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Immunology

D-Index
66
Citations
19515
World Ranking
2730
National Ranking
1301

Overview

Spyros A. Kalams is affiliated with Vanderbilt University Medical Center in the United States and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research spans several subfields, including Immunology, Epidemiology, Infectious Diseases, Virology, and Emergency Medicine.

The scientist's research covers a range of main topics, with a notable focus on HIV research and treatment. Additional principal areas include immune cell function and interaction, HIV-related health complications and treatments, influenza virus research studies, SARS-CoV-2 and COVID-19 research, adipokines, inflammation, and metabolic diseases, as well as respiratory viral infections research.

Kalams has coauthored works frequently with several researchers, including S. Mallal, Samuel Bailin, Celestine N. Wanjalla, Joshua D. Simmons, and Mona Mashayekhi.

Their recent contributions to scientific literature include:

  • Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial, 2022, Science
  • Immune Correlates Analysis of the mRNA-1273 COVID-19 Vaccine Efficacy Trial, 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • Robust antibody and cellular responses induced by DNA-only vaccination for HIV, 2020, JCI Insight
  • Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells, 2021, Cell Reports Medicine
  • Humoral and cellular immune responses to the SARS-CoV-2 BNT162b2 vaccine among a cohort of solid organ transplant recipients and healthy controls, 2021, Transplant Infectious Disease

Kalams' research has appeared frequently in specific publication venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Frontiers in Immunology
  • SSRN Electronic Journal
  • Journal of the Endocrine Society
  • Journal of Virology

Best Publications

  • Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

    Eric S. Rosenberg;James M. Billingsley;Angela M. Caliendo;Steven L. Boswell

  • HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes

    Kathleen L. Collins;Benjamin K. Chen;Spyros A. Kalams;Spyros A. Kalams;Bruce D. Walker;Bruce D. Walker

  • Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial.

    Peter B Gilbert;Peter B Gilbert;David C Montefiori;Adrian B McDermott;Youyi Fong

  • The Critical Need for CD4 Help in Maintaining Effective Cytotoxic T Lymphocyte Responses

    Spyros A. Kalams;Bruce D. Walker

  • Factors Associated with the Development of Cross-Reactive Neutralizing Antibodies during Human Immunodeficiency Virus Type 1 Infection

    D. Noah Sather;Jakob Armann;Jakob Armann;Lance K. Ching;Lance K. Ching;Angeliki Mavrantoni;Angeliki Mavrantoni

  • Cytotoxic T lymphocytes in asymptomatic long-term nonprogressing HIV-1 infection. Breadth and specificity of the response and relation to in vivo viral quasispecies in a person with prolonged infection and low viral load.

    T Harrer;E Harrer;S A Kalams;P Barbosa

  • Association between virus-specific cytotoxic T-lymphocyte and helper responses in human immunodeficiency virus type 1 infection.

    Spyros A. Kalams;S. P. Buchbinder;E. S. Rosenberg;J. M. Billingsley

  • Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy.

    Spyros A. Kalams;Philip J. Goulder;Amy K. Shea;Norman G. Jones

  • Beta-chemokines are released from HIV-1-specific cytolytic T-cell granules complexed to proteoglycans.

    Ludwig Wagner;Otto O. Yang;Eduardo A. Garcia-Zepeda;Yimin Ge

  • Strong Cytotoxic T Cell and Weak Neutralizing Antibody Responses in a Subset of Persons with Stable Nonprogressing HIV Type 1 Infection

    Thomas Harrer;Ellen Harrer;Spyros A. Kalams;Tarek Elbeik

  • Suppression of human immunodeficiency virus type 1 replication by CD8+ cells: evidence for HLA class I-restricted triggering of cytolytic and noncytolytic mechanisms.

    O O Yang;S A Kalams;A Trocha;H Cao

  • Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1

    Iliyana Mikell;D. Noah Sather;Spyros A. Kalams;Marcus Altfeld

  • DC-Dielectrophoretic separation of biological cells by size

    Yuejun Kang;Dongqing Li;Spyros A. Kalams;Josiane E. Eid

  • Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity

    Pedro O. Flores-Villanueva;Edmond J. Yunis;Julio C. Delgado;Eric Vittinghoff

  • Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection.

    Philip J.R. Goulder;Philip J.R. Goulder;Marcus A. Altfeld;Eric S. Rosenberg;Thi Nguyen

  • Immunological and Virological Analyses of Persons Infected by Human Immunodeficiency Virus Type 1 while Participating in Trials of Recombinant gp120 Subunit Vaccines

    R. I. Connor;B. T. M. Korber;B. S. Graham;B. H. Hahn

  • Efficient lysis of human immunodeficiency virus type 1-infected cells by cytotoxic T lymphocytes.

    O O Yang;S A Kalams;M Rosenzweig;A Trocha

  • Safety and Comparative Immunogenicity of an HIV-1 DNA Vaccine in Combination with Plasmid Interleukin 12 and Impact of Intramuscular Electroporation for Delivery

    Spyros A. Kalams;Scott D. Parker;Marnie Elizaga;Barbara Metch

  • Longitudinal analysis of T cell receptor (TCR) gene usage by human immunodeficiency virus 1 envelope-specific cytotoxic T lymphocyte clones reveals a limited TCR repertoire.

    S A Kalams;R P Johnson;A K Trocha;M J Dynan

  • Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape

    Dirk Meyer-Olson;Naglaa H. Shoukry;Kristen W. Brady;Helen Kim

Frequent Co-Authors

Bruce D. Walker
Bruce D. Walker Harvard University
Simon Mallal
Simon Mallal Vanderbilt University Medical Center
Alicja Trocha
Alicja Trocha Ragon Institute of MGH, MIT and Harvard
Silvana Gaudieri
Silvana Gaudieri University of Western Australia
Philip J. R. Goulder
Philip J. R. Goulder University of Oxford
Stephen C. De Rosa
Stephen C. De Rosa Fred Hutchinson Cancer Research Center
Susan Buchbinder
Susan Buchbinder University of California, San Francisco
Marcus Altfeld
Marcus Altfeld University Medical Center Hamburg-Eppendorf
Georgia D. Tomaras
Georgia D. Tomaras Duke University
Eric S. Rosenberg
Eric S. Rosenberg Harvard University

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