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Leo-Pekka Lyytikäinen

Leo-Pekka Lyytikäinen

D-Index & Metrics

Medicine

D-Index
79
Citations
26009
World Ranking
17457
National Ranking
197

Overview

Leo-Pekka Lyytikäinen is affiliated with Tampere University Hospital in Finland and has contributed extensively to research in medicine, with a focus also on biochemistry, genetics, and molecular biology. Their research spans multiple interconnected fields, reflecting a multidisciplinary approach within biomedical sciences.

The main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, their work concentrates on several subfields such as:

  • Cardiology and Cardiovascular Medicine
  • Genetics
  • Molecular Biology
  • Physiology
  • Pediatrics, Perinatology and Child Health

Key research topics covered by Leo-Pekka Lyytikäinen include:

  • Genetic Associations and Epidemiology
  • Cardiac electrophysiology and arrhythmias
  • Birth, Development, and Health
  • Cardiac Arrhythmias and Treatments
  • Blood groups and transfusion
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer

The scientist has contributed to several recent publications, including:

  • The Polygenic and Monogenic Basis of Blood Traits and Diseases, 2020, Cell
  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations, 2020, Cell
  • Genome-wide analysis identifies novel susceptibility loci for myocardial infarction, 2020, European Heart Journal
  • Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention, 2022, Nature Genetics
  • Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification, 2023, Nature Genetics

Frequent co-authors who have collaborated with Leo-Pekka Lyytikäinen include:

  • Terho Lehtimäki
  • Mika Kähönen
  • Olli T. Raitakari
  • Kjell Nikus
  • Nina Mononen

Work is regularly published in a range of venues such as:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Molecular Psychiatry
  • Atherosclerosis

Best Publications

  • Discovery and refinement of loci associated with lipid levels

    Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta;Gina M. Peloso;Gina M. Peloso;Gina M. Peloso

  • Large-scale association analysis identifies new risk loci for coronary artery disease

    Panos Deloukas;Stavroula Kanoni;Christina Willenborg;Martin Farrall

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.

    Evangelos Evangelou;Evangelos Evangelou;Helen R. Warren;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsud

  • Common variants associated with plasma triglycerides and risk for coronary artery disease

    Ron Do;Cristen J. Willer;Ellen M. Schmidt;Sebanti Sengupta

  • Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

    Johannes Kettunen;Ayşe Demirkan;Ayşe Demirkan;Peter Würtz;Harmen H M Draisma

  • Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation

    Carolina Roselli;Mark D. Chaffin;Lu Chen Weng;Lu Chen Weng;Stefanie Aeschbacher

  • Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function

    Gail Davies;Max Lam;Sarah E. Harris;Joey W. Trampush

  • Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors

    Ari V. Ahola-Olli;Peter Würtz;Aki S. Havulinna;Kristiina Aalto

  • Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.

    Ming-Huei Chen;Laura M Raffield;Abdou Mousas;Saori Sakaue

  • Genome-wide association study identifies multiple loci influencing human serum metabolite levels

    Johannes Kettunen;Johannes Kettunen;Taru Tukiainen;Antti-Pekka Sarin;Antti-Pekka Sarin;Alfredo Ortega-Alonso

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits: A Multi-Ethnic Meta-Analysis of 45,891 Individuals

    Z Dastani;Hivert M-F.;Hivert M-F.;N Timpson;Perry Jrb.;Perry Jrb.

  • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk

    Helen R Warren;Evangelos Evangelou;Evangelos Evangelou;Claudia P Cabrera;He Gao

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

    Emma Raitoharju;Leo-Pekka Lyytikäinen;Mari Levula;Niku Oksala

  • The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

    Georg B. Ehret;Georg B. Ehret;Teresa Ferreira;Daniel I. Chasman;Anne U. Jackson

  • Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

    Valérie Turcot;Yingchang Lu;Yingchang Lu;Heather M Highland;Heather M Highland;Claudia Schurmann

  • Genome-wide Association Study in 79,366 European-ancestry Individuals Informs the Genetic Architecture of 25-Hydroxyvitamin D Levels

    Xia Jiang;Xia Jiang;Paul F. O'Reilly;Hugues Aschard;Hugues Aschard;Yi Hsiang Hsu;Yi Hsiang Hsu

  • The Polygenic and Monogenic Basis of Blood Traits and Diseases

    Dragana Vuckovic;Dragana Vuckovic;Erik L. Bao;Erik L. Bao;Parsa Akbari;Caleb A. Lareau;Caleb A. Lareau

  • Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

    Evangelos Evangelou;Helen R. Warren;David Mosen-Ansorena;Borbala Mifsu

Frequent Co-Authors

Olli T. Raitakari
Olli T. Raitakari Turku University Hospital
Terho Lehtimäki
Terho Lehtimäki Tampere University
Mika Kähönen
Mika Kähönen Tampere University
André G. Uitterlinden
André G. Uitterlinden Erasmus University Rotterdam
Bruce M. Psaty
Bruce M. Psaty University of Washington
Nilesh J. Samani
Nilesh J. Samani University of Leicester
Christopher P. Nelson
Christopher P. Nelson University of Leicester
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Eric Boerwinkle
Eric Boerwinkle The University of Texas Health Science Center at Houston
Andrew P. Morris
Andrew P. Morris University of Liverpool

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