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Neuroscience

D-Index
46
Citations
7839
World Ranking
6709
National Ranking
296

Overview

Alain Buisson is affiliated with Grenoble Alpes University in France and has contributed extensively to research in the fields of Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Their subfields of study include Physiology, Molecular Biology, Cellular and Molecular Neuroscience, Pharmacology, and Neurology.

The main topics of Alain Buisson's research revolve around Alzheimer's disease research and treatments, Neuroscience and Neuropharmacology Research, Cholinesterase and Neurodegenerative Diseases, as well as Mitochondrial Function and Pathology. Additionally, their work spans Inflammatory Bowel Disease, Computational Drug Discovery Methods, and Medicinal Plants and Neuroprotection.

Recent publications by Alain Buisson include the following papers:

  • Astrocyte-neuron interplay is critical for Alzheimer's disease pathogenesis and is rescued by TRPA1 channel blockade, 2021, Brain
  • Treating early postnatal circuit defect delays Huntington's disease onset and pathology in mice, 2022, Science
  • Tubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease, 2021, Brain
  • VEGF counteracts amyloid-β-induced synaptic dysfunction, 2021, Cell Reports
  • Density of GABAB Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer's Disease, 2020, International Journal of Molecular Sciences

Alain Buisson frequently publishes in several journals, including:

  • Journal of Crohn s and Colitis
  • Brain
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Cell Reports

Collaboration is a significant aspect of their research, with frequent coauthors including:

  • Fabien Lanté
  • Muriel R. Jacquier-Sarlin
  • Eve Borel
  • Sylvie Boisseau
  • José Martínez Hernández

This profile reflects Alain Buisson's multidisciplinary scientific contributions, focusing on neurodegenerative diseases and related molecular mechanisms.

Best Publications

  • The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

    Olivier Nicole;Fabian Docagne;Carine Ali;Isabelle Margaill

  • Neuronal viability is controlled by a functional relation between synaptic and extrasynaptic NMDA receptors

    F. Léveillé;F. El gaamouch;E. Gouix;M. Lecocq

  • Activity-Dependent Tau Protein Translocation to Excitatory Synapse Is Disrupted by Exposure to Amyloid-Beta Oligomers

    Marie Lise Frandemiche;Marie Lise Frandemiche;Sandrine De Seranno;Sandrine De Seranno;Travis Rush;Travis Rush;Eve Borel;Eve Borel

  • Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitoxicity in the brain

    Carine Ali;Olivier Nicole;Fabian Docagne;Sylvain Lesne

  • The neuroprotective effect of a nitric oxide inhibitor in a rat model of focal cerebral ischaemia.

    A. Buisson;M. Plotkine;R.G. Boulu

  • NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production

    Sylvain Lesné;Carine Ali;Cecília Gabriel;Nicole Croci

  • Activation of extrasynaptic, but not synaptic, NMDA receptors modifies amyloid precursor protein expression pattern and increases amyloid-ß production

    Karim Bordji;Javier Becerril-Ortega;Olivier Nicole;Alain Buisson

  • Neuroprotection Mediated by Glial Cell Line-Derived Neurotrophic Factor: Involvement of a Reduction of NMDA-Induced Calcium Influx by the Mitogen-Activated Protein Kinase Pathway

    Olivier Nicole;Carine Ali;Fabian Docagne;Laurent Plawinski

  • Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline.

    Mélissa Glatigny;Stéphanie Moriceau;Manon Rivagorda;Mariana Ramos-Brossier

  • Mechanisms Involved in the Neuroprotective Activity of a Nitric Oxide Synthase Inhibitor During Focal Cerebral Ischemia

    A. Buisson;I. Margaill;J. Callebert;M. Plotkine

  • Nitric oxide: an endogenous anticonvulsant substance.

    Buisson A;Lakhmeche N;Verrecchia C;Plotkine M

  • The inhibitory mGluR agonist, s-4-carboxy-3-hydroxy-phenylglycine selectively attenuates NMDA neurotoxicity and oxygen-glucose deprivation-induced neuronal death

    A. Buisson;D.W. Choi

  • A transforming growth factor-beta antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury.

    Antonio Ruocco;Olivier Nicole;Fabian Docagne;Carine Ali

  • Transforming Growth Factor-β1 Potentiates Amyloid-β Generation in Astrocytes and in Transgenic Mice

    Sylvain Lesné;Fabian Docagne;Cecı́lia Gabriel;Géraldine Liot

  • Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor β1

    Alain Buisson;Olivier Nicole;Fabian Docagne;Hervé Sartelet

  • Reduction of Ischemic Brain Damage by Nitrous Oxide and Xenon

    Helene N David;Frederic Leveille;Laurent Chazalviel;Eric T MacKenzie

  • Transforming growth factor-beta and ischemic brain injury.

    Alain Buisson;Sylvain Lesne;Fabian Docagne;Carine Ali

  • Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease

    Javier Becerril-Ortega;Karim Bordji;Thomas Fréret;Travis Rush;Travis Rush

  • The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.

    Fatou Amar;Mathew A. Sherman;Travis Rush;Megan Larson

  • Complement anaphylatoxin C3a is selectively protective against NMDA-induced neuronal cell death.

    Johan Van Beek;Olivier Nicole;Carine Ali;Alexander Ischenko

Frequent Co-Authors

Denis Vivien
Denis Vivien Université de Caen Normandie
Fabian Docagne
Fabian Docagne Université de Caen Normandie
Sylvain Lesné
Sylvain Lesné University of Minnesota
Dennis W. Choi
Dennis W. Choi Stony Brook University
David Blum
David Blum University of Lille
Rafael Luján
Rafael Luján University of Castilla-La Mancha
Ryuichi Shigemoto
Ryuichi Shigemoto Institute of Science and Technology Austria
Charles Auffray
Charles Auffray Centre national de la recherche scientifique, CNRS
Yugo Fukazawa
Yugo Fukazawa University of Fukui
Marc Savasta
Marc Savasta Grenoble Alpes University

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