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D-Index & Metrics

Neuroscience

D-Index
34
Citations
9694
World Ranking
9254
National Ranking
3904

Sylvain Lesné publication distribution in Neuroscience in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Neuroscience in 2026. The highlighted bar marks where Sylvain Lesné sits on this spectrum.

38–47 publications: 18 scientists 48–57 publications: 79 scientists 58–67 publications: 193 scientists 68–77 publications: 323 scientists 78–87 publications: 406 scientists 88–97 publications: 452 scientists 98–107 publications: 539 scientists 108–117 publications: 505 scientists 118–127 publications: 522 scientists 128–137 publications: 469 scientists 138–147 publications: 456 scientists 148–157 publications: 459 scientists 158–167 publications: 397 scientists 168–177 publications: 383 scientists 178–187 publications: 350 scientists 188–197 publications: 302 scientists 198–207 publications: 306 scientists 208–217 publications: 262 scientists 218–227 publications: 242 scientists 228–237 publications: 220 scientists 238–247 publications: 203 scientists 248–257 publications: 174 scientists 258–267 publications: 176 scientists 268–277 publications: 175 scientists 278–287 publications: 125 scientists 288–297 publications: 116 scientists 298–307 publications: 127 scientists 308–317 publications: 128 scientists 318–327 publications: 99 scientists 328–337 publications: 89 scientists 338–347 publications: 78 scientists 348–357 publications: 96 scientists 358–367 publications: 66 scientists 368–377 publications: 59 scientists 378–387 publications: 65 scientists 388–397 publications: 54 scientists 398–407 publications: 48 scientists 408–417 publications: 49 scientists 418–427 publications: 34 scientists 428–437 publications: 31 scientists 438–447 publications: 30 scientists 448–457 publications: 31 scientists 458–467 publications: 36 scientists 468–477 publications: 40 scientists 478–487 publications: 35 scientists 488–497 publications: 30 scientists 498–507 publications: 23 scientists 508–517 publications: 26 scientists 518–527 publications: 20 scientists 528–537 publications: 23 scientists 538–547 publications: 20 scientists 548–557 publications: 20 scientists 558–567 publications: 17 scientists 568–577 publications: 14 scientists 578–587 publications: 20 scientists 588–597 publications: 20 scientists 598–607 publications: 19 scientists 608–617 publications: 18 scientists 618–627 publications: 17 scientists 628–637 publications: 11 scientists 638–647 publications: 11 scientists 648–657 publications: 11 scientists 658–667 publications: 8 scientists 668–677 publications: 7 scientists 678–687 publications: 11 scientists 688–697 publications: 10 scientists 698–707 publications: 4 scientists 708–717 publications: 6 scientists 718–727 publications: 5 scientists 728–737 publications: 5 scientists 738–747 publications: 9 scientists 748–757 publications: 9 scientists 758–767 publications: 3 scientists 768–777 publications: 7 scientists 778–787 publications: 7 scientists 788–797 publications: 6 scientists 798–807 publications: 2 scientists 808–817 publications: 2 scientists 818–827 publications: 7 scientists 828–837 publications: 0 scientists 838–847 publications: 9 scientists 848–857 publications: 3 scientists 858–867 publications: 1 scientists 868–877 publications: 3 scientists 878–886 publications: 6 scientists 887+ publications: 100 scientists
38 publications 887+

This scientist: 57 publications — 1st percentile

1% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 887 publications or more.

Sylvain Lesné D-index placement in Neuroscience in 2026

The chart shows the D-index (discipline H-index) distribution of Neuroscience scientists ranked by Research.com in 2026. The highlighted bar marks where Sylvain Lesné sits on this spectrum.

