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Biology and Biochemistry

D-Index
50
Citations
11927
World Ranking
17492
National Ranking
7183

Overview

Shoukhrat Mitalipov is affiliated with Oregon Health & Science University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology and its applications in reproduction and genetics.

The scientist's recent publications include work on human follicular development and assisted reproductive technologies. Selected papers demonstrate a focus on reproductive biology, gene editing, and mitochondrial genetics:

  • Matrix-free 3D culture supports human follicular development from the unilaminar to the antral stage in vitro yielding morphologically normal metaphase II oocytes (2021) in Human Reproduction
  • First pilot study of maternal spindle transfer for the treatment of repeated in vitro fertilization failures in couples with idiopathic infertility (2023) in Fertility and Sterility
  • FREQUENT GENE CONVERSION IN HUMAN EMBRYOS INDUCED BY DOUBLE STRAND BREAKS (2020) in bioRxiv (Cold Spring Harbor Laboratory)
  • Germline transmission of donor, maternal and paternal mtDNA in primates (2020) in Human Reproduction
  • Limitations of gene editing assessments in human preimplantation embryos (2023) in Nature Communications

Mitalipov's research interests are reflected in recurring topics such as pluripotent stem cells, CRISPR and genetic engineering, reproductive biology and fertility, mitochondrial function and pathology, metabolism and genetic disorders, assisted reproductive technology, and animal genetics and reproduction.

  • Pluripotent Stem Cells Research
  • CRISPR and Genetic Engineering
  • Reproductive Biology and Fertility
  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Animal Genetics and Reproduction

The scientist frequently publishes in journals relevant to fertility and human reproduction. Key publication venues include:

  • Fertility and Sterility
  • Human Reproduction
  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE

Frequent coauthors collaborating with Mitalipov include:

  • Aleksei Mikhalchenko
  • Amy Koski
  • Hong Ma
  • Crystal Van Dyken
  • Paula Amato

Mitalipov's main fields of study encompass:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Subfields of particular focus include molecular biology, clinical biochemistry, reproductive medicine, pediatrics, perinatology, and public health aspects related to environmental and occupational health.

  • Molecular Biology
  • Public Health, Environmental and Occupational Health
  • Clinical Biochemistry
  • Pediatrics, Perinatology and Child Health
  • Reproductive Medicine

Best Publications

  • Correction of a pathogenic gene mutation in human embryos

    Hong Ma;Nuria Marti-Gutierrez;Sang Wook Park;Jun Wu

  • Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer

    Masahito Tachibana;Paula Amato;Michelle Sparman;Nuria Marti Gutierrez

  • Producing primate embryonic stem cells by somatic cell nuclear transfer

    J. A. Byrne;D. A. Pedersen;L. L. Clepper;M. Nelson

  • Mitochondrial gene replacement in primate offspring and embryonic stem cells

    Masahito Tachibana;Michelle Sparman;Hathaitip Sritanaudomchai;Hong Ma

  • Totipotency, pluripotency and nuclear reprogramming.

    Shoukhrat Mitalipov;Don Wolf

  • Towards germline gene therapy of inherited mitochondrial diseases

    Masahito Tachibana;Paula Amato;Michelle Sparman;Joy Woodward

  • Spermatogonial Stem Cell Transplantation into Rhesus Testes Regenerates Spermatogenesis Producing Functional Sperm

    Brian Peter Hermann;Meena Sukhwani;Felicity Winkler;Julia N. Pascarella

  • A purified population of multipotent cardiovascular progenitors derived from primate pluripotent stem cells engrafts in postmyocardial infarcted nonhuman primates

    Guillaume Blin;David Nury;Sonia Stefanovic;Tui Neri

  • Abnormalities in human pluripotent cells due to reprogramming mechanisms

    Hong Ma;Robert Morey;Ryan C. O'Neil;Ryan C. O'Neil;Yupeng He;Yupeng He

  • Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations

    Eunju Kang;Eunju Kang;Jun Wu;Nuria Marti Gutierrez;Amy Koski

  • Brains, Genes, and Primates

    Juan Carlos Izpisua Belmonte;Edward M. Callaway;Sarah J. Caddick;Patricia Churchland

  • Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs

    Eunju Kang;Eunju Kang;Xinjian Wang;Rebecca Tippner-Hedges;Rebecca Tippner-Hedges;Hong Ma;Hong Ma

  • Cell cycle features of primate embryonic stem cells

    Anne Catherine Fluckiger;Anne Catherine Fluckiger;Guillaume Marcy;Guillaume Marcy;Mélanie Marchand;Mélanie Marchand;Didier Négre;Didier Négre;Didier Négre

  • Metabolic rescue in pluripotent cells from patients with mtDNA disease

    Hong Ma;Clifford D.L. Folmes;Jun Wu;Robert Morey

  • Generation of Chimeric Rhesus Monkeys

    Masahito Tachibana;Michelle Sparman;Cathy Ramsey;Hong Ma

  • Mitochondrial replacement therapy in reproductive medicine

    Don P. Wolf;Don P. Wolf;Nargiz Mitalipov;Nargiz Mitalipov;Shoukhrat Mitalipov;Shoukhrat Mitalipov

  • Isolation and characterization of novel rhesus monkey embryonic stem cell lines.

    Shoukhrat Mitalipov;Hung Chih Kuo;James Byrne;Lisa Clepper

  • Rhesus Monkey Embryos Produced by Nuclear Transfer from Embryonic Blastomeres or Somatic Cells

    Shoukhrat M. Mitalipov;Richard R. Yeoman;Kevin D. Nusser;Don P. Wolf

  • Rapid mitochondrial DNA segregation in primate preimplantation embryos precedes somatic and germline bottleneck

    Hyo Sang Lee;Hong Ma;Rita Cervera Juanes;Masahito Tachibana

  • Correction of a pathogenic gene mutation in human embryos

    Ma H;Marti-Gutierrez N;Park Sw;Wu J

Frequent Co-Authors

Don P. Wolf
Don P. Wolf Oregon Health & Science University
Hong Ma
Hong Ma Pennsylvania State University
Jun Wu
Jun Wu The University of Texas Southwestern Medical Center
Richard L. Stouffer
Richard L. Stouffer Oregon Health & Science University
Sanjiv Kaul
Sanjiv Kaul Oregon Health & Science University
Louise C. Laurent
Louise C. Laurent University of California, San Diego
Andre Terzic
Andre Terzic Mayo Clinic
Susan B. Olson
Susan B. Olson Oregon Health & Science University
Qi Zhou
Qi Zhou Chinese Academy of Sciences

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