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Koichiro Ishimori

Koichiro Ishimori

D-Index & Metrics

Chemistry

D-Index
47
Citations
6645
World Ranking
15785
National Ranking
1243

Overview

Koichiro Ishimori is affiliated with Hokkaido University in Japan and has a research focus primarily in the field of Biochemistry, Genetics and Molecular Biology. Their work spans a range of subfields, including Molecular Biology, Cellular and Molecular Neuroscience, Cell Biology, Materials Chemistry, and Immunology.

The scientist's research interests reflect a concentration on several main topics, such as:

  • Heat shock proteins research
  • Protein Structure and Dynamics
  • Photosynthetic Processes and Mechanisms
  • Photoreceptor and optogenetics research
  • Enzyme Structure and Function
  • Hemoglobin structure and function
  • Spectroscopy and Quantum Chemical Studies

Koichiro Ishimori has contributed to various scientific papers published mainly between 2020 and 2023. Notable recent publications include:

  • "C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers," 2021, Nature Communications
  • "Functional cooperativity between the trigger factor chaperone and the ClpXP proteolytic complex," 2021, Nature Communications
  • "Unveiling the impact of oxidation-driven endogenous protein interactions on the dynamics of amyloid-β aggregation and toxicity," 2023, Chemical Science
  • "Mechanistic insights into heme-mediated transcriptional regulation via a bacterial manganese-binding iron regulator, iron response regulator (Irr)," 2020, Journal of Biological Chemistry
  • "Radical transfer but not heme distal residues is essential for pH dependence of dye-decolorizing activity of peroxidase from Vibrio cholerae," 2021, Journal of Inorganic Biochemistry

The frequent coauthors collaborating with Ishimori include:

  • Tomohide Saio
  • Takeshi Uchida
  • Soichiro Kawagoe
  • Hiroyuki Kumeta
  • Motonori Matsusaki

The scientist's work has appeared most frequently in these publication venues:

  • ECS Meeting Abstracts
  • Nature Communications
  • Journal of Inorganic Biochemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biophysical Journal

Best Publications

  • Conformational landscape of cytochrome c folding studied by microsecond-resolved small-angle x-ray scattering.

    Shuji Akiyama;Satoshi Takahashi;Tetsunari Kimura;Koichiro Ishimori

  • Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase.

    Shin Ichi Adachi;Shingo Nagano;Koichiro Ishimori;Yoshihito Watanabe

  • Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.

    Koji Yamanaka;Haruto Ishikawa;Haruto Ishikawa;Yuzuru Megumi;Fuminori Tokunaga

  • Stepwise formation of alpha-helices during cytochrome c folding.

    Shuji Akiyama;Satoshi Takahashi;Koichiro Ishimori;Isao Morishima

  • Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance

    Yasuaki Kabe;Takanori Nakane;Ikko Koike;Tatsuya Yamamoto

  • Involvement of Heme Regulatory Motif in Heme-Mediated Ubiquitination and Degradation of IRP2

    Haruto Ishikawa;Michiko Kato;Hiroshi Hori;Koichiro Ishimori

  • Collapse and search dynamics of apomyoglobin folding revealed by submillisecond observations of α-helical content and compactness

    Takanori Uzawa;Shuji Akiyama;Tetsunari Kimura;Satoshi Takahashi

  • Roles of the axial push effect in cytochrome P450cam studied with the site-directed mutagenesis at the heme proximal site

    Shiro Yoshioka;Satoshi Takahashi;Koichiro Ishimori;Isao Morishima

  • Roles of the proximal hydrogen bonding network in cytochrome P450cam-catalyzed oxygenation.

    Shiro Yoshioka;Takehiko Tosha;Satoshi Takahashi;Koichiro Ishimori

  • Catalytic Roles of the Distal Site Asparagine−Histidine Couple in Peroxidases†

    Shingo Nagano;Motomasa Tanaka;Koichiro Ishimori;Yoshihito Watanabe

  • Two Heme Binding Sites Are Involved in the Regulated Degradation of the Bacterial Iron Response Regulator (Irr) Protein

    Jianhua Yang;Koichiro Ishimori;Mark R. O'Brian

  • Hierarchical folding mechanism of apomyoglobin revealed by ultra-fast H/D exchange coupled with 2D NMR

    Takanori Uzawa;Chiaki Nishimura;Shuji Akiyama;Koichiro Ishimori;Koichiro Ishimori

  • Specific collapse followed by slow hydrogen-bond formation of β-sheet in the folding of single-chain monellin

    Tetsunari Kimura;Takanori Uzawa;Koichiro Ishimori;Isao Morishima

  • Alteration of human myoglobin proximal histidine to cysteine or tyrosine by site-directed mutagenesis: characterization and their catalytic activities.

    Shin-ichi Adachi;Shingo Nagano;Yoshihito Watanabe;Koichiro Ishimori

  • Effects of Concerted Hydrogen Bonding of Distal Histidine on Active Site Structures of Horseradish Peroxidase. Resonance Raman Studies with Asn70 Mutants

    Masahiro Mukai;Shingo Nagano;Motomasa Tanaka;Koichiro Ishimori

  • Catalytic activities and structural properties of horseradish peroxidase distal His42 --> Glu or Gln mutant.

    Motomasa Tanaka;Koichiro Ishimori;Masahiro Mukai;Teizo Kitagawa

  • Direct electron transfer catalysed by recombinant forms of horseradish peroxidase: insight into the mechanism

    Annika Lindgren;Motomasa Tanaka;Tautgirdas Ruzgas;Lo Gorton

  • Preparation and reactions of myoglobin mutants bearing both proximal cysteine ligand and hydrophobic distal cavity: protein models for the active site of P-450.

    Toshitaka Matsui;Shingo Nagano;Koichiro Ishimori;Yoshihito Watanabe

  • Cerebral oxygen utilization analyzed by the use of oxygen-17 and its nuclear magnetic resonance

    Toshiyuki Arai;Shin-ichi Nakao;Kenjiro Mori;Koichiro Ishimori

  • A Dye-Decolorizing Peroxidase from Vibrio cholerae

    Takeshi Uchida;Miho Sasaki;Yoshikazu Tanaka;Koichiro Ishimori

  • Identification of histidine 77 as the axial heme ligand of carbonmonoxy CooA by picosecond time-resolved resonance Raman spectroscopy.

    Takeshi Uchida;Haruto Ishikawa;Koichiro Ishimori;Isao Morishima

Frequent Co-Authors

Isao Morishima
Isao Morishima Kyoto University
Satoshi Takahashi
Satoshi Takahashi Tohoku University
Teizo Kitagawa
Teizo Kitagawa University of Hyogo
Kazuhiro Iwai
Kazuhiro Iwai Kyoto University
Yoshihito Watanabe
Yoshihito Watanabe Nagoya University
Fuyuhiko Inagaki
Fuyuhiko Inagaki Hokkaido University
Kenji Inaba
Kenji Inaba University of Southern California
Shinya Yoshikawa
Shinya Yoshikawa University of Hyogo
Yoshinao Wada
Yoshinao Wada Osaka Women's and Children's Hospital
Yoshikazu Tanaka
Yoshikazu Tanaka Tohoku University

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