World's Best Scientists 2026 revealed!
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Hiroshi Handa
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Genetics and Molecular Biology
Japan
2024

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Molecular Biology 98 573 512 42 38 546 35061

Hiroshi Handa publications per year

The chart shows the history of publications by Hiroshi Handa between 1961 and 2026, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Hiroshi Handa published across 66 years, from 1961 to 2026, averaging 10.4 papers a year. Output peaked at 38 publications in 2009. 10 of the 688 publications appeared in the last two years.

No. of publications
10 20 30
Bar chart. Horizontal axis: year, 1961 to 2026. Vertical axis: number of publications, 0 to 38. Peak 38 publications in 2009. 1961: 1 publication 1962: 0 publications 1963: 0 publications 1964: 0 publications 1965: 0 publications 1966: 0 publications 1967: 0 publications 1968: 0 publications 1969: 0 publications 1970: 0 publications 1971: 1 publication 1972: 0 publications 1973: 0 publications 1974: 0 publications 1975: 1 publication 1976: 1 publication 1977: 6 publications 1978: 1 publication 1979: 1 publication 1980: 2 publications 1981: 3 publications 1982: 0 publications 1983: 2 publications 1984: 2 publications 1985: 4 publications 1986: 5 publications 1987: 2 publications 1988: 5 publications 1989: 4 publications 1990: 4 publications 1991: 11 publications 1992: 7 publications 1993: 10 publications 1994: 17 publications 1995: 22 publications 1996: 18 publications 1997: 19 publications 1998: 22 publications 1999: 22 publications 2000: 17 publications 2001: 12 publications 2002: 15 publications 2003: 33 publications 2004: 26 publications 2005: 30 publications 2006: 29 publications 2007: 31 publications 2008: 20 publications 2009: 38 publications 2010: 21 publications 2011: 18 publications 2012: 15 publications 2013: 24 publications 2014: 21 publications 2015: 15 publications 2016: 22 publications 2017: 13 publications 2018: 11 publications 2019: 12 publications 2020: 16 publications 2021: 14 publications 2022: 5 publications 2023: 23 publications 2024: 4 publications 2025: 9 publications 2026: 1 publication
1961 2026

688 publications in total across all disciplines

View publications per year as a table
Hiroshi Handa: publications per year, 1961 to 2026
Year Publications
1961 1
1962 0
1963 0
1964 0
1965 0
1966 0
1967 0
1968 0
1969 0
1970 0
1971 1
1972 0
1973 0
1974 0
1975 1
1976 1
1977 6
1978 1
1979 1
1980 2
1981 3
1982 0
1983 2
1984 2
1985 4
1986 5
1987 2
1988 5
1989 4
1990 4
1991 11
1992 7
1993 10
1994 17
1995 22
1996 18
1997 19
1998 22
1999 22
2000 17
2001 12
2002 15
2003 33
2004 26
2005 30
2006 29
2007 31
2008 20
2009 38
2010 21
2011 18
2012 15
2013 24
2014 21
2015 15
2016 22
2017 13
2018 11
2019 12
2020 16
2021 14
2022 5
2023 23
2024 4
2025 9
2026 1
Total 688
Download as CSV

Hiroshi Handa publication distribution in Molecular Biology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Molecular Biology in 2026. The highlighted bar marks where Hiroshi Handa sits on this spectrum.

No. of scientists
50 100 150
Bar chart with 53 bars. Horizontal axis: publications, 47–56 to 564+. Vertical axis: number of scientists, 0 to 177. Most scientists, 177, have 117–126 publications. The last bar groups every scientist with 564 publications or more. The highlighted bar, 537–546 publications, is where this scientist sits. 47–56 publications: 7 scientists 57–66 publications: 17 scientists 67–76 publications: 65 scientists 77–86 publications: 90 scientists 87–96 publications: 125 scientists 97–106 publications: 131 scientists 107–116 publications: 162 scientists 117–126 publications: 177 scientists 127–136 publications: 158 scientists 137–146 publications: 158 scientists 147–156 publications: 146 scientists 157–166 publications: 159 scientists 167–176 publications: 131 scientists 177–186 publications: 110 scientists 187–196 publications: 112 scientists 197–206 publications: 100 scientists 207–216 publications: 89 scientists 217–226 publications: 98 scientists 227–236 publications: 74 scientists 237–246 publications: 72 scientists 247–256 publications: 63 scientists 257–266 publications: 53 scientists 267–276 publications: 54 scientists 277–286 publications: 49 scientists 287–296 publications: 52 scientists 297–306 publications: 43 scientists 307–316 publications: 46 scientists 317–326 publications: 41 scientists 327–336 publications: 42 scientists 337–346 publications: 31 scientists 347–356 publications: 28 scientists 357–366 publications: 29 scientists 367–376 publications: 26 scientists 377–386 publications: 24 scientists 387–396 publications: 24 scientists 397–406 publications: 14 scientists 407–416 publications: 13 scientists 417–426 publications: 20 scientists 427–436 publications: 12 scientists 437–446 publications: 20 scientists 447–456 publications: 11 scientists 457–466 publications: 10 scientists 467–476 publications: 14 scientists 477–486 publications: 14 scientists 487–496 publications: 10 scientists 497–506 publications: 13 scientists 507–516 publications: 13 scientists 517–526 publications: 2 scientists 527–536 publications: 4 scientists 537–546 publications: 6 scientists 547–556 publications: 8 scientists 557–563 publications: 6 scientists 564+ publications: 100 scientists
47–56 publications 564+

