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Medicine

D-Index
86
Citations
31007
World Ranking
14002
National Ranking
7106

Overview

Carmen J. Allegra is affiliated with the University of Florida in the United States and has contributed extensively to the field of medicine, with a focus on oncology. Their research encompasses a range of subfields, including oncology, cancer research, pulmonary and respiratory medicine, pathology and forensic medicine, and surgery.

The scientist's work covers several main topics within cancer studies, particularly concentrating on colorectal cancer. These topics include colorectal cancer treatments and studies, cancer genomics and diagnostics, genetic factors in colorectal cancer, pancreatic and hepatic oncology research, cancer immunotherapy and biomarkers, colorectal cancer surgical treatments, and PARP inhibition in cancer therapy.

Among their recent published papers are:

  • Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406), 2020, Journal of Clinical Oncology
  • ctDNA applications and integration in colorectal cancer: an NCI Colon and Rectal-Anal Task Forces whitepaper, 2020, Nature Reviews Clinical Oncology
  • Microsatellite Instability in Patients With Stage III Colon Cancer Receiving Fluoropyrimidine With or Without Oxaliplatin: An ACCENT Pooled Analysis of 12 Adjuvant Trials, 2020, Journal of Clinical Oncology
  • Sex and Adverse Events of Adjuvant Chemotherapy in Colon Cancer: An Analysis of 34,640 Patients in the ACCENT Database, 2020, JNCI Journal of the National Cancer Institute
  • BCL-XL PROTAC degrader DT2216 synergizes with sotorasib in preclinical models of KRASG12C-mutated cancers, 2022, Journal of Hematology & Oncology

The scientist has collaborated frequently with several coauthors, including Thomas J. George, Norman Wolmark, Ji-Hyun Lee, Greg Yothers, and David L. DeRemer. Their publication record shows considerable involvement with leading venues in the field such as the Journal of Clinical Oncology, UNC Libraries, Cancer Research, JNCI Journal of the National Cancer Institute, and Breast Cancer Research.

The largest number of publications are in the Journal of Clinical Oncology, indicating a strong emphasis on clinical cancer research related to oncology. This aligns with their primary research areas and their contributions to both clinical trials and cancer genomics.

Best Publications

  • American Society of Clinical Oncology Provisional Clinical Opinion: Testing for KRAS Gene Mutations in Patients With Metastatic Colorectal Carcinoma to Predict Response to Anti-Epidermal Growth Factor Receptor Monoclonal Antibody Therapy

    Carmen J. Allegra;Carmen J. Allegra;J. Milburn Jessup;Mark R. Somerfield;Stanley R. Hamilton

  • Addition of Aflibercept to Fluorouracil, Leucovorin, and Irinotecan Improves Survival in a Phase III Randomized Trial in Patients With Metastatic Colorectal Cancer Previously Treated With an Oxaliplatin-Based Regimen

    Eric Van Cutsem;Josep Tabernero;Radek Lakomy;Hans Prenen

  • Preoperative Multimodality Therapy Improves Disease-Free Survival in Patients With Carcinoma of the Rectum: NSABP R-03

    Mark S. Roh;Linda H. Colangelo;Michael J. O'Connell;Greg Yothers

  • Thymidylate Synthase Gene and Protein Expression Correlate and Are Associated with Response to 5-Fluorouracil in Human Colorectal and Gastric Tumors

    Patrick G. Johnston;Heinz-Josef Lenz;Cynthia G. Leichman;Kathleen D. Danenberg

  • Oxaliplatin As Adjuvant Therapy for Colon Cancer: Updated Results of NSABP C-07 Trial, Including Survival and Subset Analyses

    Greg Yothers;Michael J. O'Connell;Carmen J. Allegra;J. Philip Kuebler

  • Phase III Trial Assessing Bevacizumab in Stages II and III Carcinoma of the Colon: Results of NSABP Protocol C-08

    Carmen J. Allegra;Greg Yothers;Michael J. O'Connell;Saima Sharif

  • Clinical Trial Designs for Predictive Marker Validation in Cancer Treatment Trials

    Daniel J. Sargent;Barbara A. Conley;Carmen Allegra;Laurence Collette

  • Polyglutamation of methotrexate. Is methotrexate a prodrug

    B A Chabner;C J Allegra;G A Curt;N J Clendeninn

  • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer.

