World's Best Scientists 2026 revealed!
Robert L. Medcalf

Robert L. Medcalf

D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
8738
World Ranking
14667
National Ranking
400

Overview

Robert L. Medcalf is affiliated with Monash University in Australia and has made significant contributions in the field of medicine, particularly focusing on hematology and related subfields. Their research spans topics such as blood transfusion and management, trauma and coagulopathy, acute ischemic stroke management, blood coagulation and thrombosis mechanisms, venous thromboembolism diagnosis and management, blood properties and coagulation, as well as protease and inhibitor mechanisms.

Their recent papers highlight active engagement in understanding coagulation and fibrinolysis processes, as well as clinical implications related to trauma and COVID-19. Notable recent publications include:

  • Fibrinolysis and COVID-19: A plasmin paradox, 2020, Journal of Thrombosis and Haemostasis
  • Plasminogen: an enigmatic zymogen, 2021, Blood
  • Prehospital Tranexamic Acid for Severe Trauma, 2023, New England Journal of Medicine
  • Defining trauma-induced coagulopathy with respect to future implications for patient management: Communication from the SSC of the ISTH, 2020, Journal of Thrombosis and Haemostasis
  • Management of the thrombotic risk associated with COVID-19: guidance for the hemostasis laboratory, 2020, Thrombosis Journal

Their collaboration network includes frequent co-authorship with several researchers, revealing a pattern of ongoing teamwork in related studies. Frequent co-authors are:

  • Charithani B. Keragala
  • Dominik F. Draxler
  • Heidi Ho
  • Paul S. Myles
  • Zikou Liu

Robert L. Medcalf's scholarly output is notably published in multiple respected venues. The most recurrent journals where their work appears are:

  • Journal of Thrombosis and Haemostasis
  • Research and Practice in Thrombosis and Haemostasis
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Thrombosis Journal
  • Blood

Their research scope covers a range of specialized subfields including hematology, critical care and intensive care medicine, biochemistry, neurology, and epidemiology. These areas collectively inform their scientific investigations and clinical research directions.

Best Publications

  • Tissue-type plasminogen activator: a multifaceted modulator of neurotransmission and synaptic plasticity.

    Andre Laval Samson;Robert Lindsay Medcalf

  • Vampire bat salivary plasminogen activator (desmoteplase): a unique fibrinolytic enzyme that does not promote neurodegeneration.

    Gabriel T Liberatore;Andre L Samson;Christopher Bladin;Wolf-Dieter Schleuning

  • Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter.

    Michael Zimmer;Robert L. Medcalf;Thomas M. Fink;Chantal Mattmann

  • Glucocorticoid-modulated gene expression of tissue- and urinary-type plasminogen activator and plasminogen activator inhibitor 1 and 2.

    R L Medcalf;E Van den Berg;W D Schleuning

  • A DNA motif related to the cAMP-responsive element and an exon-located activator protein-2 binding site in the human tissue-type plasminogen activator gene promoter cooperate in basal expression and convey activation by phorbol ester and cAMP.

    R L Medcalf;M Rüegg;W D Schleuning

  • Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation

    Lynette Pretorius;Lynette Pretorius;Xiao-Jun Du;Elizabeth A Woodcock;Helen Kiriazis

  • Sodium selenate reduces hyperphosphorylated tau and improves outcomes after traumatic brain injury

    Sandy R Shultz;David K Wright;Ping Zheng;Ryan Stuchbery

  • Fibrinolysis, inflammation, and regulation of the plasminogen activating system

    Robert Lindsay Medcalf

  • The undecided serpin. The ins and outs of plasminogen activator inhibitor type 2.

    Robert Lindsay Medcalf;Stan J Stasinopoulos

  • Plasminogen activator inhibitor 1 and 2 are tumor necrosis factor/cachectin-responsive genes.

    Robert L. Medcalf;Egbert K.O. Kruithof;Wolf Dieter Schleuning

  • Plasminogen-activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma cells

    J. F. Cajot;J. Bamat;G. E. Bergonzelli;E. K. O. Kruithof

  • Haemostasis and innate immunity - a complementary relationship: A review of the intricate relationship between coagulation and complement pathways.

    Charithani B. Keragala;Dominik F. Draxler;Zoe K. McQuilten;Robert L. Medcalf

  • Inhibition of interleukin 1β-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP

    Christine J. Hawkins;Anthony G. Uren;Georg Häcker;Robert L. Medcalf

  • What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies.

    Roberto Picetti;Haleema Shakur-Still;Robert L. Medcalf;Joseph F. Standing

  • Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells.

    W.-D. Schleuning;R. L. Medcalf;C. Hession;R. Rothenbühler

  • Mouse L cells expressing human prourokinase-type plasminogen activator: effects on extracellular matrix degradation and invasion.

    J F Cajot;W D Schleuning;R L Medcalf;J Bamat

  • Tissue-type plasminogen activator requires a co-receptor to enhance NMDA receptor function

    Andre Laval Samson;Simon T Nevin;David Croucher;Be'eri Niego

  • Issue Editorial Focus : Issue Editorial Focus

    Yoshikuni Nagamine;Robert L. Medcalf;Pura Munoz-Canoves

  • Novel Role of Platelets in Mediating Inflammatory Responses and Ventricular Rupture or Remodeling Following Myocardial Infarction

    Yang Liu;Xiao-Ming Gao;Lu Fang;Nicole L. Jennings

  • Vampire Bat Salivary Plasminogen Activator (Desmoteplase) Inhibits Tissue-Type Plasminogen Activator-Induced Potentiation of Excitotoxic Injury

    Courtney Reddrop;Randal Xavier Moldrich;Philip M Beart;Mark Farso

Frequent Co-Authors

Paul S. Myles
Paul S. Myles Monash University
Daniel A. Lawrence
Daniel A. Lawrence University of Michigan–Ann Arbor
Magdalena Plebanski
Magdalena Plebanski RMIT University
Yoshikuni Nagamine
Yoshikuni Nagamine Friedrich Miescher Institute
Stephen P. Bottomley
Stephen P. Bottomley Monash University
Leigh A. Johnston
Leigh A. Johnston University of Melbourne
Ann M. Turnley
Ann M. Turnley University of Melbourne
Elizabeth G. Holliday
Elizabeth G. Holliday University of Newcastle Australia
Nigel C. Jones
Nigel C. Jones Monash University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring online degrees related to Biology and Biochemistry can open doors to diverse career pathways in healthcare, research, and laboratory settings. As the demand for qualified professionals continues to grow, flexible online options make these fields more accessible than ever.

For those interested in nutrition, dietitian masters programs offer advanced study and prepare graduates for roles as registered dietitians. If you’d like to work directly with patients, consider pursuing online medical assistant programs fafsa approved to get started in the medical field with financial support options.

Professionals looking to advance can also explore the medical assistant to lpn bridge program online, which enables medical assistants to become Licensed Practical Nurses without leaving their current jobs. Meanwhile, those seeking a quicker path to a biology degree should investigate accelerated biology degree programs that reduce the time needed to graduate.

Each pathway offers unique advantages, whether you’re beginning your education or upskilling for career advancement in the biosciences.

Best Scientists Citing Robert L. Medcalf

Trending Scientists