;Bharath R. Guru;Inna V. Glybina;Manoj K. Mishra

  • Dendrimer−Drug Conjugates for Tailored Intracellular Drug Release Based on Glutathione Levels

    Raghavendra S. Navath;Yunus E. Kurtoglu;Bing Wang;Sujatha Kannan

  • Synthesis, Cellular Transport, and Activity of Polyamidoamine Dendrimer−Methylprednisolone Conjugates

    Jayant Khandare;Parag Kolhe;Omathanu Pillai;Sujatha Kannan

  • Drug release characteristics of PAMAM dendrimer-drug conjugates with different linkers.

    Yunus E. Kurtoglu;Manoj K. Mishra;Sujatha Kannan;Sujatha Kannan;Rangaramanujam M. Kannan;Rangaramanujam M. Kannan

  • Dendrimer Brain Uptake and Targeted Therapy for Brain Injury in a Large Animal Model of Hypothermic Circulatory Arrest

    Manoj K. Mishra;Claude A. Beaty;Wojciech G. Lesniak;Siva P. Kambhampati

  • Subconjunctival injectable dendrimer-dexamethasone gel for the treatment of corneal inflammation

    Uri Soiberman;Siva P. Kambhampati;Tony Wu;Manoj K. Mishra

  • Targeting Mitochondrial Dysfunction and Oxidative Stress in Activated Microglia using Dendrimer-Based Therapeutics.

    Anjali Sharma;Kevin Liaw;Kevin Liaw;Rishi Sharma;Zhi Zhang

  • Dynamics of cellular entry and drug delivery by dendritic polymers into human lung epithelial carcinoma cells

    Sujatha Kannan;Parag Kolhe;Vania Raykova;Maria Glibatec

  • Dendrimer Nanoparticles for Ocular Drug Delivery

    Siva P. Kambhampati;Rangaramanujam M. Kannan

  • Transfer of PAMAM dendrimers across human placenta: prospects of its use as drug carrier during pregnancy.

    Anupa R. Menjoge;Amber L. Rinderknecht;Raghavendra S. Navath;Raghavendra S. Navath;Masoud Faridnia

  • Nanoscale effects in dendrimer-mediated targeting of neuroinflammation.

    Elizabeth Nance;Fan Zhang;Manoj K. Mishra;Zhi Zhang

  • Supercritical CO2 dispersion of nano-clays and clay/polymer nanocomposites

    Steven Horsch;Gulay Serhatkulu;Esin Gulari;Rangaramanujam M. Kannan

  • Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation and in vitro and in vivo evaluation.

    Raghavendra S. Navath;Anupa R. Menjoge;Anupa R. Menjoge;Hui Dai;Hui Dai;Roberto Romero

  • Evolution of Microstructure and Viscoelasticity during Flow Alignment of a Lamellar Diblock Copolymer

    Rangaramanujam M. Kannan;Julia A. Kornfield

Frequent Co-Authors

Julia A. Kornfield
Julia A. Kornfield California Institute of Technology
Mary E. Blue
Mary E. Blue Kennedy Krieger Institute
Gerard A. Lutty
Gerard A. Lutty Johns Hopkins University School of Medicine
Justin Hanes
Justin Hanes Johns Hopkins University
Barbara S. Slusher
Barbara S. Slusher Johns Hopkins University School of Medicine
Donald A. Tomalia
Donald A. Tomalia Michigan State University
Stephanie L. Brock
Stephanie L. Brock Wayne State University
Mikhail V. Pletnikov
Mikhail V. Pletnikov Johns Hopkins University
Mohd. Shkir
Mohd. Shkir King Khalid University
Paul A. Watkins
Paul A. Watkins Kennedy Krieger Institute

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