World's Best Scientists 2026 revealed!
Amy Hin Yan Tong

Amy Hin Yan Tong

D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
20893
World Ranking
18531
National Ranking
647

Overview

Amy Hin Yan Tong is affiliated with the University of Toronto in Canada and works primarily within the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Genetics, Immunology, Oncology, and Infectious Diseases.

The scientist's publication record shows a focus on topics such as CRISPR and Genetic Engineering, Glioma Diagnosis and Treatment, Single-cell and Spatial Transcriptomics, RNA Research and Splicing, RNA and Protein Synthesis Mechanisms, Cancer Genomics and Diagnostics, and Immune Cell Function and Interaction.

Frequent coauthors in their work include Jason Moffat, Katherine Chan, Kevin R. Brown, Maximilian Billmann, and Chad L. Myers, indicating collaborative research efforts across multiple projects.

Their publications have appeared in a variety of scientific venues, with particular frequency in bioRxiv (Cold Spring Harbor Laboratory), Nature, Cancer Research, the Journal of Translational Genetics and Genomics, and G3 Genes Genomes Genetics.

Key recent papers include:

  • Functional genomic landscape of cancer-intrinsic evasion of killing by T cells (2020, Nature)
  • Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism (2020, Nature Metabolism)
  • A cohesin traffic pattern genetically linked to gene regulation (2022, Nature Structural & Molecular Biology)
  • FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation (2021, Nature)
  • N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity (2023, Nature Communications)

Best Publications

  • The genetic landscape of a cell.

    Michael Costanzo;Anastasia Baryshnikova;Jeremy Bellay;Yungil Kim

  • Global Mapping of the Yeast Genetic Interaction Network

    Amy Hin Yan Tong;Guillaume Lesage;Gary D. Bader;Huiming Ding

  • Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants

    Amy Hin Yan Tong;Marie Evangelista;Ainslie B. Parsons;Hong Xu

  • Navigating the Chaperone Network: An Integrative Map of Physical and Genetic Interactions Mediated by the Hsp90 Chaperone

    Rongmin Zhao;Mike Davey;Ya-Chieh Hsu;Pia Kaplanek

  • A Combined Experimental and Computational Strategy to Define Protein Interaction Networks for Peptide Recognition Modules

    Amy Hin Yan Tong;Becky Drees;Giuliano Nardelli;Gary D. Bader

  • Methylation of histone H3 by Set2 in Saccharomyces cerevisiae is linked to transcriptional elongation by RNA polymerase II.

    Nevan J. Krogan;Minkyu Kim;Amy Tong;Ashkan Golshani

  • A Snf2 family ATPase complex required for recruitment of the histone H2A variant Htz1.

    Nevan J. Krogan;Michael-Christopher Keogh;Nira Datta;Chika Sawa

  • Synthetic genetic array analysis in Saccharomyces cerevisiae.

    Amy Hin Yan Tong;Charles Boone

  • Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma

    Leilei Chen;Yan Li;Chi Ho Lin;Tim Hon Man Chan;Tim Hon Man Chan

  • A Conserved RING Finger Protein Required for Histone H2B Monoubiquitination and Cell Size Control.

    William W. Hwang;Shivkumar Venkatasubrahmanyam;Alexandra G. Ianculescu;Amy Tong

  • Evaluation and Design of Genome-Wide CRISPR/SpCas9 Knockout Screens.

    Traver Hart;Amy Hin Yan Tong;Katie Chan;Jolanda Van Leeuwen

  • Increased exonic de novo mutation rate in individuals with schizophrenia

    Simon L Girard;Julie Gauthier;Anne Noreau;Lan Xiong

  • Functional genomic landscape of cancer-intrinsic evasion of killing by T cells

    Keith A. Lawson;Keith A. Lawson;Cristovão M. Sousa;Xiaoyu Zhang;Eiru Kim

  • Comprehensive curation and analysis of global interaction networks in Saccharomyces cerevisiae

    Teresa Reguly;Ashton Breitkreutz;Lorrie Boucher;Bobby Joe Breitkreutz

  • A protein interaction map for cell polarity development

    Becky L. Drees;Bryan Sundin;Elizabeth Brazeau;Juliane P. Caviston

  • A Role for Myosin-I in Actin Assembly through Interactions with Vrp1p, Bee1p, and the Arp2/3 Complex

    Marie Evangelista;Bert M. Klebl;Amy H.Y. Tong;Bradley A. Webb

  • Combining biological networks to predict genetic interactions.

    Sharyl L. Wong;Lan V. Zhang;Amy H. Y. Tong;Zhijian Li

  • Analysis of the bacterial community in a laboratory-scale nitrification reactor and a wastewater treatment plant by 454-pyrosequencing

    Lin Ye;Ming-Fei Shao;Tong Zhang;Amy Hin Yan Tong

  • Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network

    Lan V Zhang;Oliver D King;Sharyl L Wong;Debra S Goldberg

  • Global Mapping of the Yeast Genetic Interaction Network: Discovering Gene and Drug Function

    Amy Tong;Guillaume Lesage;Ainslie Parsons;Brenda Andrews

Frequent Co-Authors

Charles Boone
Charles Boone University of Toronto
Jason Moffat
Jason Moffat University of Toronto
Brenda J. Andrews
Brenda J. Andrews University of Toronto
Gary D. Bader
Gary D. Bader University of Toronto
Chad L. Myers
Chad L. Myers University of Minnesota
Frederick P. Roth
Frederick P. Roth Lunenfeld-Tanenbaum Research Institute
Howard Bussey
Howard Bussey McGill University
Daniel Durocher
Daniel Durocher Lunenfeld-Tanenbaum Research Institute
Jack Greenblatt
Jack Greenblatt University of Toronto
Michael Costanzo
Michael Costanzo University of Toronto

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