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Immunology

D-Index
83
Citations
45432
World Ranking
1411
National Ranking
719

Overview

Matthew F. Krummel is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with significant contributions to immunology, oncology, molecular biology, infectious diseases, and neurology. The main focus of their work includes immune cells in cancer, immune cell function and interaction, immunotherapy and immune responses, cancer immunotherapy and biomarkers, T-cell and B-cell immunology, CAR-T cell therapy research, and COVID-19 clinical research studies.

The scientist has published extensively, with frequent contributions in venues such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, SSRN Electronic Journal, Cancer Cell, and The Journal of Experimental Medicine.

Recent notable papers authored or co-authored by Matthew F. Krummel include:

  • The NK cell-cancer cycle: advances and new challenges in NK cell-based immunotherapies, 2020, Nature Immunology
  • SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution, 2020, Cell Metabolism
  • Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted in metastatic lymph nodes, 2023, Cell
  • Targeting TREM2 on tumor-associated macrophages enhances immunotherapy, 2021, Cell Reports
  • Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer, 2022, Cancer Cell

Matthew F. Krummel has collaborated frequently with a group of co-authors including Alexis J. Combes, David J. Erle, Bushra Samad, Kenneth H. Hu, and Charles Langelier.

Research topics central to their work are:

  • Immune cells in cancer
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Cancer Immunotherapy and Biomarkers
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • COVID-19 Clinical Research Studies

Their notable publication venues are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • SSRN Electronic Journal
  • Cancer Cell
  • The Journal of Experimental Medicine

Research fields covered by Matthew F. Krummel include:

  • Medicine
  • Immunology and Microbiology

Subfields of study within these broader areas include:

  • Immunology
  • Oncology
  • Molecular Biology
  • Infectious Diseases
  • Neurology

Best Publications

  • Understanding the tumor immune microenvironment (TIME) for effective therapy.

    Mikhail Binnewies;Edward W. Roberts;Kelly Kersten;Vincent Chan

  • Enhancement of antitumor immunity by CTLA-4 blockade.

    Dana R. Leach;Matthew F. Krummel;James P. Allison

  • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation.

    Matthew F. Krummel;James P. Allison

  • Dendritic cells in cancer immunology and immunotherapy.

    Stefanie K Wculek;Francisco J Cueto;Adriana M Mujal;Ignacio Melero

  • CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells.

    Matthew F. Krummel;James P. Allison

  • Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity

    Miranda L. Broz;Mikhail Binnewies;Bijan Boldajipour;Amanda E. Nelson

  • The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors

    Emma Lefrançais;Guadalupe Ortiz-Muñoz;Axelle Caudrillier;Beñat Mallavia

  • Type 2 innate lymphoid cells control eosinophil homeostasis

    Jesse C. Nussbaum;Steven J. Van Dyken;Jakob Von Moltke;Laurence E. Cheng

  • Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma

    Edward W. Roberts;Miranda L. Broz;Mikhail Binnewies;Mark B. Headley

  • A natural killer-dendritic cell axis defines checkpoint therapy-responsive tumor microenvironments.

    Kevin C. Barry;Joy Hsu;Miranda L. Broz;Francisco J. Cueto;Francisco J. Cueto;Francisco J. Cueto

  • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

    Qizhi Tang;Jason Yeates Adams;Aaron J. Tooley;Mingying Bi

  • Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function.

    Brigid L.M. Hogan;Christina E. Barkauskas;Harold A. Chapman;Jonathan A. Epstein

  • Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.

    Brian T Fife;Kristen E Pauken;Todd N Eagar;Takashi Obu

  • Antigen-Engaged B Cells Undergo Chemotaxis toward the T Zone and Form Motile Conjugates with Helper T Cells

    Takaharu Okada;Mark J Miller;Ian Parker;Matthew F Krummel

  • Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T cell Immunity

    Mikhail Binnewies;Adriana M. Mujal;Joshua L. Pollack;Alexis J. Combes

  • Dissecting the Tumor Myeloid Compartment Reveals Rare Activating Antigen-Presenting Cells Critical for T Cell Immunity.

    Unknown

  • Tumor immune profiling predicts response to anti–PD-1 therapy in human melanoma

    Adil I. Daud;Kimberly Loo;Mariela L. Pauli;Robert Sanchez-Rodriguez

  • Deletional Tolerance Mediated by Extrathymic Aire-Expressing Cells

    James M. Gardner;Jason J. DeVoss;Rachel S. Friedman;David J. Wong

  • Liver Metastasis and Treatment Outcome with Anti-PD-1 Monoclonal Antibody in Patients with Melanoma and NSCLC

    Paul C. Tumeh;Matthew D. Hellmann;Omid Hamid;Katy K. Tsai

  • Differential Clustering of CD4 and CD3ζ During T Cell Recognition

    Matthew F. Krummel;Michael D. Sjaastad;Christoph Wülfing;Mark M. Davis

  • Visualization of immediate immune responses to pioneer metastatic cells in the lung

    Mark B. Headley;Adriaan Bins;Alyssa Nip;Edward W. Roberts

Frequent Co-Authors

David J. Erle
David J. Erle University of California, San Francisco
James P. Allison
James P. Allison The University of Texas MD Anderson Cancer Center
Adil Daud
Adil Daud University of California, San Francisco
Michael Rosenblum
Michael Rosenblum University of California, San Francisco
Mikala Egeblad
Mikala Egeblad Cold Spring Harbor Laboratory
Zena Werb
Zena Werb University of California, San Francisco
Prescott G. Woodruff
Prescott G. Woodruff University of California, San Francisco
Andrew J. Ewald
Andrew J. Ewald Johns Hopkins University School of Medicine
Mark M. Davis
Mark M. Davis Stanford University
Philippe Pierre
Philippe Pierre Aix-Marseille University

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