World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
21990
World Ranking
4324
National Ranking
127

Overview

Guang-Hui Liu is affiliated with the Chinese Academy of Sciences in China and has a research portfolio primarily focused on biochemistry, genetics, molecular biology, and medicine. Their scientific output spans multiple subfields including molecular biology, physiology, aging, immunology, and cancer research. The body of work covers key topics such as genetics, aging and longevity in model organisms, single-cell and spatial transcriptomics, epigenetics and DNA methylation, telomeres, telomerase, and senescence, RNA modifications and cancer, CRISPR and genetic engineering, and adipose tissue and metabolism.

Throughout their career, Guang-Hui Liu has contributed to over 300 publications with a notable presence in several prominent academic journals. Frequent publication venues include:

  • Protein & Cell
  • Nucleic Acids Research
  • Life Medicine
  • Nature Aging
  • Cell

Their collaborative network includes repeated coauthorship with several researchers such as Jing Qu, Weiqi Zhang, Si Wang, Juan Carlos Izpisúa Belmonte, and Moshi Song. These collaborations reflect ongoing research relationships across a variety of topics within their scientific domains.

Among their recent papers are studies focused on genomic and aging-related science, including:

  • "Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022," published in 2021 in Nucleic Acids Research
  • "Single-Cell Transcriptomic Atlas of Primate Ovarian Aging," published in 2020 in Cell
  • "Epigenetic regulation of aging: implications for interventions of aging and diseases," published in 2022 in Signal Transduction and Targeted Therapy
  • "Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2021," published in 2020 in Nucleic Acids Research
  • "The ageing epigenome and its rejuvenation," published in 2020 in Nature Reviews Molecular Cell Biology

The themes of these publications include database resources supporting genomics research in China, single-cell analysis of aging in primates, and epigenetic mechanisms underlying aging and associated diseases.

Best Publications

  • In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

    Keiichiro Suzuki;Yuji Tsunekawa;Reyna Hernández-Benítez;Reyna Hernández-Benítez;Jun Wu;Jun Wu

  • NF-κB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK

    Guang-Hui Liu;Jing Qu;Xun Shen;Xun Shen

  • Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

    Guang Hui Liu;Basam Z. Barkho;Sergio Ruiz;Dinh Diep

  • A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

    Weiqi Zhang;Jingyi Li;Keiichiro Suzuki;Jing Qu

  • Repression of the Antioxidant NRF2 Pathway in Premature Aging.

    Nard Kubben;Weiqi Zhang;Lixia Wang;Ty C. Voss

  • Single-Cell Transcriptomic Atlas of Primate Ovarian Aging

    Si Wang;Yuxuan Zheng;Jingyi Li;Yang Yu

  • Mitochondrial Regulation in Pluripotent Stem Cells

    Xiuling Xu;Shunlei Duan;Fei Yi;Alejandro Ocampo

  • Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

    Guang-Hui Liu;Guang-Hui Liu;Jing Qu;Jing Qu;Keiichiro Suzuki;Emmanuel Nivet

  • The ageing epigenome and its rejuvenation.

    Weiqi Zhang;Jing Qu;Guang-Hui Liu;Juan Carlos Izpisua Belmonte

  • Selective elimination of mitochondrial mutations in the germline by genome editing

    Pradeep Reddy;Alejandro Ocampo;Keiichiro Suzuki;Jinping Luo

  • SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.

    Huize Pan;Di Guan;Xiaomeng Liu;Jingyi Li

  • Inflammasomes in cancer: a double-edged sword

    Ryan Kolb;Guang-Hui Liu;Guang-Hui Liu;Ann M. Janowski;Fayyaz S. Sutterwala;Fayyaz S. Sutterwala

  • Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging.

    Shuai Ma;Shuhui Sun;Lingling Geng;Lingling Geng;Moshi Song

  • Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.

    Guang-Hui Liu;Keiichiro Suzuki;Jing Qu;Ignacio Sancho-Martinez

  • Regulation of Stem Cell Aging by Metabolism and Epigenetics.

    Ruotong Ren;Ruotong Ren;Alejandro Ocampo;Guang-Hui Liu;Juan Carlos Izpisua Belmonte

  • A Single-Cell Transcriptomic Atlas of Human Skin Aging

    Zhiran Zou;Xiao Long;Qian Zhao;Yandong Zheng

  • Epigenetic Modifications in Cardiovascular Aging and Diseases.

    Weiqi Zhang;Moshi Song;Jing Qu;Guang-Hui Liu

  • A human circulating immune cell landscape in aging and COVID-19.

    Yingfeng Zheng;Xiuxing Liu;Wenqing Le;Lihui Xie

  • Aging Atlas: a multi-omics database for aging biology

    Guang-Hui Liu;Yiming Bao;Jing Qu

  • Targeted Gene Correction Minimally Impacts Whole-Genome Mutational Load in Human-Disease-Specific Induced Pluripotent Stem Cell Clones

    Keiichiro Suzuki;Chang Yu;Jing Qu;Mo Li

Frequent Co-Authors

Concepcion Rodriguez Esteban
Concepcion Rodriguez Esteban Salk Institute for Biological Studies
Jun Wu
Jun Wu The University of Texas Southwestern Medical Center
Fuchou Tang
Fuchou Tang Peking University
Qi Zhou
Qi Zhou Chinese Academy of Sciences
Kun Zhang
Kun Zhang University of California, San Diego
Christopher Benner
Christopher Benner University of California, San Diego
Josep M. Campistol
Josep M. Campistol University of Barcelona
John R. Yates
John R. Yates Scripps Research Institute
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital

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