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Immunology

D-Index
76
Citations
22813
World Ranking
1900
National Ranking
925

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

David J. Erle is affiliated with the University of California, San Francisco in the United States. Their research primarily focuses on the field of Medicine, with significant contributions to Infectious Diseases, Immunology, Pulmonary and Respiratory Medicine, Neurology, and Molecular Biology.

The scientist's research covers several main topics, including:

  • COVID-19 Clinical Research Studies
  • Long-Term Effects of COVID-19
  • SARS-CoV-2 and COVID-19 Research
  • Neonatal Respiratory Health Research
  • Asthma and respiratory diseases
  • Respiratory Support and Mechanisms
  • Respiratory viral infections research

Notable recent publications by David J. Erle include:

  • Global absence and targeting of protective immune states in severe COVID-19, 2021, Nature
  • Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men, 2020, Cell Stem Cell
  • Type I interferon autoantibodies are associated with systemic immune alterations in patients with COVID-19, 2021, Science Translational Medicine
  • Discovering dominant tumor immune archetypes in a pan-cancer census, 2021, Cell
  • Increased risk of severe clinical course of COVID-19 in carriers of HLA-C*04:01, 2021, EClinicalMedicine

Frequent co-authors collaborating with David J. Erle include:

  • Carolyn S. Calfee
  • Charles Langelier
  • Prescott G. Woodruff
  • Matthew F. Krummel
  • Walter L. Eckalbar

Their work has been published in multiple venues, with a concentration in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Respiratory and Critical Care Medicine
  • Nature Communications
  • JCI Insight
  • American Journal of Respiratory Cell and Molecular Biology

David J. Erle is recognized as a Member of the Association of American Physicians.

Best Publications

  • Systemically dispersed innate IL-13-expressing cells in type 2 immunity.

    April E. Price;Hong-Erh Liang;Brandon M. Sullivan;R. Lee Reinhardt

  • Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

    Miranda L. Broz;Mikhail Binnewies;Bijan Boldajipour;Amanda E. Nelson

  • Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma

    Douglas A. Kuperman;Xiaozhu Huang;Laura L. Koth;Grace H. Chang

  • Genome-wide profiling identifies epithelial cell genes associated with asthma and with treatment response to corticosteroids

    Prescott G. Woodruff;Homer A. Boushey;Gregory M. Dolganov;Chris S. Barker

  • Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

    David B. Corry;Hans G. Folkesson;Martha L. Warnock;David J. Erle

  • Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.

    Unknown

  • Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit.

    Marija S. Nadjsombati;John W. McGinty;Miranda R. Lyons-Cohen;James B. Jaffe

  • Expression and function of the MAdCAM-1 receptor, integrin alpha 4 beta 7, on human leukocytes.

    D J Erle;M J Briskin;E C Butcher;A Garcia-Pardo

  • Role of integrin alpha 4 beta 7/alpha 4 beta P in lymphocyte adherence to fibronectin and VCAM-1 and in homotypic cell clustering

    C Rüegg;AA Postigo;EE Sikorski;EC Butcher

  • Tissue signals imprint ILC2 identity with anticipatory function.

    Roberto R. Ricardo-Gonzalez;Steven J. Van Dyken;Steven J. Van Dyken;Christoph Schneider;Jinwoo Lee

  • Inactivation of the integrin beta 6 subunit gene reveals a role of epithelial integrins in regulating inflammation in the lung and skin.

    X Z Huang;J F Wu;D Cass;D J Erle

  • Airway Mucus and Asthma: The Role of MUC5AC and MUC5B.

    Luke R. Bonser;David J. Erle

  • Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients

    Bettina Levänen;Nirav R. Bhakta;Patricia Torregrosa Paredes;Rebecca Barbeau

  • The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells.

    Rajeev Venkayya;Maggie Lam;Madeleine Willkom;Gabriele Grünig

  • The cell biology of asthma

    David J. Erle;Dean Sheppard

  • Selective expression of integrin alpha 4 beta 7 on a subset of human CD4+ memory T cells with Hallmarks of gut-trophism.

    T. Schweighoffer;Y. Tanaka;M. Tidswell;D. J. Erle

  • IL-13 and epidermal growth factor receptor have critical but distinct roles in epithelial cell mucin production.

    Guohua Zhen;Sung Woo Park;Louis T. Nguyenvu;Madeleine W. Rodriguez

  • Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development

    Corey N. Miller;Irina Proekt;Jakob von Moltke;Kristen L. Wells

  • Dissecting asthma using focused transgenic modeling and functional genomics

    Douglas A. Kuperman;Christina C. Lewis;Prescott G. Woodruff;Madeleine W. Rodriguez

  • Airway Epithelial miRNA Expression Is Altered in Asthma

    Owen D. Solberg;Edwin Justin Ostrin;Michael I. Love;Jeffrey C. Peng

  • Global absence and targeting of protective immune states in severe COVID-19.

    Alexis J. Combes;Tristan Courau;Nicholas F. Kuhn;Kenneth H. Hu

  • Interleukin-13 Induces Dramatically Different Transcriptional Programs in Three Human Airway Cell Types

    June H. Lee;Naftali Kaminski;Gregory Dolganov;Gabriele Grunig

  • Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

    D Sheppard;C Rozzo;L Starr;V Quaranta

Frequent Co-Authors

Prescott G. Woodruff
Prescott G. Woodruff University of California, San Francisco
Walter E. Finkbeiner
Walter E. Finkbeiner University of California, San Francisco
Dean Sheppard
Dean Sheppard University of California, San Francisco
Xiaozhu Huang
Xiaozhu Huang University of California, San Francisco
Matthew F. Krummel
Matthew F. Krummel University of California, San Francisco
Michael A. Matthay
Michael A. Matthay University of California, San Francisco
Carolyn S. Calfee
Carolyn S. Calfee University of California, San Francisco
Louise C. Laurent
Louise C. Laurent University of California, San Diego
Richard M. Locksley
Richard M. Locksley University of California, San Francisco
K. Mark Ansel
K. Mark Ansel University of California, San Francisco

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