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Roger J. W. Truscott

Roger J. W. Truscott

D-Index & Metrics

Chemistry

D-Index
63
Citations
12374
World Ranking
8551
National Ranking
199

Biology and Biochemistry

D-Index
65
Citations
12971
World Ranking
9299
National Ranking
242

Overview

Roger J. W. Truscott is affiliated with the University of Wollongong in Australia. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with additional work in Medicine. The subfields of study associated with their work include Molecular Biology, Clinical Biochemistry, Physiology, Cellular and Molecular Neuroscience, and Materials Chemistry.

The scientist's work covers specific topics such as:

  • Connexins and lens biology
  • Neuroscience and Neuropharmacology Research
  • Biochemical effects in animals
  • Enzyme Structure and Function
  • Advanced Glycation End Products research
  • Mitochondrial Function and Pathology
  • Metabolism and Genetic Disorders

Roger J. W. Truscott has published research in several scientific journals, including:

  • Nutrients
  • ACS Chemical Biology
  • International Journal of Molecular Sciences
  • Biochemical Journal
  • Experimental Eye Research

Some of their recent papers are:

  • "Changes in Phospholipid Composition of the Human Cerebellum and Motor Cortex during Normal Ageing" (2022), published in Nutrients
  • "Tau Is Truncated in Five Regions of the Normal Adult Human Brain" (2021), published in International Journal of Molecular Sciences
  • "Spontaneous Cleavage at Glu and Gln Residues in Long-Lived Proteins" (2021), published in ACS Chemical Biology
  • "New insights into the mechanisms of age-related protein-protein crosslinking in the human lens" (2021), published in Experimental Eye Research
  • "Spontaneous protein-protein crosslinking at glutamine and glutamic acid residues in long-lived proteins" (2020), published in Biochemical Journal

Their frequent co-authors include:

  • Michael G. Friedrich
  • Kevin L. Schey
  • Sarah E. Hancock
  • Todd W. Mitchell
  • Paul L. Else

Best Publications

  • Age-related nuclear cataract-oxidation is the key.

    Roger J.W. Truscott

  • Photo-oxidation of proteins and its role in cataractogenesis.

    Michael J. Davies;Roger J.W. Truscott

  • Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia?

    Karl Robert Heys;Sandra Leigh Cram;Roger John Willis Truscott

  • An impediment to glutathione diffusion in older normal human lenses: a possible precondition for nuclear cataract.

    Matthew H.J. Sweeney;Roger J.W. Truscott

  • Age-related nuclear cataract: a lens transport problem

    Roger J.W. Truscott

  • The Hydroxyl Radical in Lens Nuclear Cataractogenesis

    Shanlin Fu;Roger Dean;Michael Southan;Roger Truscott

  • Major changes in human ocular UV protection with age

    Lisa M. Bova;Matthew H. J. Sweeney;Joanne F. Jamie;Roger J. W. Truscott

  • Regulation of tissue oxygen levels in the mammalian lens

    Richard McNulty;Huan Wang;Richard T. Mathias;Beryl J. Ortwerth

  • Post-translational modifications in the nuclear region of young, aged, and cataract human lenses.

    Peter G Hains;Roger J W Truscott

  • Novel protein modification by kynurenine in human lenses.

    Santiago Vazquez;J. Andrew Aquilina;Joanne F Jamie;Margaret M Sheil

  • Identification by 1H NMR spectroscopy of flexible C‐terminal extensions in bovine lens α‐crystallin

    John A. Carver;J.Andrew Aquilina;Roger J.W. Truscott;Gregory B. Ralston

  • Human lens coloration and aging. Evidence for crystallin modification by the major ultraviolet filter, 3-hydroxy-kynurenine O-beta-D-glucoside.

    Brian D. Hood;Brett Garner;Roger J.W. Truscott

  • UV filters in human lenses : tryptophan catabolism

    Andrew M. Wood;Roger J.W. Truscott

  • Human lens lipids differ markedly from those of commonly used experimental animals

    Jane M. Deeley;Todd W. Mitchell;Xiaojia Wei;John Korth

  • Age-related Changes in the Kinetics of Water Transport in Normal Human Lenses

    B.A Moffat;K.A Landman;R.J.W Truscott;M.H.J Sweeney

  • Racemisation and human cataract. d -Ser, d -Asp/Asn and d -Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lenses

    Michelle Yu Sung Hooi;Roger J. W. Truscott

  • Age-dependent deamidation of lifelong proteins in the human lens.

    Peter G. Hains;Roger J. W. Truscott

  • On the interaction of α-crystallin with unfolded proteins

    John A. Carver;Nelson Guerreiro;Kerrie A. Nicholls;Roger J.W. Truscott

  • Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility.

    Karl R. Heys;Michael G. Friedrich;Michael G. Friedrich;Roger J. W. Truscott

  • A possible chaperone-like quaternary structure for alpha-crystallin.

    J.A. Carver;J.A. Aquilina;R.J.W. Truscott

  • Protein-bound kynurenine is a photosensitizer of oxidative damage.

    Nicole R. Parker;Joanne F. Jamie;Michael J. Davies;Roger J.W. Truscott

Frequent Co-Authors

Michael J. Davies
Michael J. Davies University of Copenhagen
John A. Carver
John A. Carver Australian National University
Stephen J. Blanksby
Stephen J. Blanksby Queensland University of Technology
Stephen G. Pyne
Stephen G. Pyne University of Wollongong
Kevin L. Schey
Kevin L. Schey Vanderbilt University
Brett Garner
Brett Garner University of Wollongong
Mark J. Raftery
Mark J. Raftery University of New South Wales
Mark J. Walker
Mark J. Walker University of Queensland
Danuta S. Kalinowski
Danuta S. Kalinowski University of Sydney
Friedrich Leisch
Friedrich Leisch BOKU University

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