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Immunology

D-Index
129
Citations
80038
World Ranking
239
National Ranking
157

Medicine

D-Index
129
Citations
80039
World Ranking
2545
National Ranking
1432

Research.com Recognitions

  • 2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
  • 2017 - Member of the National Academy of Sciences
  • 2005 - Fellow of the American Academy of Arts and Sciences
  • 2003 - AAI Distinguished Service Award, American Association of Immunologists For distinguished service as AAI Annual Meeting and Program Committee Chairman, 2000-2003
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Richard M. Locksley is affiliated with the University of California, San Francisco in the United States. Their work primarily spans the fields of Immunology and Microbiology, with significant contributions also intersecting Medicine. Areas of focused subfields include Immunology, Surgery, Molecular Biology, Dermatology, and Insect Science.

Locksley has contributed extensively to research on immune pathways and cell interactions. Key topics in their work cover:

  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Eosinophilic Esophagitis
  • Dermatology and Skin Diseases
  • Studies on Chitinases and Chitosanases
  • Insect symbiosis and bacterial influences
  • Asthma and respiratory diseases

Their frequent coauthors include Hong-Erh Liang, Roberto R. Ricardo-González, Maya E. Kotas, Claire E. O'Leary, and Roberto Efraín Díaz.

Frequent publication venues for Locksley's work are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Experimental Medicine
  • The Journal of Immunology
  • Immunity
  • Science Immunology

Recent notable papers include:

  • Skin-resident innate lymphoid cells converge on a pathogenic effector state (2021, Nature)
  • Alveolar macrophages rely on GM-CSF from alveolar epithelial type 2 cells before and after birth (2021, The Journal of Experimental Medicine)
  • In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors (2020, Immunity)
  • Tissue-specific pathways extrude activated ILC2s to disseminate type 2 immunity (2020, The Journal of Experimental Medicine)
  • Interferon gamma constrains type 2 lymphocyte niche boundaries during mixed inflammation (2022, Immunity)

Throughout their career, Locksley has been recognized with several awards and honors, including:

  • Distinguished Fellows of the American Association of Immunologists (AAI) in 2019
  • Member of the National Academy of Sciences since 2017
  • Fellow of the American Academy of Arts and Sciences since 2005
  • AAI Distinguished Service Award in 2003 for service as AAI Annual Meeting and Program Committee Chairman (2000-2003)
  • Member of the Association of American Physicians

Best Publications

  • The TNF and TNF receptor superfamilies: integrating mammalian biology.

    Richard M. Locksley;Nigel Killeen;Michael J. Lenardo

  • TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-Producing T cells

    Marc Veldhoen;Richard J. Hocking;Christopher J. Atkins;Richard M. Locksley

  • Requirement for IL-13 independently of IL-4 in experimental asthma

    G. Grünig;M. Warnock;A. E. Wakil;R. Venkayya

  • Innate lymphoid cells--a proposal for uniform nomenclature.

    Hergen Spits;David Artis;Marco Colonna;Andreas Diefenbach

  • The instructive role of innate immunity in the acquired immune response.

    Douglas T. Fearon;Richard M. Locksley

  • Innate Lymphoid Cells: 10 Years On.

    Eric Vivier;David Artis;Marco Colonna;Andreas Diefenbach

  • Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis. Evidence for expansion of distinct helper T cell subsets.

    F P Heinzel;M D Sadick;B J Holaday;R L Coffman

  • IL-23 and IL-17 in the establishment of protective pulmonary CD4 + T cell responses after vaccination and during Mycobacterium tuberculosis challenge

    Shabaana A Khader;Guy K Bell;John E Pearl;Jeffrey J Fountain

  • The regulation of immunity to Leishmania major.

    Steven L Reiner;Richard M Locksley

  • Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

    Davina Wu;Ari B. Molofsky;Hong Erh Liang;Roberto R. Ricardo-Gonzalez

  • Systemically dispersed innate IL-13-expressing cells in type 2 immunity.

    April E. Price;Hong-Erh Liang;Brandon M. Sullivan;R. Lee Reinhardt

  • Tuft-cell-derived IL-25 regulates an intestinal ILC2–epithelial response circuit

    Jakob von Moltke;Ming Ji;Hong-Erh Liang;Richard M. Locksley

  • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

    Khoa D. Nguyen;Yifu Qiu;Xiaojin Cui;Y. P. Sharon Goh;Y. P. Sharon Goh

  • Type 2 innate lymphoid cells control eosinophil homeostasis

    Jesse C. Nussbaum;Steven J. Van Dyken;Jakob Von Moltke;Laurence E. Cheng

  • Identification of a Coordinate Regulator of Interleukins 4, 13, and 5 by Cross-Species Sequence Comparisons

    Gabriela G. Loots;Gabriela G. Loots;Richard M. Locksley;Catherine M. Blankespoor;Zhi-En Wang

  • Cytokine-secreting follicular T cells shape the antibody repertoire

    R Lee Reinhardt;Hong-Erh Liang;Richard M Locksley

  • Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

    Qizhi Tang;Jason Yeates Adams;Aaron J. Tooley;Mingying Bi

  • Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

    Ari B. Molofsky;Jesse C. Nussbaum;Hong-Erh Liang;Steven J. Van Dyken

  • Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat

    Yifu Qiu;Khoa D. Nguyen;Justin I. Odegaard;Xiaojin Cui

  • Chitin induces accumulation in tissue of innate immune cells associated with allergy

    Tiffany A. Reese;Hong-Erh Liang;AndrewN M. Tager;Andrew D. Luster

  • Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.

    David B. Corry;Hans G. Folkesson;Martha L. Warnock;David J. Erle

Frequent Co-Authors

David B. Corry
David B. Corry Baylor College of Medicine
David Voehringer
David Voehringer University of Erlangen-Nuremberg
Markus Mohrs
Markus Mohrs Trudeau Institute
Ajay Chawla
Ajay Chawla University of California, San Francisco
Jacques A. Louis
Jacques A. Louis Institut Pasteur
David J. Erle
David J. Erle University of California, San Francisco
Seymour J. Klebanoff
Seymour J. Klebanoff University of Washington
Matthew F. Krummel
Matthew F. Krummel University of California, San Francisco
Nigel Killeen
Nigel Killeen University of California, San Francisco
John V. Fahy
John V. Fahy University of California, San Francisco

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