This scientist: 546 publications — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 564 publications or more.

View publications distribution as a table
Number of Molecular Biology scientists by publication count, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
Publications Scientists This scientist
47–56 7
57–66 17
67–76 65
77–86 90
87–96 125
97–106 131
107–116 162
117–126 177
127–136 158
137–146 158
147–156 146
157–166 159
167–176 131
177–186 110
187–196 112
197–206 100
207–216 89
217–226 98
227–236 74
237–246 72
247–256 63
257–266 53
267–276 54
277–286 49
287–296 52
297–306 43
307–316 46
317–326 41
327–336 42
337–346 31
347–356 28
357–366 29
367–376 26
377–386 24
387–396 24
397–406 14
407–416 13
417–426 20
427–436 12
437–446 20
447–456 11
457–466 10
467–476 14
477–486 14
487–496 10
497–506 13
507–516 13
517–526 2
527–536 4
537–546 6 546
547–556 8
557–563 6
564+ 100
Download as CSV

Hiroshi Handa D-index placement in Molecular Biology in 2026

The chart shows the D-index (discipline H-index) distribution of Molecular Biology scientists ranked by Research.com in 2026. The highlighted bar marks where Hiroshi Handa sits on this spectrum.

No. of scientists
25 50 75 100 125
Bar chart with 54 bars. Horizontal axis: D-Index, 40–41 to 145+. Vertical axis: number of scientists, 0 to 131. Most scientists, 131, have 64–65 D-Index. The last bar groups every scientist with 145 D-Index or more. The highlighted bar, 98–99 D-Index, is where this scientist sits. 40–41 D-Index: 36 scientists 42–43 D-Index: 101 scientists 44–45 D-Index: 115 scientists 46–47 D-Index: 121 scientists 48–49 D-Index: 118 scientists 50–51 D-Index: 130 scientists 52–53 D-Index: 106 scientists 54–55 D-Index: 116 scientists 56–57 D-Index: 113 scientists 58–59 D-Index: 129 scientists 60–61 D-Index: 120 scientists 62–63 D-Index: 105 scientists 64–65 D-Index: 131 scientists 66–67 D-Index: 95 scientists 68–69 D-Index: 97 scientists 70–71 D-Index: 106 scientists 72–73 D-Index: 83 scientists 74–75 D-Index: 89 scientists 76–77 D-Index: 77 scientists 78–79 D-Index: 70 scientists 80–81 D-Index: 73 scientists 82–83 D-Index: 60 scientists 84–85 D-Index: 48 scientists 86–87 D-Index: 45 scientists 88–89 D-Index: 50 scientists 90–91 D-Index: 31 scientists 92–93 D-Index: 51 scientists 94–95 D-Index: 43 scientists 96–97 D-Index: 38 scientists 98–99 D-Index: 39 scientists 100–101 D-Index: 41 scientists 102–103 D-Index: 29 scientists 104–105 D-Index: 33 scientists 106–107 D-Index: 35 scientists 108–109 D-Index: 20 scientists 110–111 D-Index: 38 scientists 112–113 D-Index: 19 scientists 114–115 D-Index: 28 scientists 116–117 D-Index: 13 scientists 118–119 D-Index: 23 scientists 120–121 D-Index: 16 scientists 122–123 D-Index: 15 scientists 124–125 D-Index: 11 scientists 126–127 D-Index: 21 scientists 128–129 D-Index: 7 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 14 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 9 scientists 138–139 D-Index: 8 scientists 140–141 D-Index: 16 scientists 142–143 D-Index: 7 scientists 144 D-Index: 7 scientists 145+ D-Index: 100 scientists
40–41 D-Index 145+

This scientist: 98 D-Index — 82nd percentile

82% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 145 D-Index or more.

