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D-Index & Metrics

Genetics

D-Index
61
Citations
15350
World Ranking
3050
National Ranking
1332

Overview

Xia Yang is affiliated with the University of California, Los Angeles in the United States. Their primary fields of study include Medicine and Biochemistry, Genetics and Molecular Biology, with substantial contributions to subfields such as Molecular Biology, Physiology, Epidemiology, Neurology, and Genetics.

The scientist's research spans several main topics, including:

  • Single-cell and spatial transcriptomics
  • Adipose Tissue and Metabolism
  • Bioinformatics and Genomic Networks
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Diet, Metabolism, and Disease
  • Liver Disease Diagnosis and Treatment
  • Diet and metabolism studies

Xia Yang has frequently published in venues such as bioRxiv (Cold Spring Harbor Laboratory), eLife, Circulation, Research Square, and Cell Reports. These outlets reflect a focus on cutting-edge biomedical and genomic research platforms.

Their recent papers include:

  • Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes, 2021, Nature Communications
  • Joint cell segmentation and cell type annotation for spatial transcriptomics, 2021, Molecular Systems Biology
  • Hypothalamic oestrogen receptor alpha establishes a sexually dimorphic regulatory node of energy expenditure, 2020, Nature Metabolism
  • Single-cell RNA-seq analysis of the brainstem of mutant SOD1 mice reveals perturbed cell types and pathways of amyotrophic lateral sclerosis, 2020, Neurobiology of Disease
  • Mergeomics 2.0: a web server for multi-omics data integration to elucidate disease networks and predict therapeutics, 2021, Nucleic Acids Research

Xia Yang collaborates regularly with several researchers, including:

  • Graciel Diamante
  • In Sook Ahn
  • Montgomery Blencowe
  • Ingrid Cely
  • Aldons J. Lusis

Best Publications

  • An integrative genomics approach to infer causal associations between gene expression and disease

    Eric E Schadt;John Lamb;Xia Yang;Jun Zhu

  • Mapping the Genetic Architecture of Gene Expression in Human Liver

    Eric E. Schadt;Cliona Molony;Eugene Chudin;Ke-Ke Hao

  • Variations in DNA elucidate molecular networks that cause disease

    Yanqing Chen;Jun Zhu;Pek Yee Lum;Xia Yang

  • Tissue-specific expression and regulation of sexually dimorphic genes in mice

    Xia Yang;Eric E. Schadt;Susanna Wang;Hui Wang

  • Relationship of Paraoxonase 1 (PON1) Gene Polymorphisms and Functional Activity With Systemic Oxidative Stress and Cardiovascular Risk

    Tamali Bhattacharyya;Stephen J. Nicholls;Eric J. Topol;Renliang Zhang

  • Co-regulatory networks of human serum proteins link genetics to disease

    Valur Emilsson;Marjan Ilkov;John R. Lamb;Nancy Finkel

  • Dosage compensation is less effective in birds than in mammals.

    Yuichiro Itoh;Esther Melamed;Xia Yang;Kathy Kampf

  • Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity

    Antigone S Dimas;Vasiliki Lagou;Adam Barker;Joshua W Knowles

  • Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks.

    Xia Yang;Joshua L Deignan;Hongxiu Qi;Jun Zhu

  • Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver

    Xia Yang;Bin Zhang;Cliona Molony;Eugene Chudin

  • Integrating Pathway Analysis and Genetics of Gene Expression for Genome-wide Association Studies

    Hua Zhong;Xia Yang;Lee M. Kaplan;Cliona Molony

  • Extended Multiplexing of Tandem Mass Tags (TMT) Labeling Reveals Age and High Fat Diet Specific Proteome Changes in Mouse Epididymal Adipose Tissue.

    Deanna L. Plubell;Phillip A. Wilmarth;Yuqi Zhao;Alexandra M. Fenton

  • Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS.

    Xin He;Chris K. Fuller;Yi Song;Qingying Meng

  • Targeting BCAA Catabolism to Treat Obesity-Associated Insulin Resistance.

    Meiyi Zhou;Jing Shao;Cheng Yang Wu;Le Shu

  • Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.

    Ville-Petteri Mäkinen;Mete Civelek;Qingying Meng;Bin Zhang

  • Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

    Manikandan Narayanan;Jimmy L Huynh;Kai Wang;Xia Yang

  • Liver and Adipose Expression Associated SNPs Are Enriched for Association to Type 2 Diabetes

    Hua Zhong;John Beaulaurier;Pek Yee Lum;Cliona Molony

  • Applications and Limitations of Mouse Models for Understanding Human Atherosclerosis

    Moritz von Scheidt;Yuqi Zhao;Zeyneb Kurt;Calvin Pan

  • A Systems Biology Framework Identifies Molecular Underpinnings of Coronary Heart Disease

    Tianxiao Huan;Bin Zhang;Zhi Wang;Roby Joehanes

  • Impact of Type 2 Diabetes Susceptibility Variants on Quantitative Glycemic Traits Reveals Mechanistic Heterogeneity

    Antigone S. Dimas;Vasiliki Lagou;Adam Barker;Joshua W. Knowles

Frequent Co-Authors

Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles
Bin Zhang
Bin Zhang Icahn School of Medicine at Mount Sinai
Jun Zhu
Jun Zhu Icahn School of Medicine at Mount Sinai
Eric E. Schadt
Eric E. Schadt Icahn School of Medicine at Mount Sinai
Fernando Gomez-Pinilla
Fernando Gomez-Pinilla University of California, Los Angeles
Zhe Ying
Zhe Ying University of California, Los Angeles
Themistocles L. Assimes
Themistocles L. Assimes Stanford University
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Thomas Quertermous
Thomas Quertermous Stanford University
Ke Hao
Ke Hao Icahn School of Medicine at Mount Sinai

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