D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics D-index 53 Citations 13,280 119 World Ranking 2936 National Ranking 109

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Enzyme

Grant W. Brown mainly investigates Genetics, Gene, Synthetic genetic array, Cell biology and Mutation. His work in Saccharomyces cerevisiae and Gene regulatory network are all subfields of Gene research. His research investigates the connection between Synthetic genetic array and topics such as Gene interaction that intersect with issues in Cullin, Phenotype, Genomics, Functional genomics and Ubiquitin ligase complex.

His Cell biology study integrates concerns from other disciplines, such as Eukaryotic DNA replication, DNA replication factor CDT1, Origin recognition complex, Control of chromosome duplication and DNA repair. His DNA repair research focuses on subjects like Immunoprecipitation, which are linked to DNA damage. He has researched Mutation in several fields, including Base excision repair, Establishment of sister chromatid cohesion, Chromatid, Fungal protein and Replication fork protection complex.

His most cited work include:

  • Global Mapping of the Yeast Genetic Interaction Network (1827 citations)
  • Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map (766 citations)
  • Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways (572 citations)

What are the main themes of his work throughout his whole career to date?

Grant W. Brown mainly focuses on Genetics, Cell biology, DNA replication, Gene and DNA damage. Genetics is a component of his Mutation, Synthetic genetic array, Genome, Functional genomics and Genomics studies. His Synthetic genetic array study combines topics in areas such as Gene interaction and Allele.

His Cell biology research includes elements of DNA re-replication, Eukaryotic DNA replication, CHEK1, DNA and Molecular biology. His work in Gene addresses issues such as Genome instability, which are connected to fields such as Homologous recombination and Helicase. His DNA damage study combines topics from a wide range of disciplines, such as Schizosaccharomyces pombe, Cancer research and DNA repair.

He most often published in these fields:

  • Genetics (38.89%)
  • Cell biology (38.10%)
  • DNA replication (33.33%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cell biology (38.10%)
  • DNA replication (33.33%)
  • Gene (26.98%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cell biology, DNA replication, Gene, Saccharomyces cerevisiae and Genome instability. His research in Cell biology intersects with topics in Ubiquitin, Ribosome and DNA, Endonuclease. His DNA replication research is multidisciplinary, incorporating perspectives in Sonic hedgehog, Cancer, Postreplication repair and Replication stress.

To a larger extent, Grant W. Brown studies Genetics with the aim of understanding Gene. The study incorporates disciplines such as Amino acid, Serine, Ploidy, Spindle pole body and Eukaryote in addition to Saccharomyces cerevisiae. The various areas that Grant W. Brown examines in his Genome instability study include Homologous recombination, Genome, Direct repeat, DNA mismatch repair and Computational biology.

Between 2017 and 2021, his most popular works were:

  • Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome (172 citations)
  • Systematic analysis of complex genetic interactions (120 citations)
  • The endonuclease cue2 cleaves mRNAs at stalled ribosomes during no go decay (65 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Enzyme

His primary areas of study are Cell biology, DNA, DNA damage, Gene and DNA replication. His study in Cell biology is interdisciplinary in nature, drawing from both Ribosome profiling, Ubiquitin and Messenger RNA. His work on Topoisomerase as part of general DNA study is frequently linked to RNA polymerase II and Cellular homeostasis, bridging the gap between disciplines.

His Gene study improves the overall literature in Genetics. In general Genetics, his work in Shu complex, Mutant and Methyl methanesulfonate is often linked to Zeocin linking many areas of study. His DNA replication research incorporates elements of Histone, Computational biology, Genome instability and Proliferating cell nuclear antigen.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Global Mapping of the Yeast Genetic Interaction Network

Amy Hin Yan Tong;Guillaume Lesage;Gary D. Bader;Huiming Ding.
Science (2004)

2447 Citations

Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map

Sean R. Collins;Kyle M. Miller;Nancy L. Maas;Assen Roguev.
Nature (2007)

990 Citations

Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways

Ainslie B Parsons;Renée L Brost;Huiming Ding;Zhijian Li.
Nature Biotechnology (2004)

722 Citations

Regulation of Chromosome Replication

Thomas J. Kelly;Grant W. Brown.
Annual Review of Biochemistry (2000)

536 Citations

Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress

Johnny M. Tkach;Askar Yimit;Anna Y. Lee;Michael Riffle.
Nature Cell Biology (2012)

472 Citations

Functional targeting of DNA damage to a nuclear pore-associated SUMO-dependent ubiquitin ligase.

Shigeki Nagai;Karine Dubrana;Monika Tsai-Pflugfelder;Marta B. Davidson.
Science (2008)

447 Citations

Quantitative analysis of fitness and genetic interactions in yeast on a genome scale

Anastasia Baryshnikova;Michael Costanzo;Yungil Kim;Huiming Ding.
Nature Methods (2010)

368 Citations

A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage.

Michael Chang;Mohammed Bellaoui;Charles Boone;Grant W. Brown.
Proceedings of the National Academy of Sciences of the United States of America (2002)

349 Citations

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

Hong Xu;Marco Di Antonio;Steven McKinney;Veena Mathew.
Nature Communications (2017)

329 Citations

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

Leonard Wu;Csanad Z. Bachrati;Jiongwen Ou;Chang Xu.
Proceedings of the National Academy of Sciences of the United States of America (2006)

295 Citations

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