View D-Index distribution as a table
Number of Molecular Biology scientists by D-index, Research.com 2026 ranking edition. Based on 3,076 ranked scientists.
D-Index Scientists This scientist
40–41 36
42–43 101
44–45 115
46–47 121
48–49 118
50–51 130
52–53 106
54–55 116
56–57 113
58–59 129
60–61 120
62–63 105
64–65 131
66–67 95
68–69 97
70–71 106
72–73 83
74–75 89
76–77 77
78–79 70
80–81 73
82–83 60
84–85 48
86–87 45
88–89 50
90–91 31
92–93 51
94–95 43
96–97 38
98–99 39 98
100–101 41
102–103 29
104–105 33
106–107 35
108–109 20
110–111 38
112–113 19
114–115 28
116–117 13
118–119 23
120–121 16
122–123 15
124–125 11
126–127 21
128–129 7
130–131 13
132–133 14
134–135 17
136–137 9
138–139 8
140–141 16
142–143 7
144 7
145+ 100
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Research.com Recognitions

  • 2024 - Research.com Genetics and Molecular Biology in Japan Leader Award

Overview

Hiroshi Handa is affiliated with Tokyo Medical University in Japan. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong emphasis on molecular biology, hematology, and neurology. Their work also intersects related subfields such as genetics and immunology.

Handa's main research topics include multiple myeloma research and treatments, protein degradation and inhibitors, amyotrophic lateral sclerosis (ALS) research, ubiquitin and proteasome pathways, neurogenetic and muscular disorders research, histone deacetylase inhibitors research, and platelet disorders and treatments.

Frequent collaborators in Handa's research activities include Takumi Ito, Kazuhide Asakawa, Koichi Kawakami, Junichi Yamamoto, and Yuki Yamaguchi. Their scholarly output features publications in several recurrent venues, with multiple articles published in Clinical Lymphoma Myeloma & Leukemia, Nature Communications, Cancers, Scientific Reports, and Communications Biology.

Among recent notable publications are:

  • "Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders" (2022), published in Chemical Society Reviews
  • "Molecular mechanisms of thalidomide and its derivatives" (2020), published in Proceedings of the Japan Academy Series B
  • "ARID2 is a pomalidomide-dependent CRL4CRBN substrate in multiple myeloma cells" (2020), published in Nature Chemical Biology
  • "Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons" (2020), published in Nature Communications
  • "Molecular Mechanisms of the Teratogenic Effects of Thalidomide" (2020), published in Pharmaceuticals

Handa's research contributions cover molecular mechanisms related to thalidomide and its derivatives, their impact on protein degradation pathways, and neurological disease mechanisms, particularly ALS. The scientist's work also includes investigations on the substrates targeted by cereblon (CRBN), which plays a role in the therapeutic effects of immunomodulatory drugs used in multiple myeloma.

Best Publications

  • Identification of a Primary Target of Thalidomide Teratogenicity

    Takumi Ito;Hideki Ando;Takayuki Suzuki;Toshihiko Ogura

  • NELF, a Multisubunit Complex Containing RD, Cooperates with DSIF to Repress RNA Polymerase II Elongation

    Yuki Yamaguchi;Toshiyuki Takagi;Tadashi Wada;Keiichi Yano

  • An SV40-immortalized human corneal epithelial cell line and its characterization.

    K Araki-Sasaki;Y Ohashi;T Sasabe;K Hayashi

  • DSIF, A NOVEL TRANSCRIPTION ELONGATION FACTOR THAT REGULATES RNA POLYMERASE II PROCESSIVITY, IS COMPOSED OF HUMAN SPT4 AND SPT5 HOMOLOGS

    Tadashi Wada;Toshiyuki Takagi;Yuki Yamaguchi;Anwarul Ferdous

  • Cereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide.

    A Lopez-Girona;D Mendy;T Ito;K Miller

  • A common trans-acting factor, Ad4-binding protein, to the promoters of steroidogenic P-450s

    Ken-Ichirou Morohashi;Shin Ichiro Honda;Yukio Inomata;Hiroshi Handa

  • Redox regulation of NF-κB activation: Distinct redox regulation between the cytoplasm and the nucleus

    Yasuaki Kabe;Kozue Ando;Satoshi Hirao;Makoto Yoshida

  • Immunomodulatory agents lenalidomide and pomalidomide co-stimulate T cells by inducing degradation of T cell repressors Ikaros and Aiolos via modulation of the E3 ubiquitin ligase complex CRL4(CRBN.).

    Anita K Gandhi;Jian Kang;Courtney G Havens;Thomas Conklin

  • Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.

    Grant A. Hartzog;Tadashi Wada;Hiroshi Handa;Fred Winston

  • EVIDENCE THAT P-TEFB ALLEVIATES THE NEGATIVE EFFECT OF DSIF ON RNA POLYMERASE II-DEPENDENT TRANSCRIPTION IN VITRO

    Tadashi Wada;Toshiyuki Takagi;Yuki Yamaguchi;Daisuke Watanabe

  • A novel cereblon modulator recruits GSPT1 to the CRL4 CRBN ubiquitin ligase

    Mary E. Matyskiela;Gang Lu;Takumi Ito;Barbra Pagarigan

  • P-TEFb-mediated phosphorylation of hSpt5 C-terminal repeats is critical for processive transcription elongation.

    Tomoko Yamada;Yuki Yamaguchi;Yuki Yamaguchi;Naoto Inukai;Sachiko Okamoto

  • Structure of the human Cereblon–DDB1–lenalidomide complex reveals basis for responsiveness to thalidomide analogs

    Philip P Chamberlain;Antonia Lopez-Girona;Karen Miller;Gilles Carmel

  • MafA Is a Glucose-regulated and Pancreatic β-Cell-specific Transcriptional Activator for the Insulin Gene

    Kohsuke Kataoka;Song-iee Han;Setsuko Shioda;Momoki Hirai

  • NELF and DSIF cause promoter proximal pausing on the hsp70 promoter in Drosophila

    Chwen Huey Wu;Yuki Yamaguchi;Lawrence R. Benjamin;Maria Horvat-Gordon

  • Mutations of the PAX6 Gene Detected in Patients with a Variety of Optic-Nerve Malformations

    Noriyuki Azuma;Yuki Yamaguchi;Hiroshi Handa;Keiko Tadokoro

  • High-performance affinity beads for identifying drug receptors

    Noriaki Shimizu;Kotaro Sugimoto;Jianwei Tang;Takeyuki Nishi

  • Evidence that Negative Elongation Factor Represses Transcription Elongation through Binding to a DRB Sensitivity-Inducing Factor/RNA Polymerase II Complex and RNA

    Yuki Yamaguchi;Naoto Inukai;Takashi Narita;Tadashi Wada

  • Human transcription elongation factor NELF: identification of novel subunits and reconstitution of the functionally active complex.

    Takashi Narita;Yuki Yamaguchi;Keiichi Yano;Seiji Sugimoto

  • Mediator requirement for both recruitment and postrecruitment steps in transcription initiation.

    Gang Wang;Michael A. Balamotis;Jennitte L. Stevens;Yuki Yamaguchi

Frequent Co-Authors

Yuki Yamaguchi
Yuki Yamaguchi Tokyo Institute of Technology
Hajime Watanabe
Hajime Watanabe Osaka University
Haruma Kawaguchi
Haruma Kawaguchi Keio University
Jun-ichi Sawada
Jun-ichi Sawada University of Shizuoka
Makoto Suematsu
Makoto Suematsu Keio University
Hirotoshi Tanaka
Hirotoshi Tanaka Keio University
Kyosuke Nagata
Kyosuke Nagata University of Tsukuba
Phillip A. Sharp
Phillip A. Sharp MIT
Koichi Kawakami
Koichi Kawakami National Institute of Genetics
Taisen Iguchi
Taisen Iguchi National Institute for Basic Biology

External Links

Personal website of Hiroshi Handa

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Best Scientists Citing Hiroshi Handa

Kyosuke Nagata

Kyosuke Nagata

University of Tsukuba

Publications: 60

John T. Lis

John T. Lis

Cornell University

Publications: 49

David H. Price

David H. Price

University of Iowa

Publications: 46

Patrick Cramer

Patrick Cramer

Max Planck Society

Publications: 45

Benjamin L. Ebert

Benjamin L. Ebert

Harvard University

Publications: 41

Ken-ichirou Morohashi

Ken-ichirou Morohashi

Kyushu University

Publications: 37

B. Matija Peterlin

B. Matija Peterlin

University of California, San Francisco

Publications: 33

Mark R. Kelley

Mark R. Kelley

Indiana University

Publications: 33

Karen Adelman

Karen Adelman

Harvard University

Publications: 32

Ali Shilatifard

Ali Shilatifard

Northwestern University

Publications: 31

May Griffith

May Griffith

University of Montreal

Publications: 31

Teruo Nishida

Teruo Nishida

Yamaguchi University

Publications: 30

Craig M. Crews

Craig M. Crews

Yale University

Publications: 30

Joan Weliky Conaway

Joan Weliky Conaway

The University of Texas Southwestern Medical Center

Publications: 29

Taisen Iguchi

Taisen Iguchi

National Institute for Basic Biology

Publications: 26

Robert P. Fisher

Robert P. Fisher

Icahn School of Medicine at Mount Sinai

Publications: 26

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