World's Best Scientists 2026 revealed!
Makoto Suematsu

Makoto Suematsu

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Biology and Biochemistry
Japan
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
108
Citations
40831
World Ranking
1053
National Ranking
55

Medicine

D-Index
108
Citations
41121
World Ranking
6026
National Ranking
133

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2025 - Research.com Biology and Biochemistry in Japan Leader Award
  • 2023 - Research.com Biology and Biochemistry in Japan Leader Award

Overview

Makoto Suematsu is affiliated with Keio University in Japan and has a research focus spanning Medicine and Biochemistry, Genetics, and Molecular Biology. Their scholarly output includes significant contributions to molecular biology, immunology, physiology, surgery, and cancer research.

The research topics they cover include:

  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation
  • Pancreatic function and diabetes
  • SARS-CoV-2 and COVID-19 Research
  • Gut microbiota and health
  • Immune Cell Function and Interaction
  • Hormonal Regulation and Hypertension

Among recent publications are the following papers:

  • Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians, 2021, Nature
  • Restoring metabolism of myeloid cells reverses cognitive decline in ageing, 2021, Nature
  • B cell-derived GABA elicits IL-10+ macrophages to limit anti-tumour immunity, 2021, Nature
  • Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders, 2021, Science
  • Gut bacteria identified in colorectal cancer patients promote tumourigenesis via butyrate secretion, 2021, Nature Communications

The frequent co-authors with whom Suematsu has collaborated include:

  • Yuki Sugiura
  • Yasuaki Kabe
  • Takako Hishiki
  • Takehiro Yamamoto
  • Keiyo Takubo

The venues where their work is most frequently published include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • iScience
  • Scientific Reports
  • Nature

Best Publications

  • CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

    Takatsugu Ishimoto;Osamu Nagano;Toshifumi Yae;Mayumi Tamada

  • Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes.

    Shugo Tohyama;Fumiyuki Hattori;Motoaki Sano;Takako Hishiki

  • A defined commensal consortium elicits CD8 T cells and anti-cancer immunity

    Takeshi Tanoue;Satoru Morita;Damian R. Plichta;Ashwin N. Skelly

  • Regulation of the HIF-1α level is essential for hematopoietic stem cells

    Keiyo Takubo;Nobuhito Goda;Wakako Yamada;Hirono Iriuchishima

  • Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.

    Tomoaki Ida;Tomohiro Sawa;Hideshi Ihara;Yukihiro Tsuchiya

  • Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption.

    Tomoyoshi Soga;Richard Baran;Makoto Suematsu;Yuki Ueno

  • Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells

    Keiyo Takubo;Go Nagamatsu;Chiharu I. Kobayashi;Ayako Nakamura-Ishizu

  • Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians

    Yuko Sato;Koji Atarashi;Damian R. Plichta;Yasumichi Arai

  • Crosstalk between Glucocorticoid Receptor and Nutritional Sensor mTOR in Skeletal Muscle

    Noriaki Shimizu;Noritada Yoshikawa;Naoki Ito;Takako Maruyama

  • Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver.

    Makoto Suematsu;Nobuhito Goda;Tsuyoshi Sano;Satoshi Kashiwagi

  • Restoring metabolism of myeloid cells reverses cognitive decline in ageing

    Paras S. Minhas;Amira Latif-Hernandez;Melanie R. McReynolds;Aarooran S. Durairaj

  • Hypoxia-Sensitive Fluorescent Probes for in Vivo Real-Time Fluorescence Imaging of Acute Ischemia

    Kazuki Kiyose;Kenjiro Hanaoka;Daihi Oushiki;Tomomi Nakamura

  • Induction of Heme Oxygenase-1 Suppresses Venular Leukocyte Adhesion Elicited by Oxidative Stress Role of Bilirubin Generated by the Enzyme

    Shinobu Hayashi;Rina Takamiya;Tokio Yamaguchi;Kenji Matsumoto

  • Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue.

    Yoichi Imaizumi;Yohei Okada;Wado Akamatsu;Masato Koike

  • The Reconstituted ‘Humanized Liver’ in TK-NOG Mice is Mature and Functional

    Masami Hasegawa;Kenji Kawai;Tetsuya Mitsui;Kenji Taniguchi;Kenji Taniguchi

  • Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

    Toshifumi Yae;Toshifumi Yae;Kenji Tsuchihashi;Takatsugu Ishimoto;Takeshi Motohara

  • Interactions of multiple gas-transducing systems: hallmarks and uncertainties of CO, NO, and H2S gas biology.

    Mayumi Kajimura;Ryo Fukuda;Ryon M. Bateman;Takehiro Yamamoto

  • Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation.

    Nobuhito Goda;Kensuke Suzuki;Makoto Naito;Shinji Takeoka

  • Peyer's patch is the essential site in initiating murine acute and lethal graft-versus-host reaction.

    Masako Murai;Hiroyuki Yoneyama;Hiroyuki Yoneyama;Taichi Ezaki;Makoto Suematsu

  • ERK and p38 MAPK, but not NF-κB, are critically involved in reactive oxygen species-mediated induction of IL-6 by angiotensin II in cardiac fibroblasts

    Motoaki Sano;Keiichi Fukuda;Toshihiko Sato;Haruko Kawaguchi

Frequent Co-Authors

Yuki Sugiura
Yuki Sugiura Keio University
Yuzuru Ishimura
Yuzuru Ishimura Keio University
Hidekazu Suzuki
Hidekazu Suzuki Tokai University
Tomoyoshi Soga
Tomoyoshi Soga Keio University
Hiromasa Ishii
Hiromasa Ishii Keio University
Keiichi Fukuda
Keiichi Fukuda Keio University
Dai Fukumura
Dai Fukumura Harvard University
Hideyuki Saya
Hideyuki Saya Fujita Health University
Geert W. Schmid-Schönbein
Geert W. Schmid-Schönbein University of California, San Diego
Tomoyoshi Nozaki
Tomoyoshi Nozaki University of Tokyo

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