30–31 D-Index: 42 scientists 32–33 D-Index: 172 scientists 34–35 D-Index: 296 scientists 36–37 D-Index: 435 scientists 38–39 D-Index: 459 scientists 40–41 D-Index: 456 scientists 42–43 D-Index: 467 scientists 44–45 D-Index: 478 scientists 46–47 D-Index: 512 scientists 48–49 D-Index: 435 scientists 50–51 D-Index: 425 scientists 52–53 D-Index: 418 scientists 54–55 D-Index: 392 scientists 56–57 D-Index: 357 scientists 58–59 D-Index: 334 scientists 60–61 D-Index: 328 scientists 62–63 D-Index: 260 scientists 64–65 D-Index: 278 scientists 66–67 D-Index: 239 scientists 68–69 D-Index: 250 scientists 70–71 D-Index: 210 scientists 72–73 D-Index: 200 scientists 74–75 D-Index: 189 scientists 76–77 D-Index: 170 scientists 78–79 D-Index: 146 scientists 80–81 D-Index: 113 scientists 82–83 D-Index: 126 scientists 84–85 D-Index: 100 scientists 86–87 D-Index: 84 scientists 88–89 D-Index: 99 scientists 90–91 D-Index: 84 scientists 92–93 D-Index: 85 scientists 94–95 D-Index: 72 scientists 96–97 D-Index: 76 scientists 98–99 D-Index: 45 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 43 scientists 104–105 D-Index: 32 scientists 106–107 D-Index: 45 scientists 108–109 D-Index: 50 scientists 110–111 D-Index: 32 scientists 112–113 D-Index: 39 scientists 114–115 D-Index: 32 scientists 116–117 D-Index: 29 scientists 118–119 D-Index: 27 scientists 120–121 D-Index: 19 scientists 122–123 D-Index: 23 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 16 scientists 128–129 D-Index: 24 scientists 130–131 D-Index: 13 scientists 132–133 D-Index: 21 scientists 134–135 D-Index: 17 scientists 136–137 D-Index: 14 scientists 138–139 D-Index: 15 scientists 140–141 D-Index: 10 scientists 142–143 D-Index: 10 scientists 144–145 D-Index: 13 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 8 scientists 150–151 D-Index: 6 scientists 152–153 D-Index: 6 scientists 154–155 D-Index: 7 scientists 156–157 D-Index: 7 scientists 158–159 D-Index: 10 scientists 160–161 D-Index: 4 scientists 162 D-Index: 8 scientists 163+ D-Index: 100 scientists
30 D-Index 163+

This scientist: 34 D-Index — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 163 D-Index or more.

Overview

Sylvain Lesné is affiliated with the University of Minnesota in the United States. Their research primarily spans the fields of Medicine and Neuroscience, with significant contributions in related subfields including Neurology, Cellular and Molecular Neuroscience, Physiology, Pharmacology, and Molecular Biology.

Their work covers several main topics, notably:

  • Parkinson's Disease Mechanisms and Treatments
  • Alzheimer's Disease Research and Treatments
  • Nuclear Receptors and Signaling
  • Amyotrophic Lateral Sclerosis Research
  • Cholinesterase and Neurodegenerative Diseases
  • RNA Regulation and Disease
  • Stress Responses and Cortisol

Lesné's publications appear frequently in journals such as:

  • Acta Neuropathologica Communications
  • Chemical Reviews
  • Journal of Parkinson's Disease
  • Nature
  • Brain

Some recent papers include:

  • "Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer's Disease, Parkinson's Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis," 2021, Chemical Reviews
  • "Soluble endogenous oligomeric α-synuclein species in neurodegenerative diseases: Expression, spreading, and cross-talk," 2020, Journal of Parkinson's Disease
  • "Retraction Note: A specific amyloid-β protein assembly in the brain impairs memory," 2024, Nature
  • "SNCA genetic lowering reveals differential cognitive function of alpha-synuclein dependent on sex," 2022, Acta Neuropathologica Communications
  • "Correction to: Brain amyloid-β oligomers in ageing and Alzheimer's disease," 2022, Brain

Frequent co-authors in Lesné's work include:

  • Rakez Kayed
  • Mathew A. Sherman
  • Jennifer L. Brown
  • Damyan W. Hart
  • Bikash R. Sahoo

Best Publications

  • A specific amyloid-|[beta]| protein assembly in the brain impairs memory

    Sylvain Lesné;Ming Teng Koh;Linda Kotilinek;Rakez Kayed

  • Amyloid oligomers: A joint experimental/computational perspective on Alzheimer's disease, Parkinson's disease, type II diabetes, and amyotrophic lateral sclerosis

    Phuong H. Nguyen;Ayyalusamy Ramamoorthy;Bikash R. Sahoo;Jie Zheng

  • Accelerating Amyloid-β Fibrillization Reduces Oligomer Levels and Functional Deficits in Alzheimer Disease Mouse Models *

    Irene H. Cheng;Kimberly Scearce-Levie;Kimberly Scearce-Levie;Justin Legleiter;Justin Legleiter;Jorge J. Palop;Jorge J. Palop

