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Genetics

D-Index
48
Citations
13261
World Ranking
4033
National Ranking
1741

Overview

Margarete Mehrabian is affiliated with the University of California, Los Angeles in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions in Molecular Biology, Physiology, Epidemiology, Health, Toxicology and Mutagenesis, and Immunology.

Their work focuses on several main topics including:

  • Gut microbiota and health
  • Gout, Hyperuricemia, Uric Acid
  • Liver Disease Diagnosis and Treatment
  • Atherosclerosis and Cardiovascular Diseases
  • Diet and metabolism studies
  • Tryptophan and brain disorders
  • Dietary Effects on Health

Recent publications by Margarete Mehrabian include:

  • "Genome-wide analysis identifies novel susceptibility loci for myocardial infarction" (2020) in European Heart Journal
  • "Gut bacterial metabolism contributes to host global purine homeostasis" (2023) in Cell Host & Microbe
  • "Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis" (2020) in Arteriosclerosis Thrombosis and Vascular Biology
  • "Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk" (2020) in UNC Libraries
  • "Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms" (2022) in eLife

The scientist has frequently published in venues such as UNC Libraries, Arteriosclerosis Thrombosis and Vascular Biology, bioRxiv (Cold Spring Harbor Laboratory), European Heart Journal, and Cell Host & Microbe.

Margarete Mehrabian has collaborated extensively with several co-authors including:

  • Aldons J. Lusis
  • Mete Civelek
  • Stanley L. Hazen
  • Brian W. Parks
  • Marcus Seldin

Best Publications

  • Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.

    Weifei Zhu;Jill C. Gregory;Elin Org;Jennifer A. Buffa

  • Mapping the Genetic Architecture of Gene Expression in Human Liver

    Eric E. Schadt;Cliona Molony;Eugene Chudin;Ke-Ke Hao

  • Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis.

    James H. Dwyer;Hooman Allayee;Kathleen M. Dwyer;Jing Fan

  • Sex differences and hormonal effects on gut microbiota composition in mice

    Elin Org;Margarete Mehrabian;Brian W. Parks;Petia Shipkova

  • Genetic Control of Obesity and Gut Microbiota Composition in Response to High-Fat, High-Sucrose Diet in Mice

    Brian W. Parks;Elizabeth Nam;Elin Org;Emrah Kostem

  • The nature and identification of quantitative trait loci: a community's view.

    Oduola Abiola;Joe M. Angel;Philip Avner;Alexander A. Bachmanov

  • Identification of 5-Lipoxygenase as a Major Gene Contributing to Atherosclerosis Susceptibility in Mice

    Margarete Mehrabian;Hooman Allayee;Jack Wong;Weibin Shih

  • Interactions between Roseburia intestinalis and diet modulate atherogenesis in a murine model

    Kazuyuki Kasahara;Kimberly A. Krautkramer;Elin Org;Kymberleigh A. Romano

  • Genetic and environmental control of host-gut microbiota interactions

    Elin Org;Brian W W Parks;Jong Wha J Joo;Benjamin Emert

  • Role of Group II Secretory Phospholipase A2 in Atherosclerosis : 1. Increased Atherogenesis and Altered Lipoproteins in Transgenic Mice Expressing Group IIa Phospholipase A2

    Boris Ivandic;Lawrence W. Castellani;Xu-Ping Wang;Jian-Hua Qiao

  • Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.

    Xia Yang;Joshua L Deignan;Hongxiu Qi;Jun Zhu

  • Minimally modified low density lipoprotein is biologically active in vivo in mice.

    Feng Liao;Judith A. Berliner;Margarete Mehrabian;Mahamad Navab

  • Relationships between gut microbiota, plasma metabolites, and metabolic syndrome traits in the METSIM cohort

    Elin Org;Elin Org;Yuna Blum;Silva Kasela;Margarete Mehrabian

  • Genetic Architecture of Insulin Resistance in the Mouse

    Brian W. Parks;Tamer Sallam;Margarete Mehrabian;Nikolas Psychogios

  • Integrating genotypic and expression data in a segregating mouse population to identify 5-lipoxygenase as a susceptibility gene for obesity and bone traits

    Margarete Mehrabian;Hooman Allayee;Jirina Stockton;Pek Yee Lum

  • Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.

    M Mehrabian;P Z Wen;J Fisler;R C Davis

  • Genome-wide analysis identifies novel susceptibility loci for myocardial infarction

    Jaana A Hartiala;Yi Han;Qiong Jia;James R Hilser

  • Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11-q12

    Jonathan C. Cohen;James J. Cali;Diane F. Jelinek;Margarete Mehrabian

  • 5-lipoxygenase and atherosclerosis.

    Margarete Mehrabian;Hooman Allayee

  • The Hybrid Mouse Diversity Panel: A Resource for Systems Genetics Analyses of Metabolic and Cardiovascular Traits

    Aldons J. Lusis;Marcus M. Seldin;Hooman Allayee;Brian J. Bennett

Frequent Co-Authors

Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles
Hooman Allayee
Hooman Allayee University of Southern California
Thomas A. Drake
Thomas A. Drake University of California, Los Angeles
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai
Alan M. Fogelman
Alan M. Fogelman University of California, Los Angeles
Stanley L. Hazen
Stanley L. Hazen Cleveland Clinic Lerner College of Medicine
Charles R. Farber
Charles R. Farber University of Virginia
Robert S. Sparkes
Robert S. Sparkes University of California, Los Angeles
Laurent Vergnes
Laurent Vergnes University of California, Los Angeles
Karen Reue
Karen Reue University of California, Los Angeles

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