His scientific interests lie mostly in Neuroscience, Pharmacology, Dopamine, Methamphetamine and Schizophrenia. His Pharmacology research includes elements of NMDA receptor, Neurotoxicity and Moro reflex, Acoustic Startle Reflex. The Dopamine study combines topics in areas such as Agonist and Aggression.
His Methamphetamine research is multidisciplinary, relying on both Haloperidol, Clozapine, GABAB receptor and Baclofen. His work carried out in the field of Schizophrenia brings together such families of science as Innate immune system, Immunology and Phencyclidine. Taku Nagai is doing genetic studies as part of his Internal medicine and Endocrinology and Hippocampus investigations.
Taku Nagai focuses on Neuroscience, Internal medicine, Endocrinology, Dopamine and Pharmacology. In his study, which falls under the umbrella issue of Neuroscience, Immunology is strongly linked to Schizophrenia. His Internal medicine study typically links adjacent topics like Pregnancy.
His Endocrinology research is multidisciplinary, incorporating perspectives in Morphine, Neuroactive steroid, Clozapine and Antagonist. His work in the fields of Nucleus accumbens and Dopaminergic overlaps with other areas such as Meth-. His Nucleus accumbens research incorporates themes from Striatum, Medium spiny neuron, Conditioned place preference, Methamphetamine and Dopamine receptor D1.
His primary areas of investigation include Neuroscience, Cell biology, Schizophrenia, Dopamine and Reelin. His Cell biology study combines topics from a wide range of disciplines, such as Medium spiny neuron and Neuron. His study in the field of Antipsychotic is also linked to topics like Rho kinase inhibitor.
Taku Nagai focuses mostly in the field of Dopamine, narrowing it down to topics relating to Adenosine and, in certain cases, Adenosine A2A receptor. His Nucleus accumbens study is concerned with the larger field of Internal medicine. His Endocrinology study combines topics in areas such as Neuroprotection and In vivo.
His main research concerns Neuroscience, Cell biology, Medium spiny neuron, Dopamine and Dopamine receptor D1. His Neuroscience study frequently draws connections between related disciplines such as Glutamate receptor. His work in the fields of Cell biology, such as RHOA, Signal transduction and Small GTPase, overlaps with other areas such as RhoGAP domain.
His study on Medium spiny neuron also encompasses disciplines like
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CD38 is critical for social behaviour by regulating oxytocin secretion
Duo Jin;Hong Xiang Liu;Hirokazu Hirai;Takashi Torashima.
Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress
Taku Nagai;Kiyofumi Yamada;Kiyofumi Yamada;Hyoung Chun Kim;Yong Sun Kim.
The FASEB Journal (2003)
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction
Kazuhiro Takuma;Fang Fang;Wensheng Zhang;Wensheng Zhang;Shiqiang Yan;Shiqiang Yan.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Social isolation rearing-induced impairment of the hippocampal neurogenesis is associated with deficits in spatial memory and emotion-related behaviors in juvenile mice
Daisuke Ibi;Kazuhiro Takuma;Hiroyuki Koike;Hiroyuki Mizoguchi.
Journal of Neurochemistry (2008)
Silibinin prevents amyloid β peptide-induced memory impairment and oxidative stress in mice
P. Lu;P. Lu;T. Mamiya;L. L. Lu;L. L. Lu;Akihiro Mouri.
British Journal of Pharmacology (2009)
Behavioral abnormality and pharmacologic response in social isolation-reared mice
Hiroyuki Koike;Daisuke Ibi;Hiroyuki Mizoguchi;Taku Nagai.
Behavioural Brain Research (2009)
Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice.
Hiroyuki Kamei;Taku Nagai;Taku Nagai;Hiroko Nakano;Yuriko Togan.
Biological Psychiatry (2006)
Aripiprazole ameliorates phencyclidine-induced impairment of recognition memory through dopamine D1 and serotonin 5-HT1A receptors.
Taku Nagai;Rina Murai;Kanae Matsui;Hiroyuki Kamei.
Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex.
Taku Nagai;Kazuhiro Takuma;Hiroyuki Kamei;Yukio Ito.
Learning & Memory (2007)
Role of Tumor Necrosis Factor-α in Methamphetamine-Induced Drug Dependence and Neurotoxicity
Akira Nakajima;Kiyofumi Yamada;Kiyofumi Yamada;Taku Nagai;Takehisa Uchiyama.
The Journal of Neuroscience (2004)
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