  • Brain amyloid-β oligomers in ageing and Alzheimer’s disease

    Sylvain E Lesne;Mathew A Sherman;Marianne Grant;Michael A Kuskowski

  • Soluble Aβ oligomer production and toxicity

    Megan E. Larson;Sylvain E. Lesné

  • The Complex PrPc-Fyn Couples Human Oligomeric Aβ with Pathological Tau Changes in Alzheimer's Disease

    Megan Larson;Mathew A. Sherman;Fatou Amar;Mario Ulisse Nuvolone;Mario Ulisse Nuvolone

  • Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitoxicity in the brain

    Carine Ali;Olivier Nicole;Fabian Docagne;Sylvain Lesne

  • Cyclooxygenase-2 inhibition improves amyloid-β-mediated suppression of memory and synaptic plasticity

    Linda A. Kotilinek;Marcus A. Westerman;Qinwen Wang;Qinwen Wang;Kimberly Panizzon

  • NMDA Receptor Activation Inhibits α-Secretase and Promotes Neuronal Amyloid-β Production

    Sylvain Lesné;Carine Ali;Cecília Gabriel;Nicole Croci

  • Plaque-bearing mice with reduced levels of oligomeric amyloid-β assemblies have intact memory function

    Sylvain Lesné;Linda Kotilinek;Karen H. Ashe

  • Orally available compound prevents deficits in memory caused by the Alzheimer amyloid‐β oligomers

    Matthew Townsend;James P. Cleary;James P. Cleary;Tapan Mehta;Jacki Hofmeister

  • Transforming Growth Factor-β1 Potentiates Amyloid-β Generation in Astrocytes and in Transgenic Mice

    Sylvain Lesné;Fabian Docagne;Cecı́lia Gabriel;Géraldine Liot

  • Cognitive effects of cell-derived and synthetically-derived Aβ oligomers

    Miranda N. Reed;Jacki J. Hofmeister;Lisa Jungbauer;Alfred T. Welzel

  • Soluble α-synuclein is a novel modulator of Alzheimer's disease pathophysiology.

    Megan E. Larson;Mathew A Sherman;Susan Greimel;Michael A Kuskowski

  • Involvement of β-site APP cleaving enzyme 1 (BACE1) in amyloid precursor protein-mediated enhancement of memory and activity-dependent synaptic plasticity

    Huifang Ma;Sylvain Lesné;Linda Kotilinek;Jill V. Steidl-Nichols;Jill V. Steidl-Nichols

  • β-Amyloid Modulation of Synaptic Transmission and Plasticity

    Deepa V. Venkitaramani;Jeannie Chin;William J. Netzer;Gunnar K. Gouras

  • Transforming growth factor-beta and ischemic brain injury.

    Alain Buisson;Sylvain Lesne;Fabian Docagne;Carine Ali

  • Angiopoietin-1-induced PI3-kinase activation prevents neuronal apoptosis

    S. Valable;A. Bellail;S. Lesné;G. Liot

  • The amyloid-β oligomer Aβ*56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation.

    Fatou Amar;Mathew A. Sherman;Travis Rush;Megan Larson

  • Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer’s disease

    Stephanie I. Alfonso;Julia A. Callender;Basavaraj Hooli;Corina E. Antal

  • Smad3-dependent induction of plasminogen activator inhibitor-1 in astrocytes mediates neuroprotective activity of transforming growth factor-β1 against NMDA-induced necrosis

    Fabian Docagne;Olivier Nicole;Cecilia Gabriel;Mónica Fernández-Monreal

Frequent Co-Authors

Denis Vivien
Denis Vivien Université de Caen Normandie
Alain Buisson
Alain Buisson Grenoble Alpes University
Fabian Docagne
Fabian Docagne Université de Caen Normandie
David A. Bennett
David A. Bennett Rush University Medical Center
Julie A. Schneider
Julie A. Schneider Rush University Medical Center
Michael A. Kuskowski
Michael A. Kuskowski University of Minnesota
Rakez Kayed
Rakez Kayed The University of Texas Medical Branch at Galveston
Jorge J. Palop
Jorge J. Palop University of California, San Francisco
Paul J. Muchowski
Paul J. Muchowski University of California, San Francisco
Lennart Mucke
Lennart Mucke University of California, San Francisco

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