The scientist’s investigation covers issues in Stem cell, Progenitor cell, Pathology, Molecular biology and Hepatitis B virus. His Stem cell study integrates concerns from other disciplines, such as Embryonic stem cell, Cancer research, Cellular differentiation and Amniotic epithelial cells. His study in Embryonic stem cell is interdisciplinary in nature, drawing from both Endocrinology and Internal medicine.
His Progenitor cell research includes themes of Haematopoiesis and Transplantation. His Hepatitis B virus study is associated with Virology. His HBsAg study combines topics in areas such as Liver disease and Hepatitis.
David A. Shafritz spends much of his time researching Molecular biology, Virology, Hepatitis B virus, Progenitor cell and Internal medicine. His Molecular biology study incorporates themes from Gene expression, Cellular differentiation, RNA, Complementary DNA and Messenger RNA. His work deals with themes such as Antibody and DNA, which intersect with Virology.
His Hepatitis B virus study combines topics from a wide range of disciplines, such as Liver disease, Hepatitis B and Hepatitis. The study incorporates disciplines such as Haematopoiesis, Liver regeneration, Transplantation and Pathology in addition to Progenitor cell. His research in Internal medicine intersects with topics in Gastroenterology, Endocrinology and Cell growth.
His primary areas of investigation include Progenitor cell, Stem cell, Pathology, Cancer research and Internal medicine. He has researched Progenitor cell in several fields, including Molecular biology, Immunology, Transplantation and Hepatic stellate cell. His Molecular biology research includes elements of Complementary DNA and Liver injury.
The HBeAg, Hepatitis, HBsAg and Hepatitis B virus research he does as part of his general Immunology study is frequently linked to other disciplines of science, such as Liver cytology, therefore creating a link between diverse domains of science. His Stem cell research is multidisciplinary, incorporating perspectives in Embryonic stem cell, Somatic cell, Cellular differentiation and Liver regeneration. Internal medicine is frequently linked to Endocrinology in his study.
His scientific interests lie mostly in Stem cell, Progenitor cell, Immunology, Liver cytology and Haematopoiesis. His studies deal with areas such as Embryonic stem cell, Cancer research and Liver regeneration as well as Stem cell. His work carried out in the field of Progenitor cell brings together such families of science as Transplantation and Pathology.
Immunology is often connected to Virology in his work. His Haematopoiesis research focuses on CD34 and how it connects with Hematopoietic stem cell, Hepatocyte growth factor, Homing and Stem cell factor. His studies in Cell biology integrate themes in fields like Internal medicine and Endocrinology.
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Integration of hepatitis B virus DNA into the genome of liver cells in chronic liver disease and hepatocellular carcinoma. Studies in percutaneous liver biopsies and post-mortem tissue specimens.
David A. Shafritz;Daniel Shouval;Howard I. Sherman;Stefanos J. Hadziyannis.
The New England Journal of Medicine (1981)
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver.
Orit Kollet;Shoham Shivtiel;Yuan Qing Chen;Jenny Suriawinata.
Journal of Clinical Investigation (2003)
Long-Term, Near-Total Liver Replacement by Transplantation of Isolated Hepatocytes in Rats Treated with Retrorsine
Ezio Laconi;Ran Oren;Deb K. Mukhopadhyay;Ethel Hurston.
American Journal of Pathology (1998)
Analysis of Liver Disease, Nuclear HBcAg, Viral Replication, and Hepatitis B Virus DNA in Liver and Serum of HBcAg Vs. Anti‐HBe Positive Carriers of Hepatitis B Virus
Stephanos J. Hadziyannis;Harvey M. Lieberman;Gerassimos G. Karvountzis;David A. Shafritz.
BMP-4 is required for hepatic specification of mouse embryonic stem cell–derived definitive endoderm
Valerie Gouon-Evans;Lise Boussemart;Paul Gadue;Dirk Nierhoff;Dirk Nierhoff.
Nature Biotechnology (2006)
Identification of integrated hepatitis B virus DNA and expression of viral RNA in an HBsAg-producing human hepatocellular carcinoma cell line
Prasanta R. Chakraborty;Nelson Ruiz-Opazo;Daniel Shouval;David A. Shafritz.
Detection of hepatitis B virus DNA directly in human serum by a simplified molecular hybridization test: comparison to HBeAg/anti-HBe status in HBsAg carriers.
Harvey M. Lieberman;Douglas R. Labrecque;Michael C. Kew;Stefanos J. Hadziyannis.
Proliferation and differentiation of fetal liver epithelial progenitor cells after transplantation into adult rat liver.
Mariana D. Dabeva;Petko M. Petkov;Jaswinder Sandhu;Ran Oren.
American Journal of Pathology (2000)
Cell competition leads to a high level of normal liver reconstitution by transplanted fetal liver stem/progenitor cells.
Michael Oertel;Anuradha Menthena;Mariana D. Dabeva;David A. Shafritz.
Stem cells, cell transplantation and liver repopulation.
Michael Oertel;David A. Shafritz.
Biochimica et Biophysica Acta (2008)
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