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Molecular Biology

D-Index
65
Citations
33594
World Ranking
1639
National Ranking
829

Overview

Louise C. Laurent is affiliated with the University of California, San Diego in the United States. Their research spans several interconnected fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Within these areas, their work concentrates on molecular biology, infectious diseases, obstetrics and gynecology, cancer research, and general health professions.

Their scholarly output covers a range of topics related to reproductive health and molecular mechanisms in disease. Main topics of their research include pregnancy and preeclampsia studies, microRNA in disease regulation, extracellular vesicles in disease, SARS-CoV-2 detection and testing, broader SARS-CoV-2 and COVID-19 research, the reproductive system and pregnancy, as well as biosensors and analytical detection.

Louise C. Laurent has published numerous papers with significant scientific venues featured in their body of work. Recent notable publications include:

  • RNA delivery by extracellular vesicles in mammalian cells and its applications, 2020, Nature Reviews Molecular Cell Biology
  • Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States, 2021, Cell
  • Exome Sequencing for Prenatal Diagnosis in Nonimmune Hydrops Fetalis, 2020, New England Journal of Medicine
  • Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce, 2021, New England Journal of Medicine
  • Glioma-Derived miRNA-Containing Extracellular Vesicles Induce Angiogenesis by Reprogramming Brain Endothelial Cells, 2020, Cell Reports

The venues where Louise C. Laurent frequently publishes include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Obstetrics and Gynecology
  • Placenta
  • SSRN Electronic Journal
  • iScience

Frequent collaborators in their research include Rob Knight, Mana M. Parast, Peter De Hoff, Abbas Hakim, and G Yeo. These coauthors reflect an interdisciplinary approach across molecular biology, infectious disease, and reproductive health domains.

The scope of Louise C. Laurent's work highlights a blend of clinical and molecular investigations with an emphasis on RNA biology, disease detection, and prenatal health. Their contributions to the understanding of extracellular vesicles and microRNA regulation intersect with their studies on infectious diseases including SARS-CoV-2, representing a diverse and multifaceted research portfolio.

Best Publications

  • Minimal information for studies of extracellular vesicles 2018 (MISEV2018) : a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines

    Clotilde Théry;Kenneth W. Witwer;Elena Aikawa;Maria Jose Alcaraz

  • Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells

    Daniel Ramsköld;Shujun Luo;Yu Chieh Wang;Robin Li

  • Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

    Mason A. Israel;Shauna H. Yuan;Cedric Bardy;Sol M. Reyna

  • RNA delivery by extracellular vesicles in mammalian cells and its applications.

    Killian P. O’Brien;Koen Breyne;Stefano Ughetto;Stefano Ughetto;Louise C. Laurent

  • Dynamic changes in the human methylome during differentiation

    Louise Laurent;Eleanor Wong;Guoliang Li;Tien Huynh

  • Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture.

    Louise C. Laurent;Louise C. Laurent;Igor Ulitsky;Igor Ulitsky;Ileana Slavin;Ha Tran

  • Cell-Free DNA Analysis for Noninvasive Examination of Trisomy

    Mary E. Norton;Bo Jacobsson;Geeta K. Swamy;Louise C. Laurent

  • Non-Invasive Chromosomal Evaluation (NICE) Study: results of a multicenter prospective cohort study for detection of fetal trisomy 21 and trisomy 18

    Mary E. Norton;Herb Brar;Jonathan Weiss;Ardeshir Karimi

  • Statistically based splicing detection reveals neural enrichment and tissue-specific induction of circular RNA during human fetal development

    Linda Szabo;Robert Morey;Nathan J. Palpant;Peter L. Wang

  • A bioinformatic assay for pluripotency in human cells

    Franz Josef Müller;Bernhard M. Schuldt;Roy Williams;Dylan Mason

  • Extracellular vesicles: roles in gamete maturation, fertilization and embryo implantation

    Ronit Machtinger;Louise C. Laurent;Andrea A. Baccarelli

  • Recurrent Variations in DNA Methylation in Human Pluripotent Stem Cells and Their Differentiated Derivatives

    Kristopher L. Nazor;Gulsah Altun;Candace Lynch;Ha Tran

  • Regulatory networks define phenotypic classes of human stem cell lines

    Franz-Josef Müller;Franz-Josef Müller;Louise C. Laurent;Louise C. Laurent;Dennis Kostka;Igor Ulitsky

  • Abnormalities in human pluripotent cells due to reprogramming mechanisms

    Hong Ma;Robert Morey;Ryan C. O'Neil;Ryan C. O'Neil;Yupeng He;Yupeng He

  • Emergence and rapid transmission of SARS-CoV-2 B.1.1.7 in the United States.

    Nicole L. Washington;Karthik Gangavarapu;Mark Zeller;Alexandre Bolze

  • Molecular resolution of marine turtle stock composition in fishery bycatch: a case study in the Mediterranean.

    L. Laurent;P. Casale;M. N. Bradai;B. J. Godley

  • exRNA Atlas Analysis Reveals Distinct Extracellular RNA Cargo Types and Their Carriers Present across Human Biofluids

    Oscar D. Murillo;William Thistlethwaite;Joel Rozowsky;Sai Lakshmi Subramanian

  • The Neonatal and Adult Human Testis Defined at the Single-Cell Level

    Abhishek Sohni;Kun Tan;Hye Won Song;Dana Burow

  • Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.

    Guang-Hui Liu;Keiichiro Suzuki;Jing Qu;Ignacio Sancho-Martinez

  • Comprehensive MicroRNA Profiling Reveals a Unique Human Embryonic Stem Cell Signature Dominated by a Single Seed Sequence

    Louise C Laurent;Louise C Laurent;Jing Chen;Igor Ulitsky;Franz-Josef Mueller

Frequent Co-Authors

Jeanne F. Loring
Jeanne F. Loring Scripps Research Institute
Ying Liu
Ying Liu The University of Texas Health Science Center at Houston
David J. Galas
David J. Galas Pacific Northwest Diabetes Research Institute
Xandra O. Breakefield
Xandra O. Breakefield Harvard University
David J. Erle
David J. Erle University of California, San Francisco
Rob Knight
Rob Knight University of California, San Diego
Evan Y. Snyder
Evan Y. Snyder Discovery Institute
Shoukhrat Mitalipov
Shoukhrat Mitalipov Oregon Health & Science University
Hong Ma
Hong Ma Pennsylvania State University

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