Isao Morishima

Overview

Best Publications

• Conformational landscape of cytochrome c folding studied by microsecond-resolved small-angle x-ray scattering.

  Shuji Akiyama;Satoshi Takahashi;Tetsunari Kimura;Koichiro Ishimori

  322
  Citations

• Roles of proximal ligand in heme proteins: replacement of proximal histidine of human myoglobin with cysteine and tyrosine by site-directed mutagenesis as models for P-450, chloroperoxidase, and catalase.

  Shin Ichi Adachi;Shingo Nagano;Koichiro Ishimori;Yoshihito Watanabe

  321
  Citations

• Oxidized Human Neuroglobin Acts as a Heterotrimeric Gα Protein Guanine Nucleotide Dissociation Inhibitor

  Keisuke Wakasugi;Keisuke Wakasugi;Tomomi Nakano;Isao Morishima

  271
  Citations

• Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2.

  Koji Yamanaka;Haruto Ishikawa;Haruto Ishikawa;Yuzuru Megumi;Fuminori Tokunaga

  229
  Citations

• Stepwise formation of alpha-helices during cytochrome c folding.

  Shuji Akiyama;Satoshi Takahashi;Koichiro Ishimori;Isao Morishima

  214
  Citations

• Collapse and search dynamics of apomyoglobin folding revealed by submillisecond observations of α-helical content and compactness

  Takanori Uzawa;Shuji Akiyama;Tetsunari Kimura;Satoshi Takahashi

  184
  Citations

• Direct observation of the push effect on the oxygen-oxygen bond cleavage of acylperoxoiron(III) porphyrin complexes

  Kazuya Yamaguchi;Yoshihito Watanabe;Isao Morishima

  175
  Citations

• Acylperoxo-Iron(III) Porphyrin Complexes: A New Entry of Potent Oxidants for the Alkene Epoxidation

  Kenji Machii;Yoshihito Watanabe;Isao Morishima

  174
  Citations

• Intra- and intermolecular beta-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases

  Motomasa Tanaka;Isao Morishima;Takumi Akagi;Tsutomu Hashikawa

  152
  Citations

• Effect of the heavy atom on the nuclear shielding constant. I. The proton chemical shifts in hydrogen halides

  Isao Morishima;Kazunaka Endo;Teijiro Yonezawa

  148
  Citations

• Presence of endogenous calcium ion and its functional and structural regulation in horseradish peroxidase.

  Y Shiro;M Kurono;I Morishima

  144
  Citations

• Characterisation of partially purified milk-clotting enzyme from Solanum dubium Fresen seeds

  Isam Ali Mohamed Ahmed;Isao Morishima;Elfadil E. Babiker;Elfadil E. Babiker;Nobuhiro Mori

  143
  Citations

• Roles of the axial push effect in cytochrome P450cam studied with the site-directed mutagenesis at the heme proximal site

  Shiro Yoshioka;Satoshi Takahashi;Koichiro Ishimori;Isao Morishima

  141
  Citations

• Conformational dependence of the inductive effect in the .sigma.-electron system as studied by carbon-13 nuclear magnetic resonance

  Isao. Morishima;Kenichi. Yoshikawa;Koji. Okada;Teijiro. Yonezawa

  139
  Citations

• NO Reduction by Nitric-oxide Reductase from Denitrifying Bacterium Pseudomonas aeruginosa CHARACTERIZATION OF REACTION INTERMEDIATES THAT APPEAR IN THE SINGLE TURNOVER CYCLE

  Hideyuki Kumita;Koji Matsuura;Tomoya Hino;Satoshi Takahashi

  128
  Citations

• Roles of the proximal hydrogen bonding network in cytochrome P450cam-catalyzed oxygenation.

  Shiro Yoshioka;Takehiko Tosha;Satoshi Takahashi;Koichiro Ishimori

  127
  Citations

• On the mechanism of the chemical and enzymic oxygenations of alpha-oxyprotohemin IX to Fe.biliverdin IX alpha

  Seiyo Sano;Toyo Sano;Isao Morishima;Yoshitugu Shiro

  127
  Citations

• Calcium binding by horseradish peroxidase c and the heme environmental structure

  Satoshi Ogawa;Yoshitsugu Shiro;Isao Morishima

  126
  Citations

• Presence of endogenous calcium ion in horseradish peroxidase. Elucidation of metal-binding site by substitutions of divalent and lanthanide ions for calcium and use of metal-induced NMR (1H and 113Cd) resonances.

  I Morishima;M Kurono;Y Shiro

  119
  Citations

• Catalytic Roles of the Distal Site Asparagine−Histidine Couple in Peroxidases†

  Shingo Nagano;Motomasa Tanaka;Koichiro Ishimori;Yoshihito Watanabe

  119
  Citations

• Alteration of human myoglobin proximal histidine to cysteine or tyrosine by site-directed mutagenesis: characterization and their catalytic activities.

  Shin-ichi Adachi;Shingo Nagano;Yoshihito Watanabe;Koichiro Ishimori

  106
  Citations