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Neuroscience

D-Index
47
Citations
6848
World Ranking
6517
National Ranking
287

Overview

Fabian Docagne is affiliated with Université de Caen Normandie in France and has a research focus primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology.

The scientist's work spans several subfields including Immunology, Neurology, Genetics, Molecular Biology, and Oncology. Their research topics encompass:

  • Protease and Inhibitor Mechanisms
  • Multiple Sclerosis Research Studies
  • Immunotherapy and Immune Responses
  • Cytokine Signaling Pathways and Interactions
  • Autoimmune Neurological Disorders and Treatments
  • Blood Coagulation and Thrombosis Mechanisms
  • Cell Adhesion Molecules Research

Fabian Docagne has published papers in several peer-reviewed journals including Brain, Journal of Neuroscience, Cellular Immunology, Journal of Neuroinflammation, and Science Translational Medicine.

Notable recent papers include:

  • "Autoimmune encephalitis mediated by B-cell response against N-methyl-d-aspartate receptor" (2020), Brain
  • "Nonionotropic Action of Endothelial NMDA Receptors on Blood-Brain Barrier Permeability via Rho/ROCK-Mediated Phosphorylation of Myosin" (2020), Journal of Neuroscience
  • "Roles of the tissue-type plasminogen activator in immune response" (2021), Cellular Immunology
  • "Ultrasensitive molecular imaging of intestinal mucosal inflammation using leukocyte-mimicking particles targeted to MAdCAM-1 in mice" (2020), Science Translational Medicine
  • "Tissue plasminogen activator worsens experimental autoimmune encephalomyelitis by complementary actions on lymphoid and myeloid cell responses" (2021), Journal of Neuroinflammation

Fabian Docagne collaborates frequently with several researchers, indicating ongoing partnerships in their scientific work. Frequent co-authors include:

  • Denis Vivien
  • Isabelle Bardou
  • Olivier Toutirais
  • Antoine Fournier
  • Erwan Baudron

Best Publications

  • The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.

    Olivier Nicole;Fabian Docagne;Carine Ali;Isabelle Margaill

  • Ischemia-induced interleukin-6 as a potential endogenous neuroprotective cytokine against NMDA receptor-mediated excitoxicity in the brain

    Carine Ali;Olivier Nicole;Fabian Docagne;Sylvain Lesne

  • Cannabinoid CB1 and CB2 Receptors and Fatty Acid Amide Hydrolase Are Specific Markers of Plaque Cell Subtypes in Human Multiple Sclerosis

    Cristina Benito;Juan Pablo Romero;Rosa María Tolón;Diego Clemente

  • Neuroprotection Mediated by Glial Cell Line-Derived Neurotrophic Factor: Involvement of a Reduction of NMDA-Induced Calcium Influx by the Mitogen-Activated Protein Kinase Pathway

    Olivier Nicole;Carine Ali;Fabian Docagne;Laurent Plawinski

  • Therapeutic benefits from nanoparticles: the potential significance of nanoscience in diseases with compromise to the blood brain barrier.

    Silke Krol;Richard Macrez;Fabian Docagne;Gilles Defer

  • Anandamide enhances IL-10 production in activated microglia by targeting CB(2) receptors: roles of ERK1/2, JNK, and NF-kappaB.

    Fernando Correa;Miriam Hernangómez;Leyre Mestre;Frida Loría

  • A transforming growth factor-beta antagonist unmasks the neuroprotective role of this endogenous cytokine in excitotoxic and ischemic brain injury.

    Antonio Ruocco;Olivier Nicole;Fabian Docagne;Carine Ali

  • CINC-1 is an acute-phase protein induced by focal brain injury causing leukocyte mobilization and liver injury.

    Sandra J. Campbell;Paula M. Hughes;John P. Iredale;David C. Wilcockson

  • Transforming Growth Factor-β1 Potentiates Amyloid-β Generation in Astrocytes and in Transgenic Mice

    Sylvain Lesné;Fabian Docagne;Cecı́lia Gabriel;Géraldine Liot

  • Up-regulation of a serine protease inhibitor in astrocytes mediates the neuroprotective activity of transforming growth factor β1

    Alain Buisson;Olivier Nicole;Fabian Docagne;Hervé Sartelet

  • Activation of cannabinoid CB2 receptor negatively regulates IL-12p40 production in murine macrophages: role of IL-10 and ERK1/2 kinase signaling.

    Fernando Gabriel Correa;Leyre Mestre;Fabian Docagne;Carmen Guaza

  • The endocannabinoid system is modulated in response to spinal cord injury in rats.

    Daniel Garcia-Ovejero;Angel Arevalo-Martin;Stefania Petrosino;Fabian Docagne

  • Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide

    Frida Loría;Stefania Petrosino;Leyre Mestre;Alessandra Spagnolo

  • Transforming growth factor-beta and ischemic brain injury.

    Alain Buisson;Sylvain Lesne;Fabian Docagne;Carine Ali

  • Mechanisms of glutamate toxicity in multiple sclerosis: biomarker and therapeutic opportunities

    Richard Macrez;Peter K Stys;Denis Vivien;Stuart A Lipton;Stuart A Lipton

  • HtrA1-dependent proteolysis of TGF- β controls both neuronal maturation and developmental survival

    S. Launay;E. Maubert;N. Lebeurrier;A. Tennstaedt

  • CD200‐CD200R1 interaction contributes to neuroprotective effects of anandamide on experimentally induced inflammation

    Miriam Hernangómez;Leyre Mestre;Fernando Gabriel Correa;Frida Loría

  • Excitotoxicity in a chronic model of multiple sclerosis: Neuroprotective effects of cannabinoids through CB1 and CB2 receptor activation.

    Fabian Docagne;Vilma Muñetón;Diego Clemente;Carine Ali

  • A cannabinoid agonist interferes with the progression of a chronic model of multiple sclerosis by downregulating adhesion molecules.

    L. Mestre;F. Docagne;F. Docagne;F. Correa;F. Loría

  • An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis.

    F. Loría;S. Petrosino;M. Hernangómez;L. Mestre

  • TGFβ1 regulates the inflammatory response during chronic neurodegeneration

    Delphine Boche;Colm Cunningham;Fabian Docagne;Helen Scott

Frequent Co-Authors

Denis Vivien
Denis Vivien Université de Caen Normandie
Alain Buisson
Alain Buisson Grenoble Alpes University
Sylvain Lesné
Sylvain Lesné University of Minnesota
Michel Neunlist
Michel Neunlist University of Nantes
Charles Pierrot-Deseilligny
Charles Pierrot-Deseilligny University of Montpellier
Daniel C. Anthony
Daniel C. Anthony University of Oxford
Stuart A. Lipton
Stuart A. Lipton Scripps Research Institute
Morteza Mahmoudi
Morteza Mahmoudi Michigan State University
Sophie Laurent
Sophie Laurent University of Mons
Charles Auffray
Charles Auffray Centre national de la recherche scientifique, CNRS

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