    P G Johnston;E R Fisher;H E Rockette;B Fisher

  • DNA Mismatch Repair Status and Colon Cancer Recurrence and Survival in Clinical Trials of 5-Fluorouracil-Based Adjuvant Therapy

    Frank A. Sinicrope;Nathan R. Foster;Stephen N. Thibodeau;Silvia Marsoni

  • Capecitabine and Oxaliplatin in the Preoperative Multimodality Treatment of Rectal Cancer: Surgical End Points From National Surgical Adjuvant Breast and Bowel Project Trial R-04

    Michael J. O'Connell;Linda H. Colangelo;Robert W. Beart;Nicholas J. Petrelli

  • Prognostic and Predictive Roles of High-Degree Microsatellite Instability in Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

    George P. Kim;Linda H. Colangelo;H. Samuel Wieand;Soonmyung Paik

  • Inhibition of phosphoribosylaminoimidazolecarboxamide transformylase by methotrexate and dihydrofolic acid polyglutamates.

    Carmen J. Allegra;James C. Drake;Jacques Jolivet;Bruce A. Chabner

  • Randomized Trial of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF-Mutant Metastatic Colorectal Cancer (SWOG S1406)

    Scott Kopetz;Katherine A. Guthrie;Van K. Morris;Heinz Josef Lenz

  • Prognostic Value of Thymidylate Synthase, Ki-67, and p53 in Patients With Dukes’ B and C Colon Cancer: A National Cancer Institute–National Surgical Adjuvant Breast and Bowel Project Collaborative Study

    Carmen J. Allegra;Soon Paik;Linda H. Colangelo;Allyson L. Parr

  • Molecular biomarkers for the evaluation of colorectal cancer: Guideline from The American Society for Clinical Pathology, College of American Pathologists, Association for Molecular Pathology, and the American Society of Clinical Oncology

    Antonia R. Sepulveda;Antonia R. Sepulveda;Stanley R. Hamilton;Carmen J. Allegra;Wayne Grody

  • Fluorouracil and high-dose leucovorin in previously treated patients with metastatic breast cancer.

    S M Swain;M E Lippman;E F Egan;J C Drake

  • National Institutes of Health State-of-the-Science Conference Statement: Diagnosis and Management of Ductal Carcinoma In Situ September 22–24, 2009

    Carmen J. Allegra;Denise R. Aberle;Pamela Ganschow;Stephen M. Hahn

  • Initial Safety Report of NSABP C-08: A Randomized Phase III Study of Modified FOLFOX6 With or Without Bevacizumab for the Adjuvant Treatment of Patients With Stage II or III Colon Cancer

    Carmen J. Allegra;Greg Yothers;Michael J. O'Connell;Saima Sharif

  • Immunological quantitation of thymidylate synthase using the monoclonal antibody TS 106 in 5-fluorouracil-sensitive and -resistant human cancer cell lines.

    Patrick G. Johnston;James C. Drake;Jane Trepel;Carmen J. Allegra

Frequent Co-Authors

Bruce A. Chabner
Bruce A. Chabner Harvard University
Norman Wolmark
Norman Wolmark University of Pittsburgh
Patrick G. Johnston
Patrick G. Johnston Queen's University Belfast
Richard M. Goldberg
Richard M. Goldberg West Virginia University
Seth M. Steinberg
Seth M. Steinberg National Institutes of Health
Soonmyung Paik
Soonmyung Paik Yonsei University
Henry Masur
Henry Masur National Institutes of Health

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