Charles Heidelberger

Research.com Recognitions

• 1978 - Member of the National Academy of Sciences
• 1963 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Best Publications

• Fluorinated Pyrimidines, A New Class of Tumour-Inhibitory Compounds

  Charles Heidelberger;N. K. Chaudhuri;Peter Danneberg;Dorothy Mooren

  2159
  Citations

• Establishment and characterization of a cloned line of C3H mouse embryo cells sensitive to postconfluence inhibition of division.

  Catherine A. Reznikoff;David W. Brankow;Charles Heidelberger

  1611
  Citations

• Quantitative and qualitative studies of chemical transformation of cloned C3H mouse embryo cells sensitive to postconfluence inhibition of cell division.

  Catherine A. Reznikoff;John S. Bertram;David W. Brankow;Charles Heidelberger

  1226
  Citations

• Selective heat sensitivity of cancer cells. Biochemical and clinical studies.

  Renato Cavaliere;Enrico C. Ciocatto;Beppino C. Giovanella;Charles Heidelberger

  1140
  Citations

• THE SYNTHESIS OF 5-FLUOROPYRIMIDINES

  Robert Duschinsky;Edward Pleven;Charles Heidelberger

  659
  Citations

• Studies on Fluorinated Pyrimidines II. Effects on Transplanted Tumors

  Charles Heidelberger;Lois Griesbach;Betty Jo Montag;Dorothy Mooren

  642
  Citations

• Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase.

  K-U. Hartmann;Charles Heidelberger

  589
  Citations

• Fluorinated Pyrimidines and Their Nucleosides

  Charles Heidelberger;Peter V. Danenberg;Richard G. Moran

  468
  Citations

• Two-stage chemical oncogenesis in cultures of c3h/10t1/2 cells.

  Sukdeb Mondal;David W. Brankow;Charles Heidelberger

  439
  Citations

• In Vivo Kinetics of Thymidylate Synthetase Inhibition in 5-Fluorouracil-sensitive and -resistant Murine Colon Adenocarcinomas

  C. Paul Spears;Antranik H. Shahinian;Richard G. Moran;Charles Heidelberger

  385
  Citations

• Studies on fluorinated pyrimidines. III. The metabolism of 5-fluorouracil-2-C14 and 5-fluoroorotic-2-C14 acid in vivo.

  N. K. Chaudhuri;Betty Jo Montag;Charles Heidelberger

  350
  Citations

• Studies on fluorinated pyrimidines. IV. Effects on nucleic acid metabolism in vivo.

  Peter B. Danneberg;Betty Jo Montag;Charles Heidelberger

  347
  Citations

• Quantitative studies on the malignant transformation of mouse prostate cells by carcinogenic hydrocarbons in vitro.

  T. T. Chen;Charles Heidelberger

  322
  Citations

• EXPERIMENTAL AND CLINICAL USE OF FLUORINATED PYRIMIDINES IN CANCER CHEMOTHERAPY

  Charles Heidelberger;Fred J. Ansfield

  306
  Citations

• Cell transformation by chemical agents--a review and analysis of the literature. A report of the U.S. Environmental Protection Agency Gene-Tox Program.

  Charles Heidelberger;Aaron E Freeman;Roman J Pienta;Andrew Sivak

  305
  Citations

• Studies on the quantitative biology of hyperthermic killing of HeLa cells.

  Robert J. Palzer;Charles Heidelberger

  286
  Citations

• SYNTHESES OF 5-TRIFLUOROMETHYLURACIL AND 5-TRIFLUOROMETHYL-2'-DEOXYURIDINE.

  Charles Heidelberger;David G. Parsons;David C. Remy

  283
  Citations

• Thymidylate synthetase: mechanism of inhibition by 5-fluoro-2'-deoxyuridylate.

  R.J. Langenbach;P.V. Danenberg;Charles Heidelberger

  274
  Citations

• Clinical Studies with 5-Fluorouracil

  A. R. Curreri;Fred J. Ansfield;Forde A. McIver;Harry A. Waisman

  270
  Citations

• Fluorinated pyrimidines. XXVI. Mammalian thymidylate synthetase: its mechanism of action and inhibition by fluorinated nucleotides.

  Philip Reyes;Charles Heidelberger

  270
  Citations