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Margaret James Koziel

Margaret James Koziel

D-Index & Metrics

Immunology

D-Index
46
Citations
11066
World Ranking
4585
National Ranking
2065

Overview

Margaret James Koziel is affiliated with Harvard Medical School in the United States and has a research focus primarily within the field of medicine. Their scholarly output includes work in several subfields such as epidemiology, neurology, hepatology, genetics, and physiology. The scope of their research covers multiple topics, notably liver disease diagnosis and treatment, long-term effects of COVID-19, hepatitis C virus research, hemoglobinopathies and related disorders, erythrocyte function and pathophysiology, iron metabolism and disorders, and hepatitis B virus studies.

Among the frequent publication venues for Koziel's work are:

  • Journal of Hepatology
  • Gastroenterology
  • EClinicalMedicine
  • The American Journal of Gastroenterology
  • Medical Research Archives

Koziel collaborates regularly with several coauthors, including Karim Azer, Stephen A. Harrison, Seth J. Baum, Nadege Gunn, and Ziad Younes.

Their recent papers include:

  • "Efficacy and tolerability of an endogenous metabolic modulator (AXA1125) in fatigue-predominant long COVID: a single-centre, double-blind, randomised controlled phase 2a pilot study," 2023, published in EClinicalMedicine
  • "Safety, Tolerability, and Biologic Activity of AXA1125 and AXA1957 in Subjects With Nonalcoholic Fatty Liver Disease," 2021, published in The American Journal of Gastroenterology
  • "Multifactorial effects of AXA1125 and AXA1957 observed on markers of metabolism, inflammation and fibrosis: a 16-week randomized placebo-controlled study in subjects with non-alcoholic fatty liver disease (NAFLD) with and without type 2 diabetes (T2D)," 2020, published in Journal of Hepatology
  • "723: ONCE-MONTHLY EFIMOSFERMIN ALFA (BOS-580) IN METABOLIC DYSFUNCTION-ASSOCIATED STEATOHEPATITIS WITH F2/F3 FIBROSIS: RESULTS FROM A 24 WEEK, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, PHASE 2 TRIAL," 2025, published in Gastroenterology
  • "Insights Into Long COVID Fatigue Biology: Potential Treatment Implications Using Multi-Targeted Action of AXA1125, a Novel Endogenous Metabolic Modulator Composition," 2024, published in Medical Research Archives

Best Publications

  • Influence of Human Immunodeficiency Virus Infection on the Course of Hepatitis C Virus Infection: A Meta-Analysis

    C. S. Graham;L. R. Baden;E. Yu;J. M. Mrus

  • Peginterferon Alfa-2a plus ribavirin versus interferon alfa-2a plus ribavirin for chronic hepatitis C in HIV-coinfected persons.

    Raymond T. Chung;Janet Andersen;Paul Volberding;Gregory K. Robbins

  • Intrahepatic cytotoxic T lymphocytes specific for hepatitis C virus in persons with chronic hepatitis.

    M J Koziel;D Dudley;J T Wong;J Dienstag

  • Viral Hepatitis in HIV Infection

    Margaret James Koziel;Marion G. Peters

  • HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.

    M J Koziel;D Dudley;N Afdhal;A Grakoui

  • Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV.

    M. J. Koziel;D. Dudley;N. Afdhal;Qui-Lim Choo

  • Cytokines in viral hepatitis.

    Margaret James Koziel

  • PULMONARY COMPLICATIONS OF DIABETES MELLITUS: Pneumonia

    Henry Koziel;Margaret James Koziel

  • Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes.

    O O Yang;S A Kalams;M Rosenzweig;A Trocha

  • Peginterferon Alfa-2b Therapy in Acute Hepatitis C: Impact of Onset of Therapy on Sustained Virologic Response

    Sanaa M. Kamal;Sanaa M. Kamal;Sanaa M. Kamal;Amr E. Fouly;Refaat R. Kamel;Bridgette Hockenjos

  • Pegylated interferon α therapy in acute hepatitis C: Relation to hepatitis C virus–specific T cell response kinetics

    Sanaa M. Kamal;Sanaa M. Kamal;Alaa Ismail;Camilla S. Graham;Qi He

  • Liver-Derived CTL in Hepatitis C Virus Infection: Breadth and Specificity of Responses in a Cohort of Persons with Chronic Infection

    David K. H. Wong;Darryll D. Dudley;Nezam H. Afdhal;Jules Dienstag

  • The role of immune responses in the pathogenesis of hepatitis C virus infection

    M. J. Koziel

  • To be or not to be NKT: natural killer T cells in the liver.

    Mark A. Exley;Margaret James Koziel

  • Impact of Hepatitis C Virus on Immune Restoration in HIV-Infected Patients Who Start Highly Active Antiretroviral Therapy: A Meta-analysis

    Melissa Farmer Miller;Clinton Haley;Margaret James Koziel;Christopher F. Rowley

  • Association of multispecific CD4+ response to hepatitis C and severity of recurrence after liver transplantation

    Hugo R. Rosen;David J. Hinrichs;David R. Gretch;Margaret J. Koziel

  • Hepatitis C Virus-Specific Cytolytic T Lymphocyte and T Helper Cell Responses in Seronegative Persons

    Margaret James Koziel;David K. H. Wong;Darryll Dudley;Michael Houghton

  • Acute hepatitis C without and with schistosomiasis: Correlation with hepatitis C–Specific CD4+ T-cell and cytokine response☆☆☆

    Sanaa M. Kamal;Sanaa M. Kamal;Jens W. Rasenack;Leonardo Bianchi;Ahmed Al Tawil

  • Cutting edge: Compartmentalization of Th1-like noninvariant CD1d-reactive T cells in hepatitis C virus-infected liver.

    Mark A. Exley;Qi He;Olivia Cheng;Ruo Jie Wang

  • Transgenic expression of hepatitis C virus structural proteins in the mouse

    T Kawamura;A Furusaka;M J Koziel;R T Chung

Frequent Co-Authors

Kenneth E. Sherman
Kenneth E. Sherman University of Cincinnati Medical Center
Marion G. Peters
Marion G. Peters University of California, San Francisco
Raymond T. Chung
Raymond T. Chung Harvard University
Nezam H. Afdhal
Nezam H. Afdhal Beth Israel Deaconess Medical Center
Bruce D. Walker
Bruce D. Walker Harvard University
Mark A. Exley
Mark A. Exley Brigham and Women's Hospital
Michael Houghton
Michael Houghton University of Alberta
T. Jake Liang
T. Jake Liang National Institutes of Health
Timothy Heeren
Timothy Heeren Boston University
Donald E. Craven
Donald E. Craven Tufts University

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