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Immunology

D-Index
58
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15030
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3491
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1621

Overview

Otto O. Yang is affiliated with the University of California, Los Angeles in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on several subfields including Infectious Diseases, Immunology, Neurology, Epidemiology, and Molecular Biology.

The main topics in their work include SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Long-Term Effects of COVID-19, Immune Cell Function and Interaction, HIV Research and Treatment, SARS-CoV-2 detection and testing, and CAR-T cell therapy research.

Otto O. Yang has authored several recent papers notable for their contributions to understanding COVID-19 and immune responses. These include:

  • Rapid Decay of Anti-SARS-CoV-2 Antibodies in Persons with Mild Covid-19 (2020), published in New England Journal of Medicine
  • Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial (2022), published in The Lancet Respiratory Medicine
  • Primary, Recall, and Decay Kinetics of SARS-CoV-2 Vaccine Antibody Responses (2021), published in ACS Nano
  • Abatacept, Cenicriviroc, or Infliximab for Treatment of Adults Hospitalized With COVID-19 Pneumonia (2023), published in JAMA
  • The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2 (2021), published in Cell Reports Medicine

Their frequent coauthors include:

  • F. Javier Ibarrondo
  • Jennifer A. Fulcher
  • Grace M. Aldrovandi
  • Nicole H. Tobin
  • Kathie G. Ferbas

Otto O. Yang's research has been published predominantly in the following venues:

  • Clinical Infectious Diseases
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Infectious Diseases
  • New England Journal of Medicine

Best Publications

  • The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

    Pereyra F;Jia X;McLaren Pj

  • Rapid Decay of Anti–SARS-CoV-2 Antibodies in Persons with Mild Covid-19

    F. Javier Ibarrondo;Jennifer A. Fulcher;David Goodman-Meza;Julie Elliott

  • Hydrodynamic stretching of single cells for large population mechanical phenotyping

    Daniel R. Gossett;Henry T. K. Tse;Serena A. Lee;Yong Ying

  • Retrocyclin: A primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1

    Alexander M. Cole;Teresa Hong;Lee Ming Boo;Tung Nguyen

  • Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans.

    Ludwig Wagner;Otto O. Yang;Eduardo A. Garcia-Zepeda;Yimin Ge

  • Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms.

    O O Yang;S A Kalams;A Trocha;H Cao

  • Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression.

    Jonah B. Sacha;Chungwon Chung;Eva G. Rakasz;Sean P. Spencer

  • Good's syndrome remains a mystery after 55 years: A systematic review of the scientific evidence.

    Theodoros Kelesidis;Otto Yang

  • Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes.

    O O Yang;S A Kalams;M Rosenzweig;A Trocha

  • Gene therapy for adenosine deaminase–deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans

    Fabio Candotti;Kit L. Shaw;Linda Muul;Denise Carbonaro

  • Biomarkers of Microbial Translocation and Macrophage Activation: Association With Progression of Subclinical Atherosclerosis in HIV-1 Infection

    Theodoros Kelesidis;Michelle A. Kendall;Otto O. Yang;Howard N. Hodis

  • Telomerase-Based Pharmacologic Enhancement of Antiviral Function of Human CD8+ T Lymphocytes

    Steven Russell Fauce;Beth D. Jamieson;Allison C. Chin;Ronald T. Mitsuyasu

  • The θ-Defensin, Retrocyclin, Inhibits HIV-1 Entry

    Carsten Münk;Ge Wei;Otto O. Yang;Alan J. Waring

  • Definition of the viral targets of protective HIV-1-specific T cell responses.

    Beatriz Mothe;Anuska Llano;F. Javier Ibarrondo;Marcus Daniels

  • A highly efficient short hairpin RNA potently down-regulates CCR5 expression in systemic lymphoid organs in the hu-BLT mouse model

    Saki Shimizu;Patrick Hong;Balamurugan Arumugam;Lauren Pokomo

  • Lysis of HIV-1-infected cells and inhibition of viral replication by universal receptor T cells

    O O Yang;A C Tran;S A Kalams;R P Johnson

  • Determinants of HIV-1 Mutational Escape From Cytotoxic T Lymphocytes

    Otto O. Yang;Phuong Thi Nguyen Sarkis;Ayub Ali;Jason D. Harlow

  • Nef-Mediated Resistance of Human Immunodeficiency Virus Type 1 to Antiviral Cytotoxic T Lymphocytes

    Otto O. Yang;Phuong Thi Nguyen;Spyros A. Kalams;Tanya Dorfman

  • HIV-specific Immunity Derived From Chimeric Antigen Receptor-engineered Stem Cells.

    Anjie Zhen;Masakazu Kamata;Valerie Rezek;Jonathan Rick

  • Changes in Bone Mineral Density After Initiation of Antiretroviral Treatment With Tenofovir Disoproxil Fumarate/Emtricitabine Plus Atazanavir/Ritonavir, Darunavir/Ritonavir, or Raltegravir

    Todd T. Brown;Carlee Moser;Judith S. Currier;Heather J. Ribaudo

  • CD8+ cells in human immunodeficiency virus type I pathogenesis: cytolytic and noncytolytic inhibition of viral replication.

    Otto O. Yang;Bruce D. Walker

Frequent Co-Authors

Beth D. Jamieson
Beth D. Jamieson University of California, Los Angeles
Judith S. Currier
Judith S. Currier University of California, Los Angeles
Bruce D. Walker
Bruce D. Walker Harvard University
Peter A. Anton
Peter A. Anton University of California, Los Angeles
Irvin S. Y. Chen
Irvin S. Y. Chen University of California, Los Angeles
Spyros A. Kalams
Spyros A. Kalams Vanderbilt University Medical Center
Jerome A. Zack
Jerome A. Zack University of California, Los Angeles
Grace A. McComsey
Grace A. McComsey Case Western Reserve University
Alicja Trocha
Alicja Trocha Ragon Institute of MGH, MIT and Harvard
Eric S. Daar
Eric S. Daar Lundquist Institute

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