His primary areas of investigation include Immunology, Cell biology, T cell, Antigen and Cytotoxic T cell. His Immunology research incorporates elements of Melanoma, Lung and Cell–cell interaction. Many of his research projects under Cell biology are closely connected to Concentric ring with Concentric ring, tying the diverse disciplines of science together.
His Antigen study combines topics in areas such as Live cell imaging and Antigen presentation. The Cytotoxic T cell study which covers Tumor microenvironment that intersects with Immunotherapy and Cell type. His Antigen-presenting cell study combines topics from a wide range of disciplines, such as IL-2 receptor and CD40.
His scientific interests lie mostly in Cell biology, Immunology, T cell, Immune system and Cytotoxic T cell. His work carried out in the field of Cell biology brings together such families of science as Immunological synapse, T-cell receptor, Synapse and Cytoskeleton. His research integrates issues of Receptor and Lung in his study of Immunology.
In his research on the topic of T cell, Antigen presentation is strongly related with Antigen. His biological study spans a wide range of topics, including Cancer, Cancer research and Cell. His Antigen-presenting cell research integrates issues from Interleukin 21 and CD40.
His primary areas of study are Immune system, Cell, Cancer research, Immunology and Cancer. His Immune system study integrates concerns from other disciplines, such as Antibody and Flow cytometry. His Cell research is multidisciplinary, incorporating elements of Phenotype and Computational biology.
His study in Cancer research is interdisciplinary in nature, drawing from both Nippostrongylus brasiliensis, Lung injury, In vivo and Immunotherapy. His studies deal with areas such as T cell, Cytotoxic T cell, Melanoma and Antigen as well as Immunotherapy. His work in the fields of Immunology, such as Immunity and Inflammation, intersects with other areas such as Viral load.
Matthew F. Krummel spends much of his time researching Cancer research, Cell, Immune system, Tumor microenvironment and Cancer. His Immune system research is within the category of Immunology. His Tumor microenvironment study incorporates themes from Myeloid, Blockade, Innate immune system and Adoptive cell transfer.
His work on Immunotherapy as part of general Cancer study is frequently connected to Functional activity, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. The study incorporates disciplines such as Epithelial–mesenchymal transition, T cell and Macrophage chemotaxis in addition to Immunotherapy. The concepts of his Antigen study are interwoven with issues in Cytotoxic T cell and Cell biology.
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Enhancement of antitumor immunity by CTLA-4 blockade.
Dana R. Leach;Matthew F. Krummel;James P. Allison.
Science (1996)
Understanding the tumor immune microenvironment (TIME) for effective therapy.
Mikhail Binnewies;Edward W. Roberts;Kelly Kersten;Vincent Chan.
Nature Medicine (2018)
CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.
Matthew F. Krummel;James P. Allison.
Journal of Experimental Medicine (1995)
CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.
Matthew F. Krummel;James P. Allison.
Journal of Experimental Medicine (1996)
Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice
Qizhi Tang;Jason Yeates Adams;Aaron J. Tooley;Mingying Bi.
Nature Immunology (2006)
Type 2 innate lymphoid cells control eosinophil homeostasis
Jesse C. Nussbaum;Steven J. Van Dyken;Jakob Von Moltke;Laurence E. Cheng.
Nature (2013)
Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity
Miranda L. Broz;Mikhail Binnewies;Bijan Boldajipour;Amanda E. Nelson.
Cancer Cell (2014)
Dendritic cells in cancer immunology and immunotherapy.
Stefanie K Wculek;Francisco J Cueto;Adriana M Mujal;Ignacio Melero.
Nature Reviews Immunology (2020)
The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors
Emma Lefrançais;Guadalupe Ortiz-Muñoz;Axelle Caudrillier;Beñat Mallavia.
Nature (2017)
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.
Brian T Fife;Kristen E Pauken;Todd N Eagar;Takashi Obu.
Nature Immunology (2009)
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