World's Best Scientists 2026 revealed!
Yuzuru Ishimura

Yuzuru Ishimura

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
10751
World Ranking
14475
National Ranking
1019

Overview

Yuzuru Ishimura is a researcher affiliated with Keio University in Japan. Their academic work primarily focuses on the fields of biochemistry, genetics, and molecular biology, with a particular emphasis on pharmacogenetics and drug metabolism, metabolomics and mass spectrometry studies, and metabolism and genetic disorders.

Their research contributions have been published in notable scientific venues, including:

  • The Journal of Biochemistry
  • Inflammation and Regeneration

Yuzuru Ishimura has coauthored academic papers with a range of colleagues, including:

  • Ken-ichirou Morohashi
  • Bin Wu
  • Shigeyuki Shichino
  • Satoshi Ueha
  • Rina Matsukiyo

Two recent papers illustrate their active involvement in molecular biology and inflammation research:

  • "Obituary IN MEMORY OF A HUMBLE SCIENTIFIC PIONEER, TSUNEO OMURA (1930-2022)," published in 2022 in The Journal of Biochemistry
  • "Ex vivo lung-organoid model for aberrant basaloid cell induction and activation," published in 2025 in Inflammation and Regeneration

The scientist's subfields of study expand on pharmacology, molecular biology, and clinical biochemistry, reflecting a cross-disciplinary approach to understanding biochemical processes and pathological mechanisms.

The focus on pharmacogenetics and drug metabolism demonstrates their involvement in understanding genetic influences on drug response. Their work in metabolomics and mass spectrometry studies underpins efforts to characterize metabolic profiles related to disease and experimental models. The areas of metabolism and genetic disorders tie into broader interests in genetic regulation and biochemical pathways.

Best Publications

  • The low-spin heme of cytochrome c oxidase as the driving element of the proton-pumping process

    Tomitake Tsukihara;Kunitoshi Shimokata;Yukie Katayama;Hideo Shimada

  • Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation.

    Michiyo Imai;Hideo Shimada;Yoshihito Watanabe;Yuko Matsushima-Hibiya

  • Carbon monoxide: an endogenous modulator of sinusoidal tone in the perfused rat liver.

    Makoto Suematsu;Nobuhito Goda;Tsuyoshi Sano;Satoshi Kashiwagi

  • Induction of Heme Oxygenase-1 Suppresses Venular Leukocyte Adhesion Elicited by Oxidative Stress Role of Bilirubin Generated by the Enzyme

    Shinobu Hayashi;Rina Takamiya;Tokio Yamaguchi;Kenji Matsumoto

  • Distribution of heme oxygenase isoforms in rat liver. Topographic basis for carbon monoxide-mediated microvascular relaxation.

    Nobuhito Goda;Kensuke Suzuki;Makoto Naito;Shinji Takeoka

  • Activation of a suicide process of thymocytes through DNA fragmentation by calcium ionophores and phorbol esters.

    H Kizaki;T Tadakuma;C Odaka;J Muramatsu

  • Zone-specific expression of aldosterone synthase cytochrome P-450 and cytochrome P-45011 beta in rat adrenal cortex: histochemical basis for the functional zonation.

    Tadashi Ogishima;Hiroshi Suzuki;Jun Ichi Hata;Fumiko Mitani

  • Carbon monoxide as an endogenous modulator of hepatic vascular perfusion.

    Makoto Suematsu;Satoshi Kashiwagi;Tsuyoshi Sano;Nobuhito Goda

  • A novel cell layer without corticosteroid-synthesizing enzymes in rat adrenal cortex: Histochemical detection and possible physiological role

    Fumiko Mitani;Hiroshi Suzuki;Jun Ichi Hata;Tadashi Ogishima

  • Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism

    Tadashi Ogishima;H. Shibata;H. Shimada;F. Mitani

  • Isolation of aldosterone synthase cytochrome P-450 from zona glomerulosa mitochondria of rat adrenal cortex.

    Tadashi Ogishima;F. Mitani;Y. Ishimura

  • Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver.

    Takanori Kyokane;Shinji Norimizu;Hisashi Taniai;Tokio Yamaguchi

  • Stoichiometric conversion of oxygen to superoxide anion during the respiratory burst in neutrophils. Direct evidence by a new method for measurement of superoxide anion with diacetyldeuteroheme-substituted horseradish peroxidase.

    R Makino;T Tanaka;T Iizuka;Y Ishimura

  • Adenosine receptor-mediated accumulation of cyclic AMP-induced T-lymphocyte death through internucleosomal DNA cleavage.

    H Kizaki;K Suzuki;T Tadakuma;Y Ishimura

  • Protective roles of endogenous carbon monoxide in neointimal development elicited by arterial injury

    Yuko Togane;Toshisuke Morita;Makoto Suematsu;Yuzuru Ishimura

  • The heme oxygenase-carbon monoxide system: a regulator of hepatobiliary function.

    Makoto Suematsu;Yuzuru Ishimura

  • Formation of Compound I in the Reaction of Native Myoglobins with Hydrogen Peroxide

    Tsuyoshi Egawa;Hideo Shimada;Yuzuru Ishimura

  • Gaseous monoxides: A new class of microvascular regulator in the liver

    Makoto Suematsu;Yoshiyuki Wakabayashi;Yuzuru Ishimura

  • Development of functional zonation in the rat adrenal cortex.

    Fumiko Mitani;Kuniaki Mukai;Hirokuni Miyamoto;Makoto Suematsu

  • Molecular cloning of a cDNA encoding aldosterone synthase cytochrome P-450 in rat adrenal cortex

    Michiyo Imai;Hideo Shimada;Yukiko Okada;Yuko Matsushima-Hibiya

Frequent Co-Authors

Makoto Suematsu
Makoto Suematsu Keio University
Yoshihito Watanabe
Yoshihito Watanabe Nagoya University
Takuya Tamatani
Takuya Tamatani Japan Tobacco (United States)
Yuji Nimura
Yuji Nimura Nagoya University
Eishun Tsuchida
Eishun Tsuchida Waseda University
Takao Saruta
Takao Saruta Keio University
Teizo Kitagawa
Teizo Kitagawa University of Hyogo
Shinji Takeoka
Shinji Takeoka Waseda University
Yoshitsugu Shiro
Yoshitsugu Shiro University of Hyogo
Makoto Naito
Makoto Naito Niigata University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry opens doors to a variety of online degrees and health science career options. Many students considering these fields are interested in hands-on patient care, research, or allied health professions. Flexible educational paths make these goals more accessible, especially if you need to balance studies with work or family.

For those aiming to connect biology with nutrition, enrolling in the top dietetics masters programs can lead to specialized clinical and research roles. If you want to start working in healthcare quickly, consider online medical assistant programs with financial aid, which provide both convenience and support.

Want to advance from a medical assistant role? MA to LPN bridge programs online offer a fast-track route to becoming a Licensed Practical Nurse. Alternatively, for those interested in life sciences careers or graduate study, an online biology bachelor's degree can provide in-depth scientific training with the speed of accelerated courses.

Each pathway is designed to help you build a flexible, rewarding career in the biomedical and health sciences fields.

Best Scientists Citing Yuzuru Ishimura

Recently